Rowen, D.L. orcid.org/0000-0003-3018-5109, Brazier, J., Ara, R. et al. (1 more author) (2017) The Role Of Condition-Specific Preference-Based Measures In Health Technology Assessment. PharmacoEconomics, 35 (Suppl 1). pp. 33-41. ISSN 1170-7690
Abstract
A condition-specific preference-based measure (CSPBM) is a measure of health related quality of life (HRQoL) that is specific to a certain condition or disease and that can be used to obtain the quality adjustment weight of the quality adjusted life year (QALY) for use in economic models. This article provides an overview of the role of CSPBMs, the development of CSPBMs, and presents a description of existing CSPBMs in the literature. The article also provides an overview of the psychometric properties of CSPBMs in comparison to generic preference-based measures (generic PBMs), and considers the advantages and disadvantages of CSPBMs in comparison to generic PBMs.
CSPBMs typically include dimensions that are important for that condition but may not be important across all patient groups. There are a large number of CSPBMs across a wide range of conditions, and these vary from covering a wide range of dimensions to more symptomatic or uni-dimensional measures. Psychometric evidence is limited but suggests that CSPBMs offer an advantage in more accurate measurement of milder health states. The mean change and standard deviation can differ for CSPBMs and generic PBMs, and this may impact on incremental cost-effectiveness ratios.
CSPBMs have a useful role in HTA where a generic PBM is not appropriate, sensitive or responsive. However due to issues of comparability across different patient groups and interventions, their usage in health technology assessment is often limited to conditions where it is inappropriate to use a generic PBM or sensitivity analyses.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © Springer International Publishing AG 2017. This is an author produced version of a paper subsequently published in PharmacoEconomics. Uploaded in accordance with the publisher's self-archiving policy. |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 11 Jul 2017 13:10 |
Last Modified: | 19 Oct 2018 00:39 |
Published Version: | https://doi.org/10.1007/s40273-017-0546-9 |
Status: | Published |
Publisher: | Springer International Publishing |
Refereed: | Yes |
Identification Number: | 10.1007/s40273-017-0546-9 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:118044 |