Fazeli, A. orcid.org/0000-0003-0870-9914 and Holt, W.V. (2016) Cross talk during the periconception period. Theriogenology, 86 (1). pp. 438-442. ISSN 0093-691X
Abstract
The cross talk between gametes, embryos, and female reproductive tract plays a crucial role in fine tuning of different reproductive events as well as influencing the epigenetic profile of offspring and their health in adulthood. Here, we describe some background to the recent investigations leading to the discovery of this cross talk. We will also point to important requirements for understanding the maternal communication with gametes and embryos. Finally, we mention two probable hypotheses regarding how gametes and embryos are recognized by the female reproductive tract. It is clear that understanding this cross talk is leading to the production of new means for increasing fertility and potentials for affecting the epigenomic profile of an individual.
Metadata
Authors/Creators: |
|
||||||||||||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Copyright, Publisher and Additional Information: | © 2016 Elsevier Inc. This is an author produced version of a paper subsequently published in Theriogenology. Uploaded in accordance with the publisher's self-archiving policy. | ||||||||||||||||||||||||
Keywords: | Embryo; Fallopian tube; Oocyte; Oviduct; Periconception; Spermatozoa | ||||||||||||||||||||||||
Dates: |
|
||||||||||||||||||||||||
Institution: | The University of Sheffield | ||||||||||||||||||||||||
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > Department of Human Metabolism (Sheffield) | ||||||||||||||||||||||||
Funding Information: |
|
||||||||||||||||||||||||
Depositing User: | Symplectic Sheffield | ||||||||||||||||||||||||
Date Deposited: | 18 May 2016 08:37 | ||||||||||||||||||||||||
Last Modified: | 24 Apr 2017 00:18 | ||||||||||||||||||||||||
Published Version: | http://dx.doi.org/10.1016/j.theriogenology.2016.04... | ||||||||||||||||||||||||
Status: | Published | ||||||||||||||||||||||||
Publisher: | Elsevier | ||||||||||||||||||||||||
Refereed: | Yes | ||||||||||||||||||||||||
Identification Number: | https://doi.org/10.1016/j.theriogenology.2016.04.059 | ||||||||||||||||||||||||
Related URLs: |