Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy.

Abbotts, R, Jewell, R, Nsengimana, J et al. (13 more authors) (2014) Targeting human apurinic/apyrimidinic endonuclease 1 (APE1) in phosphatase and tensin homolog (PTEN) deficient melanoma cells for personalized therapy. Oncotarget, 5 (10). pp. 3273-3286. ISSN 1949-2553

Abstract

Metadata

Authors/Creators:
  • Abbotts, R
  • Jewell, R
  • Nsengimana, J
  • Maloney, DJ
  • Simeonov, A
  • Seedhouse, C
  • Elliott, F
  • Laye, J
  • Walker, C
  • Jadhav, A
  • Grabowska, A
  • Ball, G
  • Patel, PM
  • Newton-Bishop, J
  • Wilson, DM
  • Madhusudan, S
Copyright, Publisher and Additional Information: © 2014, The Author(s). This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Keywords: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Comet Assay; DNA-(Apurinic or Apyrimidinic Site) Lyase; Flow Cytometry; Gene Knockdown Techniques; Genome-Wide Association Study; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Melanoma; Molecular Targeted Therapy; PTEN Phosphohydrolase; RNA, Messenger; Real-Time Polymerase Chain Reaction; Transfection
Dates:
  • Published: 30 May 2014
  • Accepted: 25 April 2014
  • Published (online): 27 April 2014
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Medicine and Health (Leeds) > Institute of Molecular Medicine (LIMM) (Leeds) > Section of Epidemiology and Biostatistics (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 24 Mar 2017 15:43
Last Modified: 24 Mar 2017 15:43
Published Version: https://doi.org/10.18632/oncotarget.1926
Status: Published
Publisher: Impact Journals
Identification Number: https://doi.org/10.18632/oncotarget.1926
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