A Type III Complement Factor D Deficiency: Structural insights for inhibition of the alternative pathway

Sng, CCT, O’Byrne, S, Prigozhin, DM et al. (16 more authors) (2018) A Type III Complement Factor D Deficiency: Structural insights for inhibition of the alternative pathway. Journal of Allergy and Clinical Immunology, 142 (1). 311-314.e6. ISSN 0091-6749

Metadata

Authors/Creators:
  • Sng, CCT
  • O’Byrne, S
  • Prigozhin, DM
  • Bauer, MR
  • Harvey, JC
  • Ruhle, M
  • Challis, BG
  • Lear, S
  • Roberts, LD https://orcid.org/0000-0002-1455-5248
  • Workman, S
  • Janowitz, T
  • Magiera, L
  • Doffinger, R
  • Buckland, MS
  • Jodrell, DJ
  • Semple, RK
  • Wilson, TJ
  • Modis, Y
  • Thaventhiran, JED
Copyright, Publisher and Additional Information: (c) 2018 American Academy of Allergy, Asthma & Immunology. This is an open access article under the terms of the Creative Commons Attribution 4.0 International licence (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/
Keywords: Adipsin; age-related macular degeneration; alternative pathway; complement deficiency; complement serine protease; drug development; factor D; glucose homeostasis; single-nucleotide variant; type III deficiency
Dates:
  • Published: July 2018
  • Accepted: 16 January 2018
  • Published (online): 6 March 2018
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds)
Funding Information:
FunderGrant number
Diabetes UK16/0005382
Depositing User: Symplectic Publications
Date Deposited: 13 Mar 2018 14:45
Last Modified: 06 Mar 2019 01:38
Status: Published
Publisher: Elsevier
Identification Number: https://doi.org/10.1016/j.jaci.2018.01.048

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