Terry, R.S., Dunn, A.M. and Smith, J.E. (1999) Segregation of a microsporidian parasite during host cell mitosis. Parasitology, 118 (1). pp. 43-48. ISSN 1469-8161
Available under licence : See the attached licence file.
We investigated the segregation of an intracellular microsporidian parasite during host cell division. A time-course experiment was carried out to examine the distribution of parasites relative to host chromosomal DNA via light and electron microscopy. Fluorescent light microscopy and EM studies showed that the parasite lay in the perinuclear zone of the host cell during interphase and segregated to daughter cells at mitosis. At metaphase, the parasite was frequently closely associated with host microtubules and mitochondria. Electron-dense bridges were observed between the parasites and the host microtubules and also between host mitochondria and microtubules. The study suggests that both the parasite and the host cell organelles segregate in association with spindle microtubules.
|Copyright, Publisher and Additional Information:||Copyright © 1999 Cambridge University Press.|
|Keywords:||microsporidian, mitosis, microtubule, mitochondria, Nosema sp.|
|Institution:||The University of Leeds|
|Academic Units:||The University of Leeds > Faculty of Biological Sciences (Leeds) > Institute of Integrative and Comparative Biology (Leeds)|
|Depositing User:||Repository Officer|
|Date Deposited:||14 Mar 2006|
|Last Modified:||06 Jun 2014 05:10|