Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases

Omar, F., Findlay, J.E., Carfray, G. et al. (19 more authors) (2019) Small-molecule allosteric activators of PDE4 long form cyclic AMP phosphodiesterases. Proceedings of the National Academy of Sciences, 116 (27). pp. 13320-13329. ISSN 0027-8424

Abstract

Metadata

Authors/Creators:
  • Omar, F.
  • Findlay, J.E.
  • Carfray, G.
  • Allcock, R.W.
  • Jiang, Z.
  • Moore, C.
  • Muir, A.L.
  • Lannoy, M.
  • Fertig, B.A.
  • Mai, D.
  • Day, J.P.
  • Bolger, G.
  • Baillie, G.S.
  • Schwiebert, E.
  • Klussmann, E.
  • Pyne, N.J.
  • Ong, A.C.M. ORCID logo https://orcid.org/0000-0002-7211-5400
  • Bowers, K.
  • Adam, J.M.
  • Adams, D.R.
  • Houslay, M.D.
  • Henderson, D.J.P.
Copyright, Publisher and Additional Information: © 2019 the Author(s). Published by PNAS. This open access article is distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: ADPKD; PDE4; PDE4 activator; cyclic AMP; phosphodiesterase
Dates:
  • Accepted: 23 May 2019
  • Published (online): 17 June 2019
  • Published: 2 July 2019
Institution: The University of Sheffield
Academic Units: The University of Sheffield > Sheffield Teaching Hospitals
Depositing User: Symplectic Sheffield
Date Deposited: 09 Jul 2019 10:15
Last Modified: 09 Jul 2019 10:15
Status: Published
Publisher: National Academy of Sciences
Refereed: Yes
Identification Number: https://doi.org/10.1073/pnas.1822113116
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