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Article

Felix-Ilemhenbhio, F., Pickering, G.A.E., Kiss-Toth, E. orcid.org/0000-0003-4406-4017 et al. (1 more author) (2022) Pathophysiology and emerging molecular therapeutic targets in heterotopic ossification. International Journal of Molecular Sciences, 23 (13). 6983. ISSN 1422-0067

Kreitmaier, P., Suderman, M., Southam, L. et al. (7 more authors) (2022) An epigenome-wide view of osteoarthritis in primary tissues. The American Journal of Human Genetics. ISSN 0002-9297

Miller, L.L., Prieto-Alhambra, D., Trela-Larsen, L. et al. (4 more authors) (2022) Revision and 90-day mortality following hip arthroplasty in patients with inflammatory arthritis and ankylosing spondylitis enrolled in the National Joint Registry for England and Wales. HIP International, 32 (3). pp. 371-378. ISSN 1120-7000

Deere, K., Matharu, G.S., Ben-Shlomo, Y. et al. (4 more authors) (2022) The risk of all-cause mortality, heart outcomes, cancer, and neurodegenerative disorders with cobalt-chrome-containing total hip arthroplasty implants : an analysis of the National Joint Registry. The Bone & Joint Journal, 104-B (3). pp. 359-367. ISSN 2049-4394

Katsoula, G., Steinberg, J., Tuerlings, M. et al. (6 more authors) (2022) A molecular map of long non-coding RNA expression, isoform switching and alternative splicing in osteoarthritis. Human Molecular Genetics. ISSN 0964-6906

Deere, K., Matharu, G.S., Ben-Shlomo, Y. et al. (4 more authors) (2022) The risk of all-cause mortality, heart outcomes, cancer, and neurodegenerative disorders with cobalt-chrome-containing total hip arthroplasty implants : an analysis of the National Joint Registry. The Bone & Joint Journal. -9. ISSN 2049-4394

Hawker, R.E., Miltenberger, A.K., Johnson, J.S. orcid.org/0000-0002-4587-6722 et al. (6 more authors) (2021) Model emulation to understand the joint effects of ice-nucleating particles and secondary ice production on deep convective anvil cirrus. Atmospheric Chemistry and Physics, 21 (23). pp. 17315-17343. ISSN 1680-7316

Prats-Uribe, A., Kolovos, S., Berencsi, K. et al. (15 more authors) (2021) Unicompartmental compared with total knee replacement for patients with multimorbidities : a cohort study using propensity score stratification and inverse probability weighting. Health Technology Assessment, 25 (66). pp. 1-125. ISSN 1366-5278

de Mello, F.L., Wilkinson, J.M. orcid.org/0000-0001-5577-3674 and Kadirkamanathan, V. orcid.org/0000-0002-4243-2501 (2021) Metaparametric neural networks for survival analysis. IEEE Transactions on Neural Networks and Learning Systems. ISSN 2162-237X

Bohm, E.R., Kirby, S., Trepman, E. et al. (12 more authors) (2021) Collection and reporting of patient-reported outcome measures in arthroplasty registries : multinational survey and recommendations. Clinical Orthopaedics and Related Research, 479 (10). ISSN 0009-921X

Kehayova, Y.S., Watson, E., Wilkinson, J.M. et al. (2 more authors) (2021) Genetic and epigenetic interplay within a COLGALT2 enhancer associated with osteoarthritis. Arthritis & Rheumatology, 73 (10). pp. 1856-1865. ISSN 2326-5191

Wilkinson, J.M. orcid.org/0000-0001-5577-3674 and Zeggini, E. (2021) The genetic epidemiology of joint shape and the development of osteoarthritis. Calcified Tissue International, 109 (3). pp. 257-276. ISSN 0171-967X

Penfold, C.M., Whitehouse, M.R., Blom, A.W. et al. (3 more authors) (2021) A comparison of comorbidity measures for predicting mortality after elective hip and knee replacement : a cohort study of data from the National Joint Registry in England and Wales. PLoS ONE, 16 (8). e0255602. ISSN 1932-6203

