Enhanced H2AX Phosphorylation, DNA Replication Fork Arrest, and Cell Death in the Absence of Chk1

Gagou, M.E., Zuazua-Villar, P. and Meuth, M. (2010) Enhanced H2AX Phosphorylation, DNA Replication Fork Arrest, and Cell Death in the Absence of Chk1. Molecular Biology of the Cell , 21 (5). pp. 739-752. ISSN 1059-1524

Abstract

Metadata

Authors/Creators:
  • Gagou, M.E.
  • Zuazua-Villar, P.
  • Meuth, M.
Copyright, Publisher and Additional Information: © 2010 by The American Society for Cell Biology. Reproduced in accordance with the publisher's self-archiving policy.
Keywords: DOUBLE-STRAND BREAKS; S-PHASE CHECKPOINT; HISTONE H2AX; TOPOISOMERASE-I; GINS COMPLEX; TUMOR-CELLS; SERINE 139; REPAIR; ATR; ACTIVATION
Dates:
  • Published: 1 March 2010
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology and Metabolism (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 18 May 2017 09:13
Last Modified: 18 May 2017 09:13
Published Version: https://doi.org/10.1091/mbc.E09-07-0618
Status: Published
Publisher: American Society for Cell Biology
Refereed: Yes
Identification Number: https://doi.org/10.1091/mbc.E09-07-0618

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