Structure of human endo-a-1,2-mannosidase (MANEA), an antiviral host-glycosylation target

Sobala, Lukasz F. orcid.org/0000-0002-3807-6452, Fernandes, Pearl Z., Hakki, Zalihe et al. (10 more authors) (2020) Structure of human endo-a-1,2-mannosidase (MANEA), an antiviral host-glycosylation target. Proceedings of the National Academy of Sciences of the United States of America. pp. 29595-29601. ISSN 1091-6490

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Copyright, Publisher and Additional Information: Funding Information: ACKNOWLEDGMENTS. We thank Jon Agirre for assistance with generating a dictionary file for TEW, Eleanor Dodson for assistance with processing the highly anisotropic datasets, Alexandra Males for collecting ITC data with Glc-DMJ, and Mahima Sharma for assisting with supplemental figure production. We also thank Diamond Light Source UK for access to beamlines I03, I04, and I24 (Proposals mx1221, mx12587, and mx18598). Support for this work was provided by the European Research Council (ERC-2012-AdG-32294, “Glycopoise”), the Australian Research Council (DP120101396, FT130100103, and DP180101957), and the Royal Society (a Ken Murray Research Professorship, to G.J.D.). Publisher Copyright: © 2020 National Academy of Sciences. All rights reserved. Copyright: Copyright 2020 Elsevier B.V., All rights reserved.
Keywords: Antiviral, Enzyme, Glycosylation, Secretory pathway, Structural biology
Dates:
  • Accepted: 28 September 2020
  • Published (online): 5 November 2020
  • Published: 24 November 2020
Institution: The University of York
Academic Units: The University of York > Faculty of Sciences (York) > Chemistry (York)
Depositing User: Pure (York)
Date Deposited: 23 Feb 2021 17:20
Last Modified: 04 Feb 2024 01:10
Published Version: https://doi.org/10.1073/pnas.2013620117
Status: Published
Refereed: Yes
Identification Number: https://doi.org/10.1073/pnas.2013620117
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