Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site

Wright, DJ, Simmons, KJ, Johnson, RM et al. (3 more authors) (2020) Human TRPC5 structures reveal interaction of a xanthine-based TRPC1/4/5 inhibitor with a conserved lipid binding site. Communications Biology, 3 (1). 704. ISSN 2399-3642

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Copyright, Publisher and Additional Information: © The Author(s) 2020. This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/ licenses/by/4.0/.
Dates:
  • Published: 23 November 2020
  • Accepted: 23 October 2020
  • Published (online): 23 November 2020
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Leeds Institute of Cardiovascular and Metabolic Medicine (LICAMM) > Discovery & Translational Science Dept (Leeds)
Funding Information:
FunderGrant number
BBSRC (Biotechnology & Biological Sciences Research Council)BB/P020208/1
Depositing User: Symplectic Publications
Date Deposited: 01 Dec 2020 14:59
Last Modified: 01 Dec 2020 14:59
Status: Published
Publisher: Nature Research
Identification Number: https://doi.org/10.1038/s42003-020-01437-8

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