Steinberg, J., Southam, L., Fontalis, A. orcid.org/0000-0001-5547-288X et al. (8 more authors) (2021) Linking chondrocyte and synovial transcriptional profile to clinical phenotype in osteoarthritis. Annals of the Rheumatic Diseases, 80 (8). pp. 1070-1074. ISSN 0003-4967

Evans, J.T. orcid.org/0000-0002-9464-6261, Mouchti, S. orcid.org/0000-0002-3169-5242, Blom, A.W. et al. (4 more authors) (2021) Obesity and revision surgery, mortality, and patient-reported outcomes after primary knee replacement surgery in the National Joint Registry : a UK cohort study. PLoS Medicine, 18 (7). e1003704.

Mahatma, M.M., Jayasuriya, R.L., Hughes, D. et al. (8 more authors) (2021) Denosumab after total hip arthroplasty – Authors' reply. The Lancet Rheumatology, 3 (6). e406-e407. ISSN 2665-9913

Shah, K.M. orcid.org/0000-0001-9909-6409, Dunning, M.J. orcid.org/0000-0002-8853-9435, Gartland, A. orcid.org/0000-0002-3712-2437 et al. (1 more author) (2021) Distinct concentration-dependent molecular pathways regulate bone cell responses to cobalt and chromium exposure from joint replacement prostheses. International Journal of Molecular Sciences, 22 (10). 5225. ISSN 1661-6596

Hunt, L.P., Matharu, G.S., Blom, A.W. et al. (3 more authors) (2021) Patellar resurfacing during primary total knee replacement is associated with a lower risk of revision surgery. The Bone & Joint Journal, 103-B (5). pp. 864-871. ISSN 2049-4394

Silman, A.J., Combescure, C., Ferguson, R.J. et al. (12 more authors) (2021) International variation in distribution of ASA class in patients undergoing total hip arthroplasty and its influence on mortality: data from an international consortium of arthroplasty registries. Acta Orthopaedica, 92 (3). pp. 304-310. ISSN 1745-3674

Mahatma, M.M., Jayasuriya, R.L., Hughes, D. et al. (8 more authors) (2021) Effect of denosumab on osteolytic lesion activity after total hip arthroplasty: a single-centre, randomised, double-blind, placebo-controlled, proof of concept trial. The Lancet Rheumatology, 3 (3). e195-e203. ISSN 2665-9913

Boer, C.G., Yau, M.S., Rice, S.J. et al. (14 more authors) (2021) Genome-wide association of phenotypes based on clustering patterns of hand osteoarthritis identify WNT9A as novel osteoarthritis gene. Annals of the Rheumatic Diseases, 80 (3). pp. 367-375. ISSN 0003-4967

Steinberg, J., Southam, L., Roumeliotis, T.I. et al. (12 more authors) (2021) A molecular quantitative trait locus map for osteoarthritis. Nature Communications, 12. 1309. ISSN 2041-1723

Butterfield, N.C., Curry, K.F., Steinberg, J. et al. (24 more authors) (2021) Accelerating functional gene discovery in osteoarthritis. Nature Communications, 12 (1). 467. ISSN 2041-1723

Slullitel, P.A., Mahatma, M.M., Farzi, M. et al. (3 more authors) (2021) Influence of femoral component design on proximal femoral bone mass after total hip replacement : a randomized controlled trial. Journal of Bone and Joint Surgery, 103 (1). pp. 74-83. ISSN 0021-9355

Spain, L., Yang, L., Wilkinson, J.M. orcid.org/0000-0001-5577-3674 et al. (1 more author) (2020) Transmission of whole body vibration – comparison of three vibration platforms in healthy subjects. Bone, 144. 115802. ISSN 8756-3282

Ryan, M., Barnett, L., Rochester, J. et al. (2 more authors) (2020) A new approach to comprehensively evaluate the morphological properties of the human femoral head : example of application to osteoarthritic joint. Scientific Reports, 10 (1). 5538.

