Items where authors include "Wittmann, M"

Article

Carter, LM orcid.org/0000-0002-8724-5937, Alase, A, Wigston, Z et al. (10 more authors) (2023) Gene expression and autoantibody analysis reveals distinct ancestry-specific profiles associated with response to rituximab in refractory systemic lupus erythematosus. Arthritis & Rheumatology, 75 (5). pp. 697-710. ISSN 2326-5191

Macleod, T, Bridgewood, C, Hyde, I et al. (4 more authors) (2022) Molecular and cellular regulation of psoriatic inflammation. Clinical Science, 136 (12). pp. 935-952. ISSN 0143-5221

Carter, LM, Alase, A, Wigston, Z et al. (8 more authors) (2022) OA09 Gene expression analysis reveals distinct ancestry-specific profiles associated with response to rituximab in SLE. Rheumatology, 61 (Supplement_1). i4-i5. ISSN 1462-0324

Carter, LM orcid.org/0000-0002-8724-5937, McGonagle, D, Vital, EM orcid.org/0000-0003-1637-4755 et al. (1 more author) (2022) Applying Early Intervention Strategies to Autoimmune Skin Diseases. Is the Window of Opportunity Preclinical? A Dermato-Rheumatology Perspective. Journal of Investigative Dermatology, 142 (3). pp. 944-950. ISSN 0022-202X

Macleod, T, Berekmeri, A, Bridgewood, C et al. (3 more authors) (2021) The immunological impact of IL-1 family cytokines on the epidermal barrier. Frontiers in Immunology, 12. 808012. ISSN 1664-3224

Bridgewood, C, Newton, D orcid.org/0000-0002-0214-1486, Bragazzi, N orcid.org/0000-0001-8409-868X et al. (2 more authors) (2021) Unexpected connections of the IL-23/IL-17 and IL-4/IL-13 cytokine axes in inflammatory arthritis and enthesitis. Seminars in Immunology, 58. 101520. ISSN 1044-5323

Psarras, A, Antanaviciute, A, Alase, A et al. (5 more authors) (2021) TNF-α Regulates Human Plasmacytoid Dendritic Cells by Suppressing IFN-α Production and Enhancing T Cell Activation. The Journal of Immunology. ji1901358. ISSN 0022-1767

Macleod, T, Ainscough, JS, Hesse, C et al. (9 more authors) (2020) The proinflammatory cytokine IL-36γ is a global discriminator of harmless microbes and invasive pathogens within epithelial tissues. Cell Reports, 33 (11). 108515. ISSN 2211-1247

Psarras, A, Alase, A, Antanaviciute, A et al. (6 more authors) (2020) Functionally impaired plasmacytoid dendritic cells and non-haematopoietic sources of type I interferon characterize human autoimmunity. Nature Communications, 11. 6149. ISSN 2041-1723

Watad, A, Rowe, H, Russell, T et al. (18 more authors) (2020) Normal human enthesis harbours conventional CD4+ and CD8+ T cells with regulatory features and inducible IL-17A and TNF expression. Annals of the Rheumatic Diseases, 79 (8). pp. 1044-1054. ISSN 0003-4967

De Marco, G orcid.org/0000-0003-2406-161X, Berekméri, A, Coates, LC et al. (12 more authors) (2020) Systematic literature review of non-topical treatments for early, untreated (systemic therapy naïve) psoriatic disease: a GRAPPA initiative. Rheumatology Advances in Practice. ISSN 2514-1775

El-Sherbiny, YM orcid.org/0000-0003-4791-3475, Md Yusof, MY orcid.org/0000-0003-3131-9121, Psarras, A et al. (11 more authors) (2020) B Cell Tetherin: A Flow Cytometric Cell‐Specific Assay for Response to Type I Interferon Predicts Clinical Features and Flares in Systemic Lupus Erythematosus. Arthritis & Rheumatology, 72 (5). pp. 769-779. ISSN 2326-5191

