New genetic loci link adipose and insulin biology to body fat distribution.

Shungin, D, Winkler, TW, Croteau-Chonka, DC et al. (416 more authors) (2015) New genetic loci link adipose and insulin biology to body fat distribution. Nature, 518 (7538). pp. 187-196. ISSN 0028-0836

Abstract

Metadata

Authors/Creators:
  • Shungin, D
  • Winkler, TW
  • Croteau-Chonka, DC
  • Ferreira, T
  • Locke, AE
  • Mägi, R
  • Strawbridge, RJ
  • Pers, TH
  • Fischer, K
  • Justice, AE
  • Workalemahu, T
  • Wu, JM
  • Buchkovich, ML
  • Heard-Costa, NL
  • Roman, TS
  • Drong, AW
  • Song, C
  • Gustafsson, S
  • Day, FR
  • Esko, T
  • Fall, T
  • Kutalik, Z
  • Luan, J
  • Randall, JC
  • Scherag, A
  • Vedantam, S
  • Wood, AR
  • Chen, J
  • Fehrmann, R
  • Karjalainen, J
  • Kahali, B
  • Liu, CT
  • Schmidt, EM
  • Absher, D
  • Amin, N
  • Anderson, D
  • Beekman, M
  • Bragg-Gresham, JL
  • Buyske, S
  • Demirkan, A
  • Ehret, GB
  • Feitosa, MF
  • Goel, A
  • Jackson, AU
  • Johnson, T
  • Kleber, ME
  • Kristiansson, K
  • Mangino, M
  • Mateo Leach, I
  • Medina-Gomez, C
  • Palmer, CD
  • Pasko, D
  • Pechlivanis, S
  • Peters, MJ
  • Prokopenko, I
  • Stančáková, A
  • Ju Sung, Y
  • Tanaka, T
  • Teumer, A
  • Van Vliet-Ostaptchouk, JV
  • Yengo, L
  • Zhang, W
  • Albrecht, E
  • Ärnlöv, J
  • Arscott, GM
  • Bandinelli, S
  • Barrett, A
  • Bellis, C
  • Bennett, AJ
  • Berne, C
  • Blüher, M
  • Böhringer, S
  • Bonnet, F
  • Böttcher, Y
  • Bruinenberg, M
  • Carba, DB
  • Caspersen, IH
  • Clarke, R
  • Daw, EW
  • Deelen, J
  • Deelman, E
  • Delgado, G
  • Doney, AS
  • Eklund, N
  • Erdos, MR
  • Estrada, K
  • Eury, E
  • Friedrich, N
  • Garcia, ME
  • Giedraitis, V
  • Gigante, B
  • Go, AS
  • Golay, A
  • Grallert, H
  • Grammer, TB
  • Gräßler, J
  • Grewal, J
  • Groves, CJ
  • Haller, T
  • Hallmans, G
  • Hartman, CA
  • Hassinen, M
  • Hayward, C
  • Heikkilä, K
  • Herzig, KH
  • Helmer, Q
  • Hillege, HL
  • Holmen, O
  • Hunt, SC
  • Isaacs, A
  • Ittermann, T
  • James, AL
  • Johansson, I
  • Juliusdottir, T
  • Kalafati, IP
  • Kinnunen, L
  • Koenig, W
  • Kooner, IK
  • Kratzer, W
  • Lamina, C
  • Leander, K
  • Lee, NR
  • Lichtner, P
  • Lind, L
  • Lindström, J
  • Lobbens, S
  • Lorentzon, M
  • Mach, F
  • Magnusson, PK
  • Mahajan, A
  • McArdle, WL
  • Menni, C
  • Merger, S
  • Mihailov, E
  • Milani, L
  • Mills, R
  • Moayyeri, A
  • Monda, KL
  • Mooijaart, SP
  • Mühleisen, TW
  • Mulas, A
  • Müller, G
  • Müller-Nurasyid, M
  • Nagaraja, R
  • Nalls, MA
  • Narisu, N
  • Glorioso, N
  • Nolte, IM
  • Olden, M
  • Rayner, NW
  • Renstrom, F
  • Ried, JS
  • Robertson, NR
  • Rose, LM
  • Sanna, S
  • Scharnagl, H
  • Scholtens, S
  • Sennblad, B
  • Seufferlein, T
  • Sitlani, CM
  • Vernon Smith, A
  • Stirrups, K
  • Stringham, HM
  • Sundström, J
  • Swertz, MA
  • Swift, AJ
  • Syvänen, AC
  • Tayo, BO
  • Thorand, B
  • Thorleifsson, G
  • Tomaschitz, A
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  • van Oort, FV
  • Verweij, N
  • Vonk, JM
  • Waite, LL
  • Wennauer, R
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  • Wojczynski, MK
  • Wong, A
  • Zhang, Q
  • Hua Zhao, J
  • Brennan, EP
  • Choi, M
  • Eriksson, P
  • Folkersen, L
  • Franco-Cereceda, A
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  • Hedman, ÅK
  • Hivert, MF
  • Huang, J
  • Kanoni, S
  • Karpe, F
  • Keildson, S
  • Kiryluk, K
  • Liang, L
  • Lifton, RP
  • Ma, B
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  • Min, JL
  • Moffatt, MF
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  • Murabito, JM
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  • Nyholt, DR
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  • Reinmaa, E
  • Salem, RM
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  • Schadt, EE
  • Scott, RA
  • Stolk, L
  • Vallejo, EE
  • Westra, HJ
  • Zondervan, KT
  • ADIPOGen Consortium,
  • CARDIOGRAMplusC4D Consortium,
  • CKDGen Consortium,
  • GEFOS Consortium,
  • GENIE Consortium,
  • GLGC,
  • ICBP,
  • International Endogene Consortium,
  • LifeLines Cohort Study,
  • MAGIC Investigators,
  • MuTHER Consortium,
  • PAGE Consortium,
  • ReproGen Consortium,
  • Amouyel, P
  • Arveiler, D
  • Bakker, SJ
  • Beilby, J
  • Bergman, RN
  • Blangero, J
  • Brown, MJ
  • Burnier, M
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  • Collins, FS