Trela-Larsen, L., Kroken, G., Bartz-Johannessen, C. et al. (8 more authors) (2020) Personalized estimation of one-year mortality risk after elective hip or knee arthroplasty for osteoarthritis. Bone & Joint Research, 9 (11). pp. 808-820.

Ryan, M.K., Oliviero, S., Costa, M.C. et al. (2 more authors) (2020) Heterogeneous strain distribution in the subchondral bone of human osteoarthritic femoral heads, measured with digital volume correlation. Materials, 13 (20). 4619.

Zotov, E., Hills, A.F. orcid.org/0000-0002-6849-6116, de Mello, F.L. et al. (6 more authors) (2020) JointCalc: A web-based personalised patient decision support tool for joint replacement. International Journal of Medical Informatics, 142. 104217. ISSN 1386-5056

Boulton, C. and Wilkinson, J.M. orcid.org/0000-0001-5577-3674 (2020) Use of public datasets in the examination of multimorbidity: opportunities and challenges. Mechanisms of Ageing and Development, 190. 111310. ISSN 0047-6374

Wilkinson, J.M. (2020) The use of bisphosphonates to meet orthopaedic challenges. Bone, 137. 115443. ISSN 8756-3282

Farzi, M., Pozo, J.M., McCloskey, E. orcid.org/0000-0003-0177-8140 et al. (4 more authors) (2020) A spatio-temporal ageing atlas of the proximal femur. IEEE Transactions on Medical Imaging, 39 (5). pp. 1359-1368. ISSN 0278-0062

Lefley, D., Howard, F., Arshad, F. et al. (9 more authors) (2019) Development of clinically relevant in vivo metastasis models using human bone discs and breast cancer patient-derived xenografts. Breast Cancer Research, 21 (1). 130. ISSN 1465-5411

Penfold, C.M. orcid.org/0000-0001-8654-353X, Blom, A.W., Sayers, A. orcid.org/0000-0001-7452-5043 et al. (4 more authors) (2019) Understanding the uptake of new hip replacement implants in the UK: a cohort study using data from the National Joint Registry for England and Wales. BMJ Open, 9 (11). e029572.

Duckworth, A.D., McQueen, M.M., Tuck, C.E. et al. (19 more authors) (2019) Effect of alendronic acid on fracture healing: A multicenter randomized placebo-controlled trial. Journal of Bone and Mineral Research, 34 (6). pp. 1025-1032. ISSN 0884-0431

Wilkinson, J.M. orcid.org/0000-0001-5577-3674 (2019) The hip arthroplasty journey : where are we going and who is paying the bill? Bone and Joint Research, 8 (6). pp. 224-225. ISSN 2046-3758

Porter, M., Armstrong, R., Howard, P. et al. (2 more authors) (2019) Orthopaedic registries - the UK view (National Joint Registry) : impact on practice. EFORT Open Reviews, 4 (6). pp. 377-390. ISSN 2396-7544

Tulotta, C., Lefley, D.V., Freeman, K. et al. (16 more authors) (2019) Endogenous production of IL-1B by breast cancer cells drives metastasis and colonisation of the bone microenvironment. Clinical Cancer Research, 25 (9). pp. 2769-2782. ISSN 1078-0432

MacInnes, S.J., Hatzikotoulas, K., Fenstad, A.M. et al. (9 more authors) (2019) The 2018 Otto Aufranc Award: How does genome-wide variation affect osteolysis risk after THA? Clinical Orthopaedics and Related Research, 477 (2). pp. 297-309. ISSN 0009-921X

Tachmazidou, I., Hatzikotoulas, K. orcid.org/0000-0002-4699-3672, Southam, L. orcid.org/0000-0002-7546-9650 et al. (19 more authors) (2019) Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. Nature Genetics, 51. pp. 230-236. ISSN 1061-4036

Johnstone, B., Jacobs, J.J., Sandell, L.J. et al. (1 more author) (2018) Regenerative Medicine Will Make Orthopaedic Implants Obsolete In Our Time Orthopaedic Research Society First Annual Meeting Debate, San Diego, March 21st , 2017. Journal of Orthopaedic Research, 36 (10). pp. 2579-2585. ISSN 0736-0266

