Process Analytical Technology (PAT) Aided Identification of Operational Spaces Leading to Tailored Crystal Size Distributions in Azithromycin Crystallization via Coordinated Cooling and Solution Mediated Phase Transition

Tang, XH, Li, Y, Liu, JJ et al. (2 more authors) (2017) Process Analytical Technology (PAT) Aided Identification of Operational Spaces Leading to Tailored Crystal Size Distributions in Azithromycin Crystallization via Coordinated Cooling and Solution Mediated Phase Transition. Organic Process Research and Development, 21 (12). pp. 1963-1971. ISSN 1083-6160

Abstract

Metadata

Authors/Creators:
  • Tang, XH
  • Li, Y
  • Liu, JJ
  • Zhang, Y
  • Wang, XZ
Copyright, Publisher and Additional Information: (c) 2017, American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Process Research and Development, copyright (c) American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see: https://doi.org/10.1021/acs.oprd.7b00238
Keywords: azithromycin crystallization; process analytical technology; tailored crystal size distributions; solvent mediated phase transition; polymorphism; scale-up
Dates:
  • Published: 15 December 2017
  • Accepted: 22 November 2017
  • Published (online): 22 November 2017
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Engineering (Leeds) > School of Chemical & Process Engineering (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 06 Feb 2018 15:56
Last Modified: 22 Nov 2018 01:39
Status: Published
Publisher: American Chemical Society
Identification Number: https://doi.org/10.1021/acs.oprd.7b00238

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