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p+ p+ p+ p+ p+ + + + 8 + t 0, + 5 X \5 \5 \5 \5 K6 v 6 $ 6 $ 0 V p+ 6 K6 K6 6 6 p+ p+ \5 \5 ж ? ? ? 6 N p+ \5 p+ \5 ? 6 ? ? ^ 4 \5 Ќfz G8 ^ h 0 } ( 8 8 8 8 p+ @ 6 6 ? 6 6 6 6 6 ? 6 6 6 6 6 6 6 8 6 6 6 6 6 6 6 6 6 6* : Table 1:
Table 1 Legend: Summary of studies included in the meta-analysis (n = 13 data sets representing 14 identified records).
StudyNumber of participantsAge rangeParameters of interest measuredAdiposity classifications of interest data available for
Alvarez et al. (2006) 38812-19 yearsTC, TG, HDL-c, LDL-c, glucose, insulin.BMI, UW/NW, OW/Ob (females only)Burke et al. (2004) ADDIN EN.CITE Burke200410712(27)107121071217Burke, V.Beilin, L.Dunbar, D.Kevan, M.Associations between blood pressure and overweight defined by new standards for body mass index in childhoodPreventive MedicinePreventive Medicine558-56438520040091743510.1016/j.ypmed.2003.09.023 1,31012 yearsSBP, DBP.BMI, UW/NW, OW/Ob (separated by sex)Chiolero et al. (2006) 7,80411-18 yearsSBP, DBP.BMI. All classifications for both sexes (raw data provided)Cobayashi et al. 2010) ADDIN EN.CITE Cobayashi2010486(29)48648617Cobayashi, F.Oliveira, F. L.Escrivao, M. A.Daniela, S.Taddei, J. A.Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil.Obesity and cardiovascular risk factors in adolescents attending public schoolsArquivos Brasileiros de CardiologiaArquivos brasileiros de cardiologia200-59522010/07/06AdolescentBlood Pressure/ physiologyBody Mass IndexCardiovascular Diseases/ prevention & controlCase-Control StudiesFemaleHealth PromotionHumansHypertension/prevention & controlMaleNational Health ProgramsObesity/ prevention & controlPublic SectorRisk FactorsSchoolsYoung Adult2010Aug1678-4170 (Electronic)
0066-782X (Linking)20602009NLMeng
por 32114-19 yearsSBP, DBP, TC, TG, HDL-c, LDL-c, insulin.BMI. All classifications for both sexes (raw data provided)Duncan et al. (2011) 62211-14 yearsSBP, DBP.BMI. All classifications for both sexes (raw data provided)Jung et al. (2010) ADDIN EN.CITE Jung20108553(31)8553855317Jung, ChristianGerdes, NorbertFritzenwanger, MichaelFigulla, Hans ReinerCirculating levels of interleukin-1 family cytokines in overweight adolescentsMediators of InflammationMediators of InflammationArticle ID 958403201020100962-9351BCI:BCI201000198225<Go to ISI>://BCI:BCI201000198225http://downloads.hindawi.com/journals/mi/2010/958403.pdf10.1155/2010/958403 (also represents Jung et al. (2009))7713-17 yearsTC, TG, HDL-c, LDL-c.BMI, WC, WHtR. All classifications, males only (raw data provided)Klein-Platat et al. (2005) 12012 yearsSBP, DBP, TG, HDL-c, glucose, insulin. BMI, UW/NW, OW/Ob (sexes combined)Kollias et al. (2009)
55812-17 yearsSBP, DBP.BMI. All classifications for both sexes (raw data provided)Lurbe et al. (2006)
46511-18 yearsSBP, DBP.BMI, UW/NW, OW (sexes combined)Manios et al. (2005) 51012-13 yearsTC, TG, HDL-c, LDL-c.BMI, NW, OW/Ob (separated by sex)Martinez-Gomez et al. (2010) 42513-18.5 yearsTC, TG, HDL-c, LDL-c, glucose.BMI, UW/NW, OW/Ob (sexes combined)Musso et al. (2011)
96611-19 yearsSBP, DBP, TC, TG, HDL-c, LDL-c, glucose, insulin.BMI, WC, WHtR. All classifications for both sexes (raw data provided)Sur et al. (2005)
1,04412-13 yearsTC, TG, HDL-c, LDL-c.BMI, UW/NW, OW/Ob (separated by sex)N.B. Manios et al. 2005 and Sur et al. 2005 include data from the same population. However, as the method for subdividing the data within each study was different these two studies were never included in the same analysis and so both studies were retained. BMI = Body mass index; WC = Waist circumference; WHtR = Waist to height ratio; SBP = Systolic blood pressure; DBP = Diastolic blood pressure; TC = Total cholesterol; TG = Triglycerides; HDL-c = High density lipoprotein cholesterol; LDL-c = Low density lipoprotein cholesterol.
Table 2:
Table 3 Legend: Quality assessment of studies included in the meta-analysis (n = 13).
StudyQuality assessment item (low, medium or high risk)Overall assessment (High, medium or low risk)Study sample selectionOutcome assessmentAttrition BiasReporting BiasSuitability of methodsAlvarez et al. 2006LOWHIGHLOWLOWLOWHIGHBurke et al. 2004LOWMEDIUMLOWLOWLOWMEDIUMChiolero et al. 2006LOWMEDIUMLOWLOWLOWMEDIUMCobayashi et al. 2010MEDIUMMEDIUMLOWLOWMEDIUMMEDIUMDuncan et al. 2011MEDIUMMEDIUMLOWLOWLOWMEDIUMJung et al. 2010MEDIUMMEDIUMLOWLOWMEDIUMMEDIUMKlein Platat et al. 2005MEDIUMMEDIUMLOWLOWLOWMEDIUMKollias et al. 2009MEDIUMMEDIUMLOWLOWLOWMEDIUMLurbe et al. 2006MEDIUMMEDIUMLOWLOW MEDIUMMEDIUMManios et al. 2005MEDIUMHIGHLOWLOWLOWHIGHMartinez-Gomez et al. 2010HIGHHIGHLOWLOWLOWHIGHMusso et al. 2011MEDIUMMEDIUMLOWLOWMEDIUMMEDIUMSur et al. 2005MEDIUMHIGHLOWLOWLOWHIGHSupplementary Table 1: Mean differences in triglyceride levels between normal weight and overweight/obese groups when waist circumference was used as an adiposity index.
No studies
(No participants)
Mean difference, mmolL-1 (95% CI)Heterogeneity,
I2Test for overall effectAll2 (1,027)-0.16
(-0.28 to -0.04)68%Z = 2.60
P = 0.009Males2 (597)-0.22
(-0.30 to -0.14)0%Z = 5.41
P < 0.00001Females
1 (430)-0.07
( - 0 . 1 6 t o 0 . 0 2 ) n / a Z = 1 . 5 4
P = 0 . 1 2
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