Items where authors include "Vile, R"

Article

Annels, NE, Arif, M, Simpson, GR et al. (11 more authors) (2018) Oncolytic Immunotherapy for Bladder Cancer Using Coxsackie A21 