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Low infectiousness of a wildlife host of Leishmania infantum: the crab-eating fox is not important for transmission

Courtenay, O., Quinnell, R.J., Garcez, L.M. and Dye, C. (2002) Low infectiousness of a wildlife host of Leishmania infantum: the crab-eating fox is not important for transmission. Parasitology, 125 (5). pp. 407-414. ISSN 1469-8161

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Abstract

The epidemiological role of the crab-eating fox Cerdocyon thous in the transmission of Leishmania infantum is assessed in a longitudinal study in Amazon Brazil. A total of 37 wild-caught foxes were immunologically and clinically monitored, and 26 foxes exposed to laboratory colonies of the sandfly vector Lutzomyia longipalpis, over a 15-month period. In total 78% (29/37) of foxes were seropositive for anti-Leishmania IgG on at least 1 occasion, and 38% (8/37) had infections confirmed by PCR and/or by culture. Point prevalences were 74% (serology), 15% (PCR), and 26% (culture). No signs of progressive disease were observed. None of the foxes were infectious to the 1469 sandflies dissected from 44 feeds. A conservative estimate of the possible contribution of foxes to transmission was 9% compared to 91% by sympatric domestic dogs. These results show that crab-eating fox populations do not maintain a transmission cycle independently of domestic dogs. The implication is that they are unlikely to introduce the parasite into Leishmania-free dog populations.

Item Type: Article
Copyright, Publisher and Additional Information: © 2002 Cambridge University Press
Keywords: Leishmania infantum, infectiousness, Cerdocyon thous, Brazil, fox
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > Institute of Integrative and Comparative Biology (Leeds)
Depositing User: Repository Officer
Date Deposited: 07 Jun 2006
Last Modified: 06 Jun 2014 19:50
Published Version: http://dx.doi.org/10.1017/S0031182002002238
Status: Published
Publisher: Cambridge University Press
Refereed: Yes
Identification Number: 10.1017/S0031182002002238
URI: http://eprints.whiterose.ac.uk/id/eprint/1261

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