Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain

DiCara, DM, Chirgadze, DY, Pope, AR et al. (12 more authors) (2017) Characterization and structural determination of a new anti-MET function-blocking antibody with binding epitope distinct from the ligand binding domain. Scientific Reports, 7 (1). ARTN 9000. ISSN 2045-2322

Abstract

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Authors/Creators:
  • DiCara, DM
  • Chirgadze, DY
  • Pope, AR
  • Karatt-Vellatt, A
  • Winter, A
  • Slavny, P
  • van den Heuvel, J
  • Parthiban, K
  • Holland, J
  • Packman, LC
  • Mavria, G
  • Hoffmann, J
  • Birchmeier, W
  • Gherardi, E
  • McCafferty, J
Copyright, Publisher and Additional Information: © The Author(s) 2017. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
Keywords: Biologics; cancer; cell migration; X-ray crystallography
Dates:
  • Published: 1 December 2017
  • Accepted: 25 July 2017
  • Published (online): 21 August 2017
Institution: The University of Leeds
Depositing User: Symplectic Publications
Date Deposited: 18 Oct 2017 10:18
Last Modified: 14 Nov 2017 00:21
Status: Published
Publisher: Nature Publishing Group
Identification Number: https://doi.org/10.1038/s41598-017-09460-2
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