Bridgewood, C, Russell, T, Weedon, H et al. (7 more authors) (2019) The novel cytokine Metrnl/IL-41 is elevated in Psoriatic Arthritis synovium and inducible from both entheseal and synovial fibroblasts. Clinical Immunology, 208. 108253. ISSN 1521-6616

Md Yusof, MY orcid.org/0000-0003-3131-9121, Britton, J, Edward, S et al. (6 more authors) (2019) Validity and sensitivity to change of laser Doppler imaging as a novel objective outcome measure for cutaneous lupus erythematosus. Lupus, 28 (11). pp. 1320-1328. ISSN 0961-2033

Berekmeri, A, Tiganescu, A orcid.org/0000-0003-3688-2204, Alase, AA et al. (3 more authors) (2019) Non-invasive Approaches for the Diagnosis of Autoimmune/Autoinflammatory Skin Diseases—A Focus on Psoriasis and Lupus erythematosus. Frontiers in Immunology, 10. 1931. ISSN 1664-3224

Shalbaf, M, Alase, AA, Berekmeri, A et al. (8 more authors) (2019) Plucked hair follicles from patients with chronic discoid lupus erythematosus show a disease-specific molecular signature. Lupus Science and Medicine, 6 (1). e000328. ISSN 2053-8790

Bridgewood, C, Watad, A, Russell, T et al. (10 more authors) (2019) Identification of myeloid cells in the human enthesis as the main source of local IL-23 production. Annals of the rheumatic diseases, 78 (7). pp. 929-933. ISSN 0003-4967

Bridgewood, C, Alase, A, Watad, A et al. (3 more authors) (2019) Correction to: The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 68 (6). p. 427. ISSN 1023-3830

Bridgewood, C orcid.org/0000-0002-3083-3076, Alase, A, Watad, A et al. (3 more authors) (2019) The IL-23p19/EBI3 heterodimeric cytokine termed IL-39 remains a theoretical cytokine in man. Inflammation Research, 68 (6). pp. 423-426. ISSN 1023-3830

Macleod, T, Ward, J orcid.org/0000-0001-9867-393X, Alase, AA et al. (3 more authors) (2019) Antimicrobial peptide LL-37 facilitates intracellular uptake of RNA aptamer Apt 21-2 without inducing an inflammatory or interferon response. Frontiers in Immunology, 10. 857. ISSN 1664-3224

Savage, L, Goodfield, M, Horton, L et al. (6 more authors) (2019) Regression of peripheral subclinical enthesopathy in therapy-naïve patients treated with Ustekinumab for moderate-to-severe chronic plaque psoriasis: A Fifty‐Two–Week, Prospective, Open‐Label Feasibility Study. Arthritis and Rheumatology, 71 (4). pp. 626-631. ISSN 2326-5191

Howell, SJ, Hoeks, SE, West, RM orcid.org/0000-0001-7305-3654 et al. (96 more authors) (2019) Prospective observational cohort study of the association between antiplatelet therapy, bleeding and thrombosis in patients with coronary stents undergoing noncardiac surgery. British Journal of Anaesthesia, 122 (2). pp. 170-179. ISSN 0007-0912

El-Sherbiny, YM orcid.org/0000-0003-4791-3475, Psarras, A, Yusof, MYM et al. (8 more authors) (2018) Publisher Correction: A novel two-score system for interferon status segregates autoimmune diseases and correlates with clinical features. Scientific Reports, 8. ARTN 14846. ISSN 2045-2322

Md Yusof, MY orcid.org/0000-0003-3131-9121, Psarras, A, El-Sherbiny, YM orcid.org/0000-0003-4791-3475 et al. (9 more authors) (2018) Prediction of autoimmune connective tissue disease in an at-risk cohort: prognostic value of a novel two-score system for interferon status. Annals of the Rheumatic Diseases, 77 (10). pp. 1432-1439. ISSN 0003-4967

