Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site

Exell, JC, Thompson, MJ, Finger, LD et al. (11 more authors) (2016) Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site. Nature Chemical Biology, 12 (10). pp. 815-821. ISSN 1552-4450

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Copyright, Publisher and Additional Information: © 2016 Nature America, Inc. This is an author produced version of a paper published in Nature Chemical Biology. Uploaded in accordance with the publisher's self-archiving policy.
Keywords: DNA damage and repair; Enzyme mechanisms; Small molecules; X-ray crystallography
Dates:
  • Published: 15 August 2016
  • Accepted: 19 May 2016
  • Published (online): 15 August 2016
Institution: The University of Leeds
Depositing User: Symplectic Publications
Date Deposited: 26 Jun 2017 09:52
Last Modified: 17 Feb 2018 00:41
Status: Published
Publisher: Nature Publishing Group
Identification Number: https://doi.org/10.1038/nchembio.2148

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