Hawkins, R.J. (2018) Do migrating cells need a nucleus? Journal of Cell Biology, 217 (3). pp. 799-801. ISSN 0021-9525
Abstract
How the nucleus affects cell polarity and migration is unclear. In this issue, Graham et al. (2018. J. Cell Biol. https://doi.org /10.1083/jcb.201706097) show that enucleated cells polarize and migrate in two but not three dimensions and propose that the nucleus is a necessary component of the molecular clutch regulating normal mechanical responses.
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Copyright, Publisher and Additional Information: | © 2018 Hawkins http://www.rupress.org/terms/ https://creativecommons.org/licenses/by-nc-sa/4.0/ This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/). | ||||
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Institution: | The University of Sheffield | ||||
Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Physics and Astronomy (Sheffield) | ||||
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Depositing User: | Symplectic Sheffield | ||||
Date Deposited: | 05 Apr 2018 12:06 | ||||
Last Modified: | 05 Apr 2018 12:06 | ||||
Published Version: | https://doi.org/10.1083/jcb.201802054 | ||||
Status: | Published | ||||
Publisher: | Rockefeller University Press | ||||
Refereed: | Yes | ||||
Identification Number: | https://doi.org/10.1083/jcb.201802054 | ||||
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