Berekméri, A, Latzko, A, Alase, A et al. (12 more authors) (2018) Detection of IL-36γ through noninvasive tape stripping reliably discriminates psoriasis from atopic eczema. Journal of Allergy and Clinical Immunology, 142 (3). 988-991.e4. ISSN 0091-6749

Berekmeri, A, Mahmood, F, Wittmann, M orcid.org/0000-0003-2328-4926 et al. (1 more author) (2018) Tofacitinib for the treatment of psoriasis and psoriatic arthritis. Expert review of clinical immunology, 14 (9). pp. 719-730. ISSN 1744-666X

El-Sherbiny, YM orcid.org/0000-0003-4791-3475, Psarras, A, Md Yusof, M et al. (8 more authors) (2018) A novel two-score system for interferon status segregates autoimmune diseases and correlates with clinical features. Scientific Reports, 8. 5793. ISSN 2045-2322

Bridgewood, C, Fearnley, GW, Berekmeri, A et al. (6 more authors) (2018) IL-36 gamma Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis. Frontiers in Immunology, 9. ARTN 200. ISSN 1664-3224

Harrison, SR, Scambler, T, Oubussad, L et al. (4 more authors) (2018) Inositol-Requiring Enzyme 1-Mediated Downregulation of MicroRNA (miR)-146a and miR-155 in Primary Dermal Fibroblasts across Three TNFRSF1A Mutations Results in Hyperresponsiveness to Lipopolysaccharide. Frontiers in Immunology, 9. 173. ISSN 1664-3224

Bridgewood, C, Stacey, M orcid.org/0000-0003-3502-5542, Alase, A et al. (3 more authors) (2017) IL-36γ has proinflammatory effects on human endothelial cells. Experimental Dermatology, 26 (5). pp. 402-408. ISSN 0906-6705

Ainscough, JS, Macleod, T, McGonagle, D et al. (5 more authors) (2017) Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36γ. Proceedings of the National Academy of Sciences, 114 (13). E2748-E2757. ISSN 0027-8424

Smith, IL, Brown, S orcid.org/0000-0002-1840-3786, Nixon, J orcid.org/0000-0003-1705-7698 et al. (11 more authors) (2017) Treatment of severe, chronic hand eczema. Results from a UK-wide survey. Clinical and Experimental Dermatology, 42 (2). pp. 185-188. ISSN 0307-6938

Macleod, T, Doble, R, McGonagle, D et al. (4 more authors) (2016) Neutrophil Elastase-mediated proteolysis activates the antiinflammatory cytokine IL-36 Receptor antagonist. Scientific Reports. 24880. ISSN 2045-2322

Alase, AA, El-Sherbiny, Y orcid.org/0000-0003-4791-3475, Vital, EM orcid.org/0000-0003-1637-4755 et al. (3 more authors) (2015) IFNλ Stimulates MxA Production in Human Dermal Fibroblasts via a MAPK-Dependent STAT1-Independent Mechanism. Journal of Investigative Dermatology, 135 (12). pp. 2935-2943. ISSN 0022-202X

Richards, KH, Wasson, CW, Watherston, O et al. (4 more authors) (2015) The human papillomavirus (HPV) E7 protein antagonises an Imiquimod-induced inflammatory pathway in primary human keratinocytes. Scientific Reports, 5. 12922. ISSN 2045-2322

Seltmann, J, Roesner, LM, von Hesler, F-W et al. (2 more authors) (2015) IL-33 impacts on the skin barrier by downregulating the expression of filaggrin. Journal of Allergy and Clinical Immunology, 135 (6). 1659-1661.e4. ISSN 0091-6749

Vital, EM orcid.org/0000-0003-1637-4755, Wittmann, M orcid.org/0000-0003-2328-4926, Edward, S et al. (5 more authors) (2015) Brief report: Responses to rituximab suggest B cell-independent inflammation in cutaneous systemic lupus erythematosus. Arthritis and Rheumatology, 67 (6). pp. 1586-1591. ISSN 2326-5191

