Menakuru, S.R., Brown, N.J. orcid.org/0000-0002-2100-1905, Staton, C.A. et al. (1 more author) (2008) Angiogenesis in pre-malignant conditions. British Journal of Cancer, 99 (12). pp. 1961-1966. ISSN 0007-0920
Abstract
Evidence from human studies suggests that angiogenesis commences during the pre-malignant stages of cancer. Inhibiting angiogenesis may, therefore, be of potential value in preventing progression to invasive cancer. Understanding the mechanisms inducing angiogenesis in these lesions and identification of those important in human tumourigenesis are necessary to develop translational strategies that will help realise the goal of angioprevention.
Metadata
Item Type: | Article |
---|---|
Authors/Creators: |
|
Copyright, Publisher and Additional Information: | © 2008 Cancer Research UK. This work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/ |
Keywords: | angiogenesis; microvessel density; pre-malignant; carcinogenesis; endothelial growth-factor; squamous-cell carcinoma; cervical intraepithelial neoplasia; nitric-oxide synthase; nf-kappa-b; factor expression; tumor angiogenesis; switch occurs; in-vivo; cancer |
Dates: |
|
Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > The Medical School (Sheffield) > Division of Genomic Medicine (Sheffield) > Department of Oncology and Metabolism (Sheffield) The University of Sheffield > Sheffield Teaching Hospitals |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 13 Dec 2016 09:44 |
Last Modified: | 13 Dec 2016 09:44 |
Published Version: | http://dx.doi.org/10.1038/sj.bjc.6604733 |
Status: | Published |
Publisher: | Cancer Research UK |
Refereed: | Yes |
Identification Number: | 10.1038/sj.bjc.6604733 |
Open Archives Initiative ID (OAI ID): | oai:eprints.whiterose.ac.uk:107795 |
Download
Filename: Angiogenesis in pre-malignant conditions.pdf
Licence: CC-BY-NC-SA 3.0