An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK)

Al-Khawaldeh, Islam, Alyassiri, Mohammed, Aldred, Greg et al. (29 more authors) (2021) An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK). JOURNAL OF MEDICINAL CHEMISTRY. 10001–10018. ISSN 0022-2623

Metadata

Authors/Creators:
  • Al-Khawaldeh, Islam
  • Alyassiri, Mohammed
  • Aldred, Greg
  • Basmadjian, Christine
  • Bordoni, Cinzia
  • Harnor, Suzannah J.
  • Heptinstall, Amy B.
  • Hobson, Stephen
  • Jennings, Claire
  • Khalifa, Shaimaa
  • Lebraud, Honorine
  • Martin, Mathew P.
  • Miller, Duncan C
  • Shrives, Harry
  • De Souza, Joao
  • Stewart, Hannah
  • Temple, Max J
  • Thomas, Huw
  • Totobenazara, Jane
  • Tucker, Julie Ann ORCID logo https://orcid.org/0000-0002-6119-676X
  • Tudhope, Susan
  • Wang, Lan-Zhen
  • Bronowska, Agnieszka
  • Cano, Celine
  • Endicott, Jane A.
  • Golding, Bernard
  • Hardcastle, Ian R.
  • Hickson, Ian
  • Wedge, Stephen
  • Willmore, Elaine
  • Noble, Martin E. M.
  • Waring, Michael J.
Copyright, Publisher and Additional Information: © 2021 American Chemical Society. This is an author-produced version of the published paper. Uploaded in accordance with the publisher’s self-archiving policy. Further copying may not be permitted; contact the publisher for details.
Dates:
  • Submitted: 24 May 2021
  • Accepted: 24 June 2021
  • Published (online): 2 July 2021
  • Published: 22 July 2021
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Biology (York)
Depositing User: Pure (York)
Date Deposited: 28 Jun 2021 14:10
Last Modified: 06 Dec 2023 14:16
Published Version: https://doi.org/10.1021/acs.jmedchem.0c01249
Status: Published
Refereed: Yes
Identification Number: https://doi.org/10.1021/acs.jmedchem.0c01249

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