A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells.

Johnston, Chris J. C., Smyth, Danielle J., Kodali, Ravindra B. et al. (18 more authors) (2017) A structurally distinct TGF-β mimic from an intestinal helminth parasite potently induces regulatory T cells. Nature Communications. 1741. ISSN 2041-1723

Abstract

Metadata

Authors/Creators:
  • Johnston, Chris J. C.
  • Smyth, Danielle J.
  • Kodali, Ravindra B.
  • White, Madeleine P. J.
  • Harcus, Yvonne
  • Filbey, Kara J.
  • Hewitson, James Philip ORCID logo https://orcid.org/0000-0002-3265-6763
  • Hinck, Cynthia S.
  • Ivens, Alasdair
  • Kemter, Andrea M.
  • Kildemoes, Anna O.
  • Le Bihan, Thierry
  • Soares, Dinesh C.
  • Anderton, Stephen M.
  • Brenn, Thomas
  • Wigmore, Stephen J.
  • Woodcock, Hannah V.
  • Chambers, Rachel C.
  • Hinck, Andrew P.
  • McSorley, Henry J.
  • Maizels, Rick M.
Copyright, Publisher and Additional Information: © The Author(s) 2017
Keywords: Amino Acid Sequence,Animals,Antigens, Helminth/chemistry,Female,Helminth Proteins/chemistry,Host-Pathogen Interactions/genetics,Humans,Immune Evasion/immunology,Mice,Mice, Inbred BALB C,Mice, Inbred C57BL,Mice, Transgenic,Molecular Mimicry/genetics,Nematospiroides dubius/genetics,Protein Binding,Protein Domains,Receptors, Transforming Growth Factor beta/metabolism,Strongylida Infections/immunology,T-Lymphocytes, Regulatory/immunology,Transforming Growth Factor beta/metabolism,Physics and Astronomy,Chemistry,Biochemistry, Genetics and Molecular Biology
Dates:
  • Published: 23 November 2017
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Biology (York)
Depositing User: Pure (York)
Date Deposited: 27 Nov 2017 10:10
Last Modified: 14 Mar 2021 11:12
Published Version: https://doi.org/10.1038/s41467-017-01886-6
Status: Published
Refereed: Yes
Identification Number: https://doi.org/10.1038/s41467-017-01886-6
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Description: s41467-017-01886-6

Licence: CC-BY 2.5

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