The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target

Wilkinson, C., McPhillie, M.J., Zhou, Y. et al. (10 more authors) (2014) The benzimidazole based drugs show good activity against T. gondii but poor activity against its proposed enoyl reductase enzyme target. Bioorganic & Medicinal Chemistry Letters, 24 (3). pp. 911-916. ISSN 0960-894X

Abstract

Metadata

Authors/Creators:
  • Wilkinson, C.
  • McPhillie, M.J.
  • Zhou, Y.
  • Woods, S.
  • Afanador, G.A.
  • Rawson, S.
  • Khaliq, F.
  • Prigge, S.T.
  • Roberts, C.W.
  • Rice, D.W.
  • McLeod, R.
  • Fishwick, C.W.
  • Muench, S.P.
Copyright, Publisher and Additional Information: © 2013 The Authors. Published by Elsevier Ltd. Open access under CC-BY license (https://creativecommons.org/licenses/by/3.0/).
Keywords: Enoyl reductase; Triclosan; Toxoplasma; Benzimidazole
Dates:
  • Published: 1 February 2014
  • Published (online): 22 December 2013
  • Accepted: 17 December 2013
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Molecular Biology and Biotechnology (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 27 Jul 2017 11:07
Last Modified: 27 Jul 2017 11:11
Published Version: https://doi.org/10.1016/j.bmcl.2013.12.066
Status: Published
Publisher: Elsevier
Refereed: Yes
Identification Number: https://doi.org/10.1016/j.bmcl.2013.12.066

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