SPIRE - combining SGI-110 with cisplatin and gemcitabine chemotherapy for solid malignancies including bladder cancer: study protocol for a phase Ib/randomised IIa open label clinical trial

Crabb, S., Danson, S.J., Catto, J.W.F. orcid.org/0000-0003-2787-8828 et al. (12 more authors) (2018) SPIRE - combining SGI-110 with cisplatin and gemcitabine chemotherapy for solid malignancies including bladder cancer: study protocol for a phase Ib/randomised IIa open label clinical trial. Trials, 19. 216. ISSN 1745-6215

Abstract

Metadata

Authors/Creators:
  • Crabb, S.
  • Danson, S.J.
  • Catto, J.W.F. https://orcid.org/0000-0003-2787-8828
  • McDowell, C.
  • Lowder, J.N.
  • Caddy, J.
  • Dunkley, D.
  • Rajaram, J.
  • Ellis, D.
  • Hill, S.
  • Hathorn, D.
  • Whitehead, A.
  • Kalevras, M.
  • Huddart, R.
  • Griffiths, G.
Copyright, Publisher and Additional Information: © The Author(s). 2018. This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
Keywords: Urothelial bladder cancer; Guadecitabine; DNA methyltransferase inhibitor; Phase I/II; Randomised controlled trial; Cisplatin resistance
Dates:
  • Published: 3 April 2018
  • Published (online): 3 April 2018
  • Accepted: 8 March 2018
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 10 May 2018 11:43
Last Modified: 10 May 2018 17:47
Published Version: https://doi.org/10.1186/s13063-018-2586-7
Status: Published
Publisher: BioMed Central
Refereed: Yes
Identification Number: https://doi.org/10.1186/s13063-018-2586-7
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