Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin.

Atteya, R., Ashour, M.E., Ibrahim, E.E. et al. (2 more authors) (2017) Chemical screening identifies the β-Carboline alkaloid harmine to be synergistically lethal with doxorubicin. Mechanisms of Ageing and Development, 161 (A). pp. 141-148. ISSN 0047-6374

Abstract

Metadata

Authors/Creators:
Copyright, Publisher and Additional Information: © 2016 The Author(s). Published by Elsevier Ireland Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/)
Keywords: Cardiotoxicity; DYRK1A kinase; Doxorubicin; Harmine; Natural products; TOP2
Dates:
  • Published (online): 6 June 2016
  • Accepted: 30 April 2016
  • Published: January 2017
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Faculty of Science (Sheffield) > School of Biological Sciences (Sheffield) > Department of Molecular Biology and Biotechnology (Sheffield)
Funding Information:
FunderGrant number
BRITISH COUNCIL (THE)171964603
LISTER INSTITUTE OF PREVENTATIVE MEDICINENONE
WELLCOME TRUST (THE)103844/Z/14/Z
Depositing User: Symplectic Sheffield
Date Deposited: 05 Jul 2016 12:01
Last Modified: 28 Jun 2017 13:58
Published Version: http://dx.doi.org/10.1016/j.mad.2016.04.012
Status: Published
Publisher: Elsevier
Refereed: Yes
Identification Number: https://doi.org/10.1016/j.mad.2016.04.012
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