Pedrazzoli, D., Boccia, D., Dodd, P.J. orcid.org/0000-0001-5825-9347 et al. (6 more authors) (2017) Modelling the social and structural determinants of tuberculosis: opportunities and challenges. International Journal of Tuberculosis and Lung Disease, 21 (9). pp. 957-964. ISSN 1027-3719
Abstract
INTRODUCTION: Despite the close link between tuberculosis (TB) and poverty, most mathematical models of TB have not addressed underlying social and structural determinants.
OBJECTIVE: To review studies employing mathematical modelling to evaluate the epidemiological impact of the structural determinants of TB.
METHODS: We systematically searched PubMed and personal libraries to identify eligible articles. We extracted data on the modelling techniques employed, research question, types of structural determinants modelled and setting.
RESULTS: From 232 records identified, we included eight articles published between 2008 and 2015; six employed population-based dynamic TB transmission models and two non-dynamic analytic models. Seven studies focused on proximal TB determinants (four on nutritional status, one on wealth, one on indoor air pollution, and one examined overcrowding, socio-economic and nutritional status), and one focused on macro-economic influences.
CONCLUSIONS: Few modelling studies have attempted to evaluate structural determinants of TB, resulting in key knowledge gaps. Despite the challenges of modelling such a complex system, models must broaden their scope to remain useful for policy making. Given the intersectoral nature of the interrelations between structural determinants and TB outcomes, this work will require multidisciplinary collaborations. A useful starting point would be to focus on developing relatively simple models that can strengthen our knowledge regarding the potential effect of the structural determinants on TB outcomes.
Metadata
Authors/Creators: |
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Copyright, Publisher and Additional Information: | © 2017 Pedrazzoli et al. This is an author-produced version of a paper accepted for publication in International Journal of Tuberculosis and Lung Disease. Uploaded in accordance with the publisher's self-archiving policy. |
Keywords: | mathematical modelling; tuberculosis; social determinants |
Dates: |
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Institution: | The University of Sheffield |
Academic Units: | The University of Sheffield > Faculty of Medicine, Dentistry and Health (Sheffield) > School of Health and Related Research (Sheffield) > ScHARR - Sheffield Centre for Health and Related Research |
Depositing User: | Symplectic Sheffield |
Date Deposited: | 26 Sep 2017 13:49 |
Last Modified: | 01 Mar 2018 01:39 |
Published Version: | https://doi.org/10.5588/ijtld.16.0906 |
Status: | Published |
Publisher: | International Union Against Tuberculosis and Lung Disease |
Refereed: | Yes |
Identification Number: | https://doi.org/10.5588/ijtld.16.0906 |
Related URLs: |