D'Erme, AM, Wilsmann-Theis, D, Wagenpfeil, J et al. (8 more authors) (2015) IL-36γ (IL-1F9) Is a Biomarker for Psoriasis Skin Lesions. Journal of Investigative Dermatology, 135 (4). 1025 - 1032. ISSN 0022-202X

Richards, KH, Doble, R, Wasson, CW et al. (4 more authors) (2014) Human Papillomavirus E7 oncoprotein increases production of the anti-inflammatory IL-18 binding protein (IL-18BP) in keratinocytes. Journal of Virology, 88 (8). 4173 - 4179. ISSN 0022-538X

Doble, R, McDermott, MF, Cesur, O et al. (2 more authors) (2014) IL-17A RNA aptamer: possible therapeutic potential in some cells, more than we bargained for in others? Journal of Investigative Dermatology, 134 (3). 852 - 855. ISSN 0022-202X

Aydin, SZ, Castillo-Gallego, C, Ash, ZR et al. (5 more authors) (2013) Potential Use of Optical Coherence Tomography and High-Frequency Ultrasound for the Assessment of Nail Disease in Psoriasis and Psoriatic Arthritis. Dermatology, 227 (1). pp. 45-51. ISSN 1018-8665

Wittmann, M and Helliwell, PS (2013) Phosphodiesterase 4 inhibition in the treatment of psoriasis, psoriatic arthritis and other chronic inflammatory diseases. Dermatology and Therapy, 3 (1). 1 - 15. ISSN 2193-8210

Wittmann, M, Doble, R, Bachmann, M et al. (3 more authors) (2012) IL-27 regulates IL-18 binding protein in skin resident cells. PLoS One, 7 (6). ARTN e38751. ISSN 1932-6203

Conference or Workshop Item

Rowe, H, Watad, A, Russell, T et al. (13 more authors) (2020) SAT0361 HEALTHY HUMAN SPINAL PROCESSES PERI-ENTHESEAL T-CELLS EXHIBIT A TR1 RATHER THAN A FOXP3 REGULATORY PHENOTYPE. In: EULAR 2020, 03-06 Jun 2020, Online.

Rowe, H, Watad, A, Bridgewood, C et al. (9 more authors) (2019) In Vitro Human Enthesitis Model with Induced IL-17A and TNF alpha from CD4+and CD8+T Cells and Effect of Pharmacological Antagonism with Janus Kinase and Retinoic Acid Receptor-related Orphan Receptor gamma Inhibition. In: 2019 ACR/ARP Annual Meeting, 08-13 Nov 2019, Atlanta, GA, USA.

Proceedings Paper

De Marco, G, Berekméri, A, Coates, LC et al. (10 more authors) (2019) Non Topical Pharmacological Treatment of Early, Untreated (DMARD-Naive, Systematic Therapy-Naive) Psoriatic Disease: a Systematic Review. In: Annals of the Rheumatic Diseases. EULAR 2019: Annual European Congress of Rheumatology, 12-15 Jun 2019, Madrid, Spain. BMJ Publishing Group , p. 904.

Md Yusof, MY orcid.org/0000-0003-3131-9121, Britton, J, Hensor, EM orcid.org/0000-0002-5245-4755 et al. (4 more authors) (2017) Laser doppler imaging: an objective outcome measure for assessment of cutaneous lupus erythematosus. In: Annals of the Rheumatic Diseases. Annual European Congress of Rheumatology (EULAR 2017), 14-17 Jun 2017, Madrid, Spain. BMJ Publishing Group , pp. 1019-1020.

