SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits

Hautbergue, G.M. orcid.org/0000-0002-1621-261X, Castelli, L.M., Ferraiuolo, L. et al. (23 more authors) (2017) SRSF1-dependent nuclear export inhibition of C9ORF72 repeat transcripts prevents neurodegeneration and associated motor deficits. Nature Communications, 8. 16063 (2017).

Abstract

Metadata

Authors/Creators:
  • Hautbergue, G.M. https://orcid.org/0000-0002-1621-261X
  • Castelli, L.M.
  • Ferraiuolo, L.
  • Sanchez-Martinez, A.
  • Cooper-Knock, J.
  • Higginbottom, A.
  • Lin, Y.H.
  • Bauer, C.S.
  • Dodd, J.E.
  • Myszczynska, M.A.
  • Alam, S.M.
  • Garneret, P.
  • Chandran, J.S.
  • Karyka, E.
  • Stopford, M.J.
  • Smith, E.F.
  • Kirby, J.
  • Meyer, K.
  • Kaspar, B.K.
  • Isaacs, A.M.
  • El-Khamisy, S.F.
  • De Vos, K.J.
  • Ning, K.
  • Azzouz, M.
  • Whitworth, A.J.
  • Shaw, P.J.
Copyright, Publisher and Additional Information: © The Author(s) 2017. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit (http://creativecommons.org/licenses/by/4.0/)
Dates:
  • Accepted: 24 May 2017
  • Published: 5 July 2017
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Neuroscience (Sheffield)
The University of Sheffield > Sheffield Teaching Hospitals
Funding Information:
FunderGrant number
ROYAL SOCIETYRG140690
EUROPEAN RESEARCH COUNCILGTNCTV - 294745
SHEFFIELD HOSPITALS CHARITABLE TRUST121340/2
MOTOR NEURONE DISEASE ASSOCIATIONHautberge/Mar16/900-790
MEDICAL RESEARCH COUNCILMR/M010864/1
MEDICAL RESEARCH COUNCILMR/M013251/1
MEDICAL RESEARCH COUNCILMR/K003771/1
EUROPEAN COMMISSION - FP6/FP7EUROMOTOR - 259867
MEDICAL RESEARCH COUNCILMR/K005146/1
MOTOR NEURONE DISEASE ASSOCIATIONMND005891
THIERRY LATRAN FOUNDATIONFTL AAP 2016
Depositing User: Symplectic Sheffield
Date Deposited: 02 Jun 2017 12:53
Last Modified: 30 Oct 2018 11:47
Published Version: https://doi.org/10.1038/ncomms16063
Status: Published
Publisher: Nature Publishing Group
Refereed: Yes
Identification Number: https://doi.org/10.1038/ncomms16063

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