Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis.

Mellone, M., Hanley, C.J., Thirdborough, S. et al. (24 more authors) (2016) Induction of fibroblast senescence generates a non-fibrogenic myofibroblast phenotype that differentially impacts on cancer prognosis. Aging.

Abstract

Metadata

Authors/Creators:
  • Mellone, M.
  • Hanley, C.J.
  • Thirdborough, S.
  • Mellows, T.
  • Garcia, E.
  • Woo, J.
  • Tod, J.
  • Frampton, S.
  • Jenei, V.
  • Moutasim, K.A.
  • Kabir, T.D.
  • Brennan, P.A.
  • Venturi, G.
  • Ford, K.
  • Herranz, N.
  • Lim, K.P.
  • Clarke, J.
  • Lambert, D.W. https://orcid.org/0000-0001-9003-3145
  • Prime, S.S.
  • Underwood, T.J.
  • Vijayanand, P.
  • Eliceiri, K.W.
  • Woelk, C.
  • King, E.V.
  • Gil, J.
  • Ottensmeier, C.H.
  • Thomas, G.J.
Copyright, Publisher and Additional Information: © 2016 The Author(s). AGING applies the Creative Commons Attribution License (CC BY) to all works we publish. Under the CC BY, authors retain ownership of the copyright for their article, but authors allow anyone to download, reuse, reprint, modify, distribute, and/or copy articles in Aging journal, so long as the original authors and source are cited.
Keywords: collagen; extracellular matrix; myofibroblasts; senescence; senescent fibroblasts; tumor microenvironment
Dates:
  • Published: 15 December 2016
  • Accepted: 29 November 2016
  • Published (online): 15 December 2016
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Dentistry (Sheffield)
Depositing User: Symplectic Sheffield
Date Deposited: 16 Jan 2017 16:30
Last Modified: 16 Jan 2017 16:30
Published Version: http://doi.org/10.18632/aging.101127
Status: Published
Publisher: Impact Journals
Refereed: Yes
Identification Number: https://doi.org/10.18632/aging.101127
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