Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk.

Day, F.R., Thompson, D.J., Helgason, H. et al. (219 more authors) (2017) Genomic analyses identify hundreds of variants associated with age at menarche and support a role for puberty timing in cancer risk. Nature Genetics. ISSN 1061-4036

Abstract

Metadata

Authors/Creators:
  • Day, F.R.
  • Thompson, D.J.
  • Helgason, H.
  • Chasman, D.I.
  • Finucane, H.
  • Sulem, P.
  • Ruth, K.S.
  • Whalen, S.
  • Sarkar, A.K.
  • Albrecht, E.
  • Altmaier, E.
  • Amini, M.
  • Barbieri, C.M.
  • Boutin, T.
  • Campbell, A.
  • Demerath, E.
  • Giri, A.
  • He, C.
  • Hottenga, J.J.
  • Karlsson, R.
  • Kolcic, I.
  • Loh, P.-R.
  • Lunetta, K.L.
  • Mangino, M.
  • Marco, B.
  • McMahon, G.
  • Medland, S.E.
  • Nolte, I.M.
  • Noordam, R.
  • Nutile, T.
  • Paternoster, L.
  • Perjakova, N.
  • Porcu, E.
  • Rose, L.M.
  • Schraut, K.E.
  • Segrè, A.V.
  • Smith, A.V.
  • Stolk, L.
  • Teumer, A.
  • Andrulis, I.L.
  • Bandinelli, S.
  • Beckmann, M.W.
  • Benitez, J.
  • Bergmann, S.
  • Bochud, M.
  • Boerwinkle, E.
  • Bojesen, S.E.
  • Bolla, M.K.
  • Brand, J.S.
  • Brauch, H.
  • Brenner, H.
  • Broer, L.
  • Brüning, T.
  • Buring, J.E.
  • Campbell, H.
  • Catamo, E.
  • Chanock, S.
  • Chenevix-Trench, G.
  • Corre, T.
  • Couch, F.J.
  • Cousminer, D.L.
  • Cox, A.
  • Crisponi, L.
  • Czene, K.
  • Davey Smith, G.
  • de Geus, E.J.C.N.
  • de Mutsert, R.
  • De Vivo, I.
  • Dennis, J.
  • Devilee, P.
  • Dos-Santos-Silva, I.
  • Dunning, A.M.
  • Eriksson, J.G.
  • Fasching, P.A.
  • Fernández-Rhodes, L.
  • Ferrucci, L.
  • Flesch-Janys, D.
  • Franke, L.
  • Gabrielson, M.
  • Gandin, I.
  • Giles, G.G.
  • Grallert, H.
  • Gudbjartsson, D.F.
  • Guénel, P.
  • Hall, P.
  • Hallberg, E.
  • Hamann, U.
  • Harris, T.B.
  • Hartman, C.A.
  • Heiss, G.
  • Hooning, M.J.
  • Hopper, J.L.
  • Hu, F.
  • Hunter, D.J.
  • Ikram, M.A.
  • Im, H.K.
  • Järvelin, M.-R.
  • Joshi, P.K.
  • Karasik, D.
  • Kellis, M.
  • Kutalik, Z.
  • LaChance, G.
  • Lambrechts, D.
  • Langenberg, C.
  • Launer, L.J.
  • Laven, J.S.E.
  • Lenarduzzi, S.
  • Li, J.
  • Lind, P.A.
  • Lindstrom, S.
  • Liu, Y.
  • Luan, J.
  • Mägi, R.
  • Mannermaa, A.
  • Mbarek, H.
  • McCarthy, M.I.
  • Meisinger, C.
  • Meitinger, T.
  • Menni, C.
  • Metspalu, A.
  • Michailidou, K.
  • Milani, L.
  • Milne, R.L.
  • Montgomery, G.W.
  • Mulligan, A.M.
  • Nalls, M.A.
  • Navarro, P.
  • Nevanlinna, H.
  • Nyholt, D.R.
  • Oldehinkel, A.J.
  • O'Mara, T.A.
  • Padmanabhan, S.
  • Palotie, A.
  • Pedersen, N.
  • Peters, A.
  • Peto, J.
  • Pharoah, P.D.P.
  • Pouta, A.
  • Radice, P.
  • Rahman, I.
  • Ring, S.M.
  • Robino, A.
  • Rosendaal, F.R.
  • Rudan, I.
  • Rueedi, R.
  • Ruggiero, D.
  • Sala, C.F.
  • Schmidt, M.K.
  • Scott, R.A.
  • Shah, M.
  • Sorice, R.
  • Southey, M.C.
  • Sovio, U.
  • Stampfer, M.
  • Steri, M.
  • Strauch, K.
  • Tanaka, T.
  • Tikkanen, E.
  • Timpson, N.J.
  • Traglia, M.
  • Truong, T.
  • Tyrer, J.P.
  • Uitterlinden, A.G.
  • Edwards, D.R.V.
  • Vitart, V.
  • Völker, U.
  • Vollenweider, P.
  • Wang, Q.
  • Widen, E.
  • van Dijk, K.W.
  • Willemsen, G.
  • Winqvist, R.
  • Wolffenbuttel, B.H.R.
  • Zhao, J.H.
  • Zoledziewska, M.
  • Zygmunt, M.
  • Alizadeh, B.Z.
  • Boomsma, D.I.
  • Ciullo, M.
  • Cucca, F.
  • Esko, T.
  • Franceschini, N.
  • Gieger, C.
  • Gudnason, V.
  • Hayward, C.
  • Kraft, P.
  • Lawlor, D.A.
  • Magnusson, P.K.E.
  • Martin, N.G.
  • Mook-Kanamori, D.O.
  • Nohr, E.A.
  • Polasek, O.
  • Porteous, D.
  • Price, A.L.
  • Ridker, P.M.
  • Snieder, H.
  • Spector, T.D.
  • Stöckl, D.
  • Toniolo, D.
  • Ulivi, S.
  • Visser, J.A.
  • Völzke, H.
  • Wareham, N.J.
  • Wilson, J.F.
  • LifeLines Cohort Study,
  • InterAct Consortium,
  • kConFab/AOCS Investigators,
  • Endometrial Cancer Association Consortium,
  • Ovarian Cancer Association Consortium,
  • PRACTICAL Consortium,
  • Spurdle, A.B.
  • Thorsteindottir, U.
  • Pollard, K.S.
  • Easton, D.F.
  • Tung, J.Y.
  • Chang-Claude, J.
  • Hinds, D.
  • Murray, A.
  • Murabito, J.M.
  • Stefansson, K.
  • Ong, K.K.
  • Perry, J.R.B.
Copyright, Publisher and Additional Information: © 2017 Nature America, Inc., part of Springer Nature. This is an author produced version of a paper subsequently published in Nature Genetics. Uploaded in accordance with the publisher's self-archiving policy.
Keywords: Cancer; Genome-wide association studies; Reproductive disorders
Dates:
  • Published (online): 24 April 2017
  • Accepted: 17 March 2017
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology (Sheffield)
Funding Information:
FunderGrant number
BREAST CANCER NOWUNSPECIFIED
CANCER RESEARCH UK (CRUK)C9267/A25152
Depositing User: Symplectic Sheffield
Date Deposited: 03 May 2017 14:26
Last Modified: 25 Oct 2017 14:06
Published Version: https://doi.org/10.1038/ng.3841
Status: Published online
Publisher: Nature Publishing Group
Refereed: Yes
Identification Number: https://doi.org/10.1038/ng.3841
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