Aram, P., Trela-Larsen, L., Sayers, A. et al. (5 more authors) (2018) Estimating an individual's probability of revision surgery after knee replacement : a comparison of modeling approaches using a national dataset. American Journal of Epidemiology, 187 (10). pp. 2252-2262. ISSN 0002-9262

Metcalfe, D., Peterson, N., Wilkinson, J.M. orcid.org/0000-0001-5577-3674 et al. (1 more author) (2018) Temporal trends and survivorship of total hip arthroplasty in very young patients. Bone and Joint Journal, 100-B (10). pp. 1320-1329. ISSN 2049-4394

Steinberg, J., Brooks, R.A., Southam, L. et al. (8 more authors) (2018) Widespread epigenomic, transcriptomic and proteomic differences between hip osteophytic and articular chondrocytes in osteoarthritis. Rheumatology, 57 (8). pp. 1481-1489. ISSN 1462-0324

Hatzikotoulas, K. orcid.org/0000-0002-4699-3672, Roposch, A., Case Control Consortium, D.D.H. et al. (14 more authors) (2018) Genome-wide association study of developmental dysplasia of the hip identifies an association with GDF5. Communications Biology, 1. 56. ISSN 2399-3642

Casalone, E., Tachmazidou, I., Zengini, E. et al. (9 more authors) (2018) A novel variant in GLIS3 is associated with osteoarthritis. Annals of the Rheumatic Diseases, 77 (4). pp. 620-622. ISSN 0003-4967

Zengini, E., Hatzikotoulas, K., Tachmazidou, I. et al. (20 more authors) (2018) Genome-wide analyses using UK Biobank data provide insights into the genetic architecture of osteoarthritis. Nature Genetics, 50 (4). pp. 549-558. ISSN 1061-4036

Sabah, S.A., Moon, J.C., Jenkins-Jones, S. et al. (11 more authors) (2018) The risk of cardiac failure following metal-on-metal hip arthroplasty. Bone and Joint Journal, 100B. pp. 20-27. ISSN 2049-4394

Hunt, L.P., Blom, A. and Wilkinson, J.M. orcid.org/0000-0001-5577-3674 (2017) An analysis of 30-day mortality after weekend versus weekday elective joint arthroplasty in England and Wales: a cohort study using the National Joint Registry Dataset. Bone and Joint Journal , 99-B (12). pp. 1618-1628. ISSN 2049-4394

Hackinger, S., Trajanoska, K., Styrkarsdottir, U. et al. (19 more authors) (2017) Evaluation of shared genetic aetiology between osteoarthritis and bone mineral density identifies SMAD3 as a novel osteoarthritis risk locus. Human Molecular Genetics, 26 (19). pp. 3850-3858. ISSN 0964-6906

Cibrián Uhalte, E., Wilkinson, J.M. orcid.org/0000-0001-5577-3674, Southam, L. et al. (1 more author) (2017) Pathways to understanding the genomic aetiology of osteoarthritis. Human Molecular Genetics, 26 (R2). R193-R201. ISSN 0964-6906

Steinberg, J., Ritchie, G.R.S., Roumeliotis, T.I. et al. (15 more authors) (2017) Integrative epigenomics, transcriptomics and proteomics of patient chondrocytes reveal genes and pathways involved in osteoarthritis. Scientific Reports, 7 (1). 8935. ISSN 2045-2322

Shah, K.M., Orton, P., Mani, N. et al. (2 more authors) (2017) Osteocyte physiology and response to fluid shear stress are impaired following exposure to cobalt and chromium: Implications for bone health following joint replacement. Journal of Orthopaedic Research, 35 (8). pp. 1716-1723. ISSN 0736-0266

Parker, A.M., Yang, L., Farzi, M. et al. (3 more authors) (2017) Quantifying Pelvic Periprosthetic Bone Remodeling Using Dual-Energy X-Ray Absorptiometry Region-Free Analysis. Journal of Clinical Densitometry. ISSN 1094-6950