Md Yusof, MY orcid.org/0000-0003-3131-9121, El-Sherbiny, Y orcid.org/0000-0003-4791-3475, Psarras, A et al. (6 more authors) (2017) Prediction of connective tissue disease in an at-risk cohort using a novel interferon stimulated gene expression score. In: Annals of the Rheumatic Diseases. Annual European Congress of Rheumatology (EULAR 2017), 14-17 Jun 2017, Madrid, Spain. BMJ Publishing Group , p. 91.

Tiganescu, A orcid.org/0000-0003-3688-2204, Farraj, LA, Carr, IM orcid.org/0000-0001-9544-1068 et al. (6 more authors) (2016) 11 beta-hydroxysteroid dehydrogenase type 1 mediates anti-inflammatory, pro-inflammatory and inflammation-independent effects in primary human dermal fibroblasts. In: British Journal of Dermatology. British Skin Foundation, Skin Deep - 20 Years of Research, 20th Anniversary Conference, 13 Oct 2016, London, United Kingdom. Wiley , p. 64.

Wittmann, M orcid.org/0000-0003-2328-4926, Macleod, T, Ainscough, JS et al. (5 more authors) (2016) Activation of IL-36 molecules and their role in psoriatic disease. In: British Journal of Dermatology. 20th Anniversary Conference of the British Skin Foundation, Skin Deep - 20 Years of Research, 13 Oct 2016, London, UK. Wiley , p. 68.

Macleod, T, Doble, R, Wittmann, M orcid.org/0000-0003-2328-4926 et al. (2 more authors) (2016) Neutrophil mediated proteolysis of IL-36 members has both regulatory and inflammatory consequences. In: Journal of Investigative Dermatology. European Society for Dermatological Research (ESDR) Annual Meeting, 07-10 Sep 2016, Munich, Germany. Elsevier , S230-S230.

Bridgewood, C, Stacey, M orcid.org/0000-0003-3502-5542, Alase, A et al. (3 more authors) (2016) IL-36y stimulation induces proinflammatory effects on human endothelial cells. In: Journal of Investigative Dermatology. European Society for Dermatological Research (ESDR) Annual Meeting, 07-10 Sep 2016, Munich, Germany. Elsevier , S216-S216.

Keszegpál, A, Latzko, A, Macleod, T et al. (4 more authors) (2016) Identification of the skin psoriatic inflammation profile by cytokine analysis from tape stripping. In: Journal of Investigative Dermatology. European Society for Dermatological Research (ESDR) Annual Meeting, 07-10 Sep 2016, Munich, Germany. Elsevier , S233-S233.

Alase, A, Stacey, M orcid.org/0000-0003-3502-5542, Goodfield, M et al. (1 more author) (2016) The production and responsiveness to skin interferon (IFNλ1) are regulated by TNF-α. In: Journal of Investigative Dermatology. European Society for Dermatological Research (ESDR) Annual Meeting, 07-10 Sep 2016, Munich, Germany. Elsevier , S230-S230.

El-Sherbiny, Y orcid.org/0000-0003-4791-3475, Md Yusof, MY orcid.org/0000-0003-3131-9121, Hensor, E orcid.org/0000-0002-5245-4755 et al. (3 more authors) (2016) Surface Tetherin Is A Novel Cell-Specific Biomarker for Interferon Response in Systemic Lupus Erythematosus. In: Annals of the Rheumatic Diseases. Annual European Congress of Rheumatology: EULAR 2016, 08-11 Jun 2016, London, UK. BMJ Publishing Group , p. 546.

Md Yusof, MY orcid.org/0000-0003-3131-9121, El-Sherbiny, Y orcid.org/0000-0003-4791-3475, Psarras, A et al. (4 more authors) (2016) Incomplete and Systemic Lupus Erythematosus Reveal A Different Pattern of Interferon-Stimulated Genes Up-Regulation. In: Annals of the Rheumatic Diseases. Annual European Congress of Rheumatology (EULAR 2016), 08-11 Jun 2016, London, UK. BMJ Publishing Group , pp. 285-286.