Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia

Walker, C. and El-Khamisy, S.F. orcid.org/0000-0003-2721-7763 (2018) Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia. Brain, 141 (5). pp. 1247-1262. ISSN 0006-8950

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © The Author(s) (2018). Published by Oxford University Press on behalf of the Guarantors of Brain. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
Keywords: R-loops; autophagy; DNA repair; genomic instability; neurodegeneration
Dates:
  • Accepted: 9 February 2018
  • Published (online): 23 March 2018
  • Published: 1 May 2018
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Molecular Biology and Biotechnology (Sheffield)
Funding Information:
FunderGrant number
LISTER INSTITUTE OF PREVENTATIVE MEDICINENONE
WELLCOME TRUST (THE)103844/Z/14/Z
Depositing User: Symplectic Sheffield
Date Deposited: 19 Sep 2018 14:50
Last Modified: 19 Sep 2018 14:50
Published Version: https://doi.org/10.1093/brain/awy076
Status: Published
Publisher: Oxford University Press
Refereed: Yes
Identification Number: https://doi.org/10.1093/brain/awy076
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