  • Crawford, DC
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  • Erbel, R
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  • Farrall, M
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  • Ferrières, J
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  • Franco, OH
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  • Hicks, AA
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  • Illig, T
  • Jarvelin, MR
  • Johansen, B
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  • Kaprio, J
  • Kee, F
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  • Kooner, JS
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  • Kovacs, P
  • Kraja, AT
  • Kumari, M
  • Kuulasmaa, K
  • Kuusisto, J
  • Lakka, TA
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  • Lehtimäki, T
  • Lyssenko, V
  • Männistö, S
  • Marette, A
  • Matise, TC
  • McKenzie, CA
  • McKnight, B
  • Musk, AW
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  • Morris, AD
  • Nelis, M
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  • Oldehinkel, AJ
  • Ong, KK
  • Palmer, LJ
  • Penninx, BW
  • Peters, A
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  • Rankinen, T
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  • Rice, TK
  • Ridker, PM
  • Ritchie, MD
  • Rudan, I
  • Salomaa, V
  • Samani, NJ
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  • Sarzynski, MA
  • Schwarz, PE
  • Shuldiner, AR
  • Staessen, JA
  • Steinthorsdottir, V
  • Stolk, RP
  • Strauch, K
  • Tönjes, A
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  • Tremoli, E
  • Vohl, MC
  • Völker, U
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  • Wilson, JF
  • Witteman, JC
  • Adair, LS
  • Bochud, M
  • Boehm, BO
  • Bornstein, SR
  • Bouchard, C
  • Cauchi, S
  • Caulfield, MJ
  • Chambers, JC
  • Chasman, DI
  • Cooper, RS
  • Dedoussis, G
  • Ferrucci, L
  • Froguel, P
  • Grabe, HJ
  • Hamsten, A
  • Hui, J
  • Hveem, K
  • Jöckel, KH
  • Kivimaki, M
  • Kuh, D
  • Laakso, M
  • Liu, Y
  • März, W
  • Munroe, PB
  • Njølstad, I
  • Oostra, BA
  • Palmer, CN
  • Pedersen, NL
  • Perola, M
  • Pérusse, L
  • Peters, U
  • Power, C
  • Quertermous, T
  • Rauramaa, R
  • Rivadeneira, F
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  • Sinisalo, J
  • Slagboom, PE
  • Snieder, H
  • Spector, TD
  • Thorsteinsdottir, U
  • Stumvoll, M
  • Tuomilehto, J
  • Uitterlinden, AG
  • Uusitupa, M
  • van der Harst, P
  • Veronesi, G
  • Walker, M
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  • Watkins, H
  • Wichmann, HE
  • Abecasis, GR
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  • Boehnke, M
  • Borecki, IB
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  • Franke, L
  • Frayling, TM
  • Groop, LC
  • Hunter, DJ
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  • Qi, L
  • Schlessinger, D
  • Strachan, DP
  • Stefansson, K
  • van Duijn, CM
  • Willer, CJ
  • Visscher, PM
  • Yang, J
  • Hirschhorn, JN
  • Zillikens, MC
  • McCarthy, MI
  • Speliotes, EK
  • North, KE
  • Fox, CS
  • Barroso, I
  • Franks, PW
  • Ingelsson, E
  • Heid, IM
  • Loos, RJ
  • Cupples, LA
  • Morris, AP
  • Lindgren, CM
  • Mohlke, KL
Copyright, Publisher and Additional Information: © 2015 Nature Publishing Group. This is an author produced version of a paper subsequently published in Nature . Uploaded in accordance with the publisher's self-archiving policy.
Keywords: Adipocytes; Adipogenesis; Adipose Tissue; Age Factors; Body Fat Distribution; Body Mass Index; Continental Population Groups; Epigenesis, Genetic; Europe; Female; Genome, Human; Genome-Wide Association Study; Humans; Insulin; Insulin Resistance; Male; Models, Biological; Neovascularization, Physiologic; Obesity; Polymorphism, Single Nucleotide; Quantitative Trait Loci; Sex Characteristics; Transcription, Genetic; Waist-Hip Ratio
Dates:
  • Published: 12 February 2015
  • Accepted: 2 December 2014
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Medicine (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology (Sheffield)
The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 09 Dec 2016 16:33
Last Modified: 03 Apr 2018 13:58
Published Version: https://doi.org/10.1038/nature14132
Status: Published
Publisher: Nature Publishing Group
Refereed: Yes
Identification Number: https://doi.org/10.1038/nature14132
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