Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices

Pushparajah, DS, Plant, KE, Plant, NJ orcid.org/0000-0003-4332-8308 et al. (1 more author) (2017) Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices. Environmental Toxicology, 32 (3). pp. 764-775. ISSN 1520-4081

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2016 Wiley Periodicals, Inc. This is the peer reviewed version of the following article: Pushparajah, D. S., Plant, K. E., Plant, N. J. and Ioannides, C. (2017), Synergistic and antagonistic interactions of binary mixtures of polycyclic aromatic hydrocarbons in the upregulation of CYP1 activity and mRNA levels in precision-cut rat liver slices. Environ. Toxicol., 32: 764–775. doi:10.1002/tox.22276; which has been published in final form at https://doi.org/10.1002/tox.22276. This article may be used for non-commercial purposes in accordance with the Wiley Terms and Conditions for Self-Archiving.
Keywords: polycyclic aromatic hydrocarbons; cytochrome P450; interactions; risk assessment; precision-cut tissue slices
Dates:
  • Published: March 2017
  • Accepted: 5 April 2016
  • Published (online): 20 April 2016
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 30 Jun 2017 08:31
Last Modified: 07 Feb 2018 08:47
Status: Published
Publisher: Wiley
Identification Number: https://doi.org/10.1002/tox.22276

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