Farzi, M., Morris, R.M., Penny, J. et al. (5 more authors) (2017) Quantitating the effect of prosthesis design on femoral remodeling using high-resolution region-free densitometric analysis (DXA-RFA). Journal of Orthopaedic Research. ISSN 0736-0266

Smith, M.C., Ben-Shlomo, Y., Dieppe, P. et al. (3 more authors) (2017) Rates of hip and knee joint replacement amongst different ethnic groups in England: an analysis of National Joint Registry data. Osteoarthritis and Cartilage. ISSN 1063-4584

Steinberg, J., Shah, K.M., Gartland, A. orcid.org/0000-0002-3712-2437 et al. (2 more authors) (2017) The effects of chronic cobalt and chromium exposure after metal-on-metal hip resurfacing: An epigenome-wide association pilot study. Journal of Orthopaedic Research. ISSN 0736-0266

Panoutsopoulou, K., Thiagarajah, S., Zengini, E. et al. (12 more authors) (2016) Radiographic endophenotyping in hip osteoarthritis improves the precision of genetic association analysis. Annals of the Rheumatic Diseases. ISSN 0003-4967

King, G., Hunt, L.P., Wilkinson, J.M. orcid.org/0000-0001-5577-3674 et al. (1 more author) (2016) Good outcome of total hip replacement in patients with cerebral palsy. Acta Orthopaedica, 87 (2). pp. 93-99. ISSN 1745-3674

Dunn, S.L., Wilkinson, J.M. orcid.org/0000-0001-5577-3674, Crawford, A. et al. (2 more authors) (2016) Expression of Cannabinoid Receptors in Human Osteoarthritic Cartilage: Implications for Future Therapies. Cannabis and Cannabinoid Research, 1 (1). pp. 3-15. ISSN 2378-8763

Holen, I., Nutter, F., Wilkinson, J.M. et al. (3 more authors) (2015) Human breast cancer bone metastasis in vitro and in vivo: a novel 3D model system for studies of tumour cell-bone cell interactions. Clinical & Experimental Metastasis, 32 (7). 689 - 702. ISSN 0262-0898

Lindner, C., Thiagarajah, S., Wilkinson, J.M. orcid.org/0000-0001-5577-3674 et al. (5 more authors) (2015) Investigation of Association Between Hip Osteoarthritis Susceptibility Loci and Radiographic Proximal Femur Shape. Arthritis & Rheumatology, 67 (8). pp. 2076-2084. ISSN 2326-5191

Hawtree, S., Muthana, M., Wilkinson, J.M. et al. (2 more authors) (2015) Histone deacetylase 1 regulates tissue destruction in rheumatoid arthritis. Human Molecular Genetics, 24 (19). pp. 5367-5377. ISSN 0964-6906

Wilkinson, J.M., Morris, R.M., Martin-Fernandez, M.A. et al. (4 more authors) (2015) Use of high resolution dual-energy x-ray absorptiometry-region free analysis (DXA-RFA) to detect local periprosthetic bone remodeling events. Journal of Orthopaedic Research, 33 (5). 712 - 716.

Shah, K.M., Wilkinson, J.M. and Gartland, A. (2015) Cobalt and chromium exposure affects osteoblast function and impairs the mineralization of prosthesis surfaces in vitro. Journal of Orthopaedic Research.

