Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations

El Bissati, K, Redel, H, Ting, L-M et al. (7 more authors) (2019) Novel Synthetic Polyamines Have Potent Antimalarial Activities in vitro and in vivo by Decreasing Intracellular Spermidine and Spermine Concentrations. Frontiers in Cellular and Infection Microbiology, 9. 9. ISSN 2235-2988

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2019 El Bissati, Redel, Ting, Lykins, McPhillie, Upadhya, Woster, Yarlett, Kim and Weiss. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: polyamine; Plasmodium; malaria; spermidine; spermine; spermidine synthase; thiourea
Dates:
  • Published: 14 February 2019
  • Accepted: 14 January 2019
  • Published (online): 14 February 2019
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 01 Mar 2019 15:20
Last Modified: 01 Mar 2019 15:20
Status: Published
Publisher: Frontiers Media
Identification Number: https://doi.org/10.3389/fcimb.2019.00009

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