Comparison of a Batch and Flow Approach for the Lipase-Catalyzed Resolution of a Cyclopropanecarboxylate Ester, A Key Building Block for the Synthesis of Ticagrelor

Hugentobler, KG, Rasparini, M, Thompson, LA orcid.org/0000-0003-1128-7927 et al. (3 more authors) (2017) Comparison of a Batch and Flow Approach for the Lipase-Catalyzed Resolution of a Cyclopropanecarboxylate Ester, A Key Building Block for the Synthesis of Ticagrelor. Organic Process Research and Development, 21 (2). pp. 195-199. ISSN 1083-6160

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Copyright, Publisher and Additional Information: © 2016 American Chemical Society. This document is the Accepted Manuscript version of a Published Work that appeared in final form in Organic Process Research and Development, copyright © American Chemical Society after peer review and technical editing by the publisher. To access the final edited and published work see https://doi.org/10.1021/acs.oprd.6b00346. Uploaded in accordance with the publisher's self-archiving policy.
Keywords: batch reactor; enzyme catalysis; flow chemistry; Thermomyces lanuginosus lipase; ticagrelor
Dates:
  • Published: 2017
  • Accepted: 22 December 2016
  • Published (online): 22 December 2016
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Maths and Physical Sciences (Leeds) > School of Chemistry (Leeds) > Organic Chemistry (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 02 Feb 2017 10:53
Last Modified: 22 Dec 2017 01:38
Published Version: https://doi.org/10.1021/acs.oprd.6b00346
Status: Published
Publisher: American Chemical Society
Identification Number: https://doi.org/10.1021/acs.oprd.6b00346

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