Morris, R.M., Yang, L., Martin-Fernandez, M.A. et al. (3 more authors) (2015) High-Spatial-Resolution Bone Densitometry with Dual-Energy X-ray Absorptiometric Region-free Analysis. Radiology, 274 (2). 532 - 539. ISSN 0033-8419

Evangelou, E., Kerkhof, H.J., Styrkarsdottir, U. et al. (64 more authors) (2014) A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip. Annals of the Rheumatic Diseases (ARD), 73 (12). pp. 2130-2136. ISSN 0003-4967

Rodriguez-Fontenla, C., Calaza, M., Evangelou, E. et al. (45 more authors) (2014) Assessment of Osteoarthritis Candidate Genes in a Meta-Analysis of Nine Genome-Wide Association Studies. Arthritis & Rheumatology, 66 (4). pp. 940-949. ISSN 2326-5191

Prentice, J.R., Blackwell, C.S., Raoof, N. et al. (4 more authors) (2014) Auditory and Visual Health after Ten Years of Exposure to Metal-on-Metal Hip Prostheses: A Cross-Sectional Study Follow Up. PLOS One, 9 (3). e90838. ISSN 1932-6203

Aram, P., Kadirkamanathan, V. and Wilkinson, J.M. (2013) Use of kernel-based Bayesian models to predict late osteolysis after hip replacement. Interface, 10 (88). ISSN 1742-5689

Kiss-Toth, E., Harlock, E., Lath, D. et al. (2 more authors) (2013) A TNF Variant that Associates with Susceptibility to Musculoskeletal Disease Modulates Thyroid Hormone Receptor Binding to Control Promoter Activation. PLOS One, 8 (9). e76034. ISSN 1932-6203

Prentice, J.R., Clark, M.J., Hoggard, N. et al. (6 more authors) (2013) Metal-on-Metal Hip Prostheses and Systemic Health: A Cross-Sectional Association Study 8 Years after Implantation. PLOS One, 8 (6). e66186. ISSN 1932-6203

Hudson, G., Panoutsopoulou, K., Wilson, I. et al. (22 more authors) (2013) No evidence of an association between mitochondrial DNA variants and osteoarthritis in 7393 cases and 5122 controls. Annals of the Rheumatic Diseases (ARD), 72 (1). pp. 136-139. ISSN 0003-4967

Southam, L., Panoutsopoulou, K., Rayner, N.W. et al. (18 more authors) (2011) The effect of genome-wide association scan quality control on imputation outcome for common variants. European Journal of Human Genetics, 19 (5). pp. 610-614.

Andrews, R.E., Shah, K.M., Wilkinson, J.M. et al. (1 more author) (2011) Effects of cobalt and chromium ions at clinically equivalent concentrations after metal-on-metal hip replacement on human osteoblasts and osteoclasts: implications for skeletal health. Bone, 49 (4). pp. 717-723. ISSN 8756-3282

Panoutsopoulou, K., Southam, L., Elliott, K.S. et al. (73 more authors) (2010) Insights into the genetic architecture of osteoarthritis from stage 1 of the arcOGEN study. Annals of the Rheumatic Diseases (ARD), 70 (5). pp. 864-867. ISSN 0003-4967

Proceedings Paper

Strauss, V.Y., Prats-Uribe, A., Berencsi, K. et al. (13 more authors) (2019) Propensity score stratification and inverse probability weighting compared to surgical randomized clinical trial results in device epidemiology. In: Pharmacoepidemiology and Drug Safety. 35th International Conference on Pharmacoepidemiology & Therapeutic Risk Management, 24-28 Aug 2019, Philadelphia, PA, USA. Wiley , p. 431.

Prats-Uribe, A., Berencsi, K., Carr, A. et al. (13 more authors) (2019) The performance of preference-based instrumental variables to emulate a randomized clinical trial of comparative medical device effectiveness. In: Pharmacoepidemiology and Drug Safety. 35th International Conference on Pharmacoepidemiology & Therapeutic Risk Management, 24-28 Aug 2019, Philadelphia, PA, USA. Wiley , pp. 431-432.

Hatzikotoulas, K., Roposch, A., Shah, K.M. et al. (13 more authors) (2017) National clinical audit data decodes the genetic architecture of developmental dysplasia of the hip. In: Osteoarthritis and Cartilage. 2017 OARSI World Congress on Osteoarthritis: Promoting Clinical and Basic Research in Osteoarthritis, 27-30 April 2017, Las Vegas, USA. Elsevier , S36-S37.

This list was generated on Sat Jul 2 10:09:31 2022 BST.