Kakaawla, T.K.K., Hartley, W.C. and Harrity, J.P.A. (2016) Synthesis and Cycloaddition Reactions of Stabilized Münchnones. European Journal of Organic Chemistry, 2016 (16). pp. 2789-2792. ISSN 1434-193X
Abstract
A family of stabilized münchnones bearing an acyl group at C4 have been prepared and studied in alkyne cycloaddition reactions. These reactions are highly regioselective, and the method represents a rapid and straightforward route to densely substituted pyrroles. Finally, the C4-stabilizing units can be further manipulated to furnish carboxylic acid and amide groups, or removed altogether to provide unsubstituted pyrroles.
Metadata
| Authors/Creators: |
|
|---|---|
| Copyright, Publisher and Additional Information: | © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. |
| Keywords: | Münchnones; Cycloaddition; Pyrroles; Regioselectivity; Heterocycles |
| Dates: |
|
| Institution: | The University of Sheffield |
| Academic Units: | The University of Sheffield > Faculty of Science (Sheffield) > Department of Chemistry (Sheffield) |
| Depositing User: | Symplectic Sheffield |
| Date Deposited: | 13 Jun 2016 15:28 |
| Last Modified: | 08 Jul 2016 14:24 |
| Published Version: | http://dx.doi.org/10.1002/ejoc.201600486 |
| Status: | Published |
| Publisher: | Wiley-VCH Verlag |
| Refereed: | Yes |
| Identification Number: | https://doi.org/10.1002/ejoc.201600486 |
Download not available
A full text copy of this item is not currently available from White Rose Research Online
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)