Sengupta, R, Marzo-Ortega, H, McGonagle, D et al. (2 more authors) (2018) Short-term Repeat Magnetic Resonance Imaging Scans in Suspected Early Axial Spondyloarthritis Are Clinically Relevant Only in HLA-B27–positive Male Subjects. The Journal of Rheumatology, 45 (2). pp. 202-205. ISSN 0315-162X
Abstract
Objective; Our study investigated the natural history of magnetic resonance imaging (MRI)–determined bone marrow edema over a 12-week period in individuals with suspected axial spondyloarthritis.
Methods; There were 109 MRI scans performed on 30 patients who fulfilled the Assessment of Spondyloarthritis international Society inflammatory back pain criteria at baseline and at 4, 8, and 12 weeks.
Results; There were 29 patients who completed the study. Only 4 (14%) patients changed from MRI-negative to MRI-positive (all HLA-B27–positive, OR 2.74). Three of 7 (43%) male HLA-B27–positive patients, 1 of 8 (12.5%) HLA-B27–positive female patients, and no HLA-B27–negative patients changed from MRI- negative to -positive.
Conclusion; Repeat MRI scans within a 12-week period should be considered in HLA-B27–positive males.
Metadata
| Authors/Creators: |
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| Keywords: | MAGNETIC RESONANCE IMAGING; DIAGNOSIS; AXIAL SPONDYLOARTHRITIS |
| Dates: |
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| Institution: | The University of Leeds |
| Academic Units: | The University of Leeds > Faculty of Medicine and Health (Leeds) > School of Medicine (Leeds) > Institute of Rheumatology & Musculoskeletal Medicine (LIRMM) (Leeds) > Experimental Musculoskeletal Medicine (Leeds) |
| Depositing User: | Symplectic Publications |
| Date Deposited: | 23 Oct 2018 14:23 |
| Last Modified: | 14 Feb 2019 13:51 |
| Status: | Published |
| Publisher: | Journal of Rheumatology |
| Identification Number: | https://doi.org/10.3899/jrheum.170171 |
CORE (COnnecting REpositories)
CORE (COnnecting REpositories)