Lavender, T., Bedwell, C., Roberts, S.A. et al. (4 more authors) (2013) Randomized, Controlled Trial Evaluating a Baby Wash Product on Skin Barrier Function in Healthy, Term Neonates. Journal of Obstetric, Gynecologic & Neonatal Nursing, 42 (2). pp. 203-214. ISSN 0884-2175
Abstract
Objectives
To examine the hypothesis that the use of a wash product formulated for newborn (<1 month of age) bathing is not inferior (no worse) to bathing with water only.
Design
Assessor‐blinded, randomized, controlled, noninferiority trial.
Setting
A teaching hospital in the Northwest of England and in participants’ homes.
Participants
Three‐hundred‐and‐seven healthy, term infants recruited within 48 hours of birth.
Method
We compared bathing with a wash product (n = 159) to bathing with water alone (n = 148). The primary outcome was transepidermal water loss (TEWL) at 14 days postbirth; the predefined difference deemed to be unimportant was 1.2. Secondary outcomes comprised changes in stratum corneum hydration, skin surface pH, clinical observations of the skin, and maternal views.
Results
Complete TEWL data were obtained for 242 (78.8%) infants. Wash was noninferior to water alone in terms of TEWL (intention‐to‐treat analysis: 95% confidence interval [CI] for difference [wash–water, adjusted for family history of eczema, neonate state, and baseline] −1.24, 1.07; per protocol analysis: 95% CI −1.42, 1.09). No significant differences were found in secondary outcomes.
Conclusion
We were unable to detect any differences between the newborn wash product and water. These findings provide reassurance to parents who choose to use the test newborn wash product or other technically equivalent cleansers and provide the evidence for health care professionals to support parental choice.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2013 AWHONN, the Association of Women's Health, Obstetric and Neonatal Nurses. Published by Elsevier Inc. Available Under a Creative Commons license (https://creativecommons.org/licenses/by/3.0/). |
Keywords: | randomized; term neonates; wash product; neonatal skin care; transepidermal water loss; noninferiority trial |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Infection, Immunity and Cardiovascular Disease The University of Sheffield > Sheffield Teaching Hospitals |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 30 Aug 2017 11:12 |
Last Modified: | 30 Aug 2017 11:16 |
Published Version: | https://doi.org/10.1111/1552-6909.12015 |
Status: | Published |
Publisher: | Elsevier |
Refereed: | Yes |
Identification Number: | 10.1111/1552-6909.12015 |
Related URLs: | |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:120659 |