Dalton, M, Finlayson, G orcid.org/0000-0002-5620-2256, Walsh, B et al. (3 more authors) (2017) Early improvement in food cravings are associated with long-term weight loss success in a large clinical sample. International Journal of Obesity, 41 (8). pp. 1232-1236. ISSN 0307-0565
Abstract
Background:
Food cravings are associated with dysregulated eating behaviour and obesity, and may impede successful weight loss attempts. Gaining control over food craving is therefore a component in the management of obesity. The current paper examined whether early changes in control over food craving (assessed using the Craving Control subscale on the Control of Eating Questionnaire (CoEQ)) was predictive of weight loss in four phase 3 clinical trials investigating a sustained-release combination of naltrexone/bupropion (NB) in obese adults. The underlying component structure of the CoEQ was also examined.
Method:
In an integrated analysis of four 56-week phase 3 clinical trials, subjects completed the CoEQ and had their body weight measured at baseline and at weeks 8, 16, 28 and 56. All analyses were conducted on subjects who had complete weight and CoEQ measurements at baseline and week 56, and had completed 56 weeks of NB (n=1310) or placebo (n=736). A latent growth curve model was used to examine whether early changes in the CoEQ subscales were associated with decreases in weight loss over time. Confirmatory factor analysis (CFA) was used to determine the psychometric properties of the CoEQ.
Results:
The factor structure of the CoEQ was consistent with previous findings with a four-factor solution being confirmed: Craving Control, Positive Mood, Craving for Sweet and Craving for Savoury with good internal consistency (Cronbach’s α=0.72–0.92). Subjects with the greatest improvement in Craving Control at week 8 exhibited a greater weight loss at week 56.
Conclusions:
These findings highlight the importance of the experience of food cravings in the treatment of obesity and support the use of the CoEQ as a psychometric tool for the measurement of food cravings in research and the pharmacological management of obesity.
Metadata
Item Type: | Article |
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Authors/Creators: |
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Copyright, Publisher and Additional Information: | © The Author(s) 2017. This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
Keywords: | Risk factors; Weight management |
Dates: |
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Institution: | The University of Leeds |
Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Psychology (Leeds) |
Depositing User: | Symplectic Publications |
Date Deposited: | 04 May 2017 09:07 |
Last Modified: | 26 Jun 2019 19:12 |
Status: | Published |
Publisher: | Nature Publishing Group |
Identification Number: | 10.1038/ijo.2017.89 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:115987 |
Commentary/Response Threads
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Dalton, M, Finlayson, G, Walsh, B, Halseth, AE, Duarte, C and Blundell, JE
Early improvement in food cravings are associated with long-term weight loss success in a large clinical sample. (deposited 04 May 2017 09:07)
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- Dalton, M, Finlayson, G, Walsh, B, Halseth, AE, Duarte, C and Blundell, JE Early improvement in food cravings are associated with long-term weight loss success in a large clinical sample. (deposited 11 Jun 2019 08:35)