Global Proteotoxicity Caused by Human β2 Microglobulin Variants Impairs the Unfolded Protein Response in C. elegans

Good, SG, Dewison, KM, Radford, SE orcid.org/0000-0002-3079-8039 et al. (1 more author) (2021) Global Proteotoxicity Caused by Human β2 Microglobulin Variants Impairs the Unfolded Protein Response in C. elegans. International Journal of Molecular Sciences, 22 (19). 10752. ISSN 1661-6596

Abstract

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Authors/Creators:
Copyright, Publisher and Additional Information: © 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
Keywords: β2 microglobulin; systemic amyloidosis; protein misfolding; C. elegans; extracellular; ER stress; UPRER; proteotoxicity; stress response
Dates:
  • Accepted: 1 October 2021
  • Published (online): 4 October 2021
  • Published: 4 October 2021
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Molecular and Cellular Biology (Leeds) > Structural Molecular Biology (Leeds)
Funding Information:
FunderGrant number
NC3RsNC/P001203/1
Depositing User: Symplectic Publications
Date Deposited: 15 Oct 2021 13:52
Last Modified: 25 Jun 2023 22:47
Status: Published
Publisher: MDPI
Identification Number: https://doi.org/10.3390/ijms221910752

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