Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

Boeynaems, S, Bogaert, E, Kovacs, D et al. (24 more authors) (2017) Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics. Molecular Cell, 65 (6). 1044-1055.e5. ISSN 1097-2765

Abstract

Metadata

Authors/Creators:
  • Boeynaems, S
  • Bogaert, E
  • Kovacs, D
  • Konijnenberg, A
  • Timmerman, E
  • Volkov, A
  • Guharoy, M
  • Decker, MD
  • Jaspers, T
  • Ryan, VH
  • Janke, AM
  • Baatsen, P
  • Vercruysse, T
  • Kolaitis, R-M
  • Daelemans, D
  • Taylor, JP
  • Kedersha, N
  • Anderson, P
  • Impens, F
  • Sobott, F
  • Schymkowitz, J
  • Rousseau, F
  • Fawzi, NL
  • Robberecht, W
  • Van Damme, P
  • Tompa, P
  • Van Den Bosch, L
Copyright, Publisher and Additional Information: © 2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
Keywords: amyotrophic lateral sclerosis; frontotemporal lobar degeneration; phase transition; protein aggregation; FUS; hnRNP; prion-like domain; low complexity domain; intrinsically disordered protein; LLPS
Dates:
  • Published: 16 March 2017
  • Accepted: 14 February 2017
Institution: The University of Leeds
Academic Units: The University of Leeds > Faculty of Biological Sciences (Leeds) > School of Biomedical Sciences (Leeds)
Depositing User: Symplectic Publications
Date Deposited: 21 Mar 2017 16:35
Last Modified: 05 Oct 2017 16:19
Published Version: https://doi.org/10.1016/j.molcel.2017.02.013
Status: Published
Publisher: Elsevier (Cell Press)
Identification Number: https://doi.org/10.1016/j.molcel.2017.02.013

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