Maiden, T.M.M., Mbelesi, N., Procopiou, P.A. orcid.org/0000-0001-5907-116X et al. (2 more authors) (2018) A convergent strategy towards febrifugine and related compounds. Organic and Biomolecular Chemistry, 16 (22). pp. 4159-4169. ISSN 1477-0520
Abstract
We report a modular five step synthetic route to the febrifugines that employs 2-(chloromethyl)allyl-trimethylsilane as a conjunctive reagent for the coupling of the piperidine and quinazolinone groups. We also demonstrate the application of a recent Rh-catalyzed quinazolinone synthesis for the facile generation of febrifugine analogs.
Metadata
| Item Type: | Article |
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| Authors/Creators: |
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| Copyright, Publisher and Additional Information: | © 2018 The Royal Society of Chemistry. This is an author produced version of a paper subsequently published in Organic and Biomolecular Chemistry. Uploaded in accordance with the publisher's self-archiving policy. |
| Dates: |
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| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
| Depositing User: | Symplectic Sheffield |
| Date Deposited: | 30 May 2018 13:04 |
| Last Modified: | 19 Apr 2021 09:48 |
| Status: | Published |
| Publisher: | Royal Society of Chemistry |
| Refereed: | Yes |
| Identification Number: | 10.1039/c8ob00935j |
| Related URLs: | |
| Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:131397 |

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