Maternal gestational vitamin D supplementation and offspring bone health (MAVIDOS): a multicentre, double-blind, randomised placebo-controlled trial

Abstract

Maternal vitamin D status has been associated with bone mass of offspring in many, but not all, observational studies. However, maternal vitamin D repletion during pregnancy has not yet been proven to improve offspring bone mass in a randomised controlled trial. We aimed to assess whether neonates born to mothers supplemented with vitamin D during pregnancy have greater whole-body bone mineral content (BMC) at birth than those of mothers who had not received supplementation.

Metadata

Authors/Creators:

Cooper, C.
Harvey, N.C.
Bishop, N.J. https://orcid.org/0000-0001-7263-8546
Kennedy, S.
Papageorghiou, A.T.
Schoenmakers, I.
Fraser, R.
Gandhi, S.V.
Carr, A.
D'Angelo, S.
Crozier, S.R.
Moon, R.J.
Arden, N.K.
Dennison, E.M.
Godfrey, K.M.
Inskip, H.M.
Prentice, A.
Mughal, M.Z.
Eastell, R. https://orcid.org/0000-0002-0323-3366
Reid, D.M.
Javaid, M.K.

© 2016 Elsevier. This is an author produced version of a paper subsequently published in The Lancet Diabetes and Endocrinology. Uploaded in accordance with the publisher's self-archiving policy. Article available under the terms of the CC-BY-NC-ND licence (https://creativecommons.org/licenses/by-nc-nd/4.0/)

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