Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM

Rawson, S., Bisson, C. orcid.org/0000-0002-9430-6822, Hurdiss, D.L. orcid.org/0000-0003-3834-5808 et al. (6 more authors) (2018) Elucidating the structural basis for differing enzyme inhibitor potency by cryo-EM. Proceedings of the National Academy of Sciences, 115 (8). pp. 1795-1800. ISSN 0027-8424

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2018 the Author(s). Published by PNAS. This open access article is distributed under Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (CC BY-NC-ND).
Keywords: IGPD; electron microscopy; enzyme inhibition; histidine biosynthesis; structure-based drug design
Dates:
  • Published: 6 February 2018
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Molecular Biology and Biotechnology (Sheffield)
Funding Information:
FunderGrant number
SYNGENTA AGPO 8700157282
BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC)BB/I003703/1
BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC)Vacation Studentship
BIOTECHNOLOGY AND BIOLOGICAL SCIENCES RESEARCH COUNCIL (BBSRC)BB/D524975/1
Depositing User: Symplectic Sheffield
Date Deposited: 27 Feb 2018 16:25
Last Modified: 24 Oct 2018 10:54
Published Version: https://doi.org/10.1073/pnas.1708839115
Status: Published online
Publisher: National Academy of Sciences
Refereed: Yes
Identification Number: https://doi.org/10.1073/pnas.1708839115
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