Dale, K.D., Trauer, J.M., Dodd, P.J. orcid.org/0000-0001-5825-9347 et al. (2 more authors) (2018) Estimating the prevalence of latent tuberculosis in a low incidence setting: Australia. European Respiratory Journal, 52 (6). 1801218. ISSN 0903-1936
Abstract
Migration is a key driver of tuberculosis (TB) in many low incidence settings, with the majority of TB cases attributed to reactivation of latent TB (LTBI) acquired overseas. A greater understanding of LTBI risk in heterogeneous migrant populations would aid health planning. We aimed to estimate the LTBI prevalence and distribution among local and overseas-born Australians.Annual risks of tuberculosis infection estimates were applied to population cohorts (by country of birth, year of arrival and age) in Australian census data in 2006, 2011 and 2016.Both the absolute number and proportion of Australian residents with LTBI increased - from 4.6% (IQR [interquartile range] 4.2-5.2%) in 2006 to 5.1% (IQR 4.7%-5.5%) in 2016 - due to the increasing proportion of the population born overseas (23.8% in 2006 to 28.3% in 2016). Of all residents estimated to have LTBI in 2016; 93.2% were overseas born, 21.6% were <35 years of age and 34.4% had migrated to Australia since 2007.The overall prevalence of LTBI in Australia is low. Some residents, particularly migrants from high incidence settings, may have considerably higher risk of LTBI, and these findings allow for tailored public health interventions to reduce the risk and impact of future TB disease.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2018 ERS. This is an author produced version of a paper subsequently published in European Respiratory Journal. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | Migration; epidemiologic methods; mathematical modelling |
Dates: |
|
Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Funding Information: | Funder Grant number MEDICAL RESEARCH COUNCIL MR/P022081/1 |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 23 Nov 2018 12:32 |
Last Modified: | 17 May 2024 11:15 |
Status: | Published |
Publisher: | European Respiratory Society |
Refereed: | Yes |
Identification Number: | 10.1183/13993003.01218-2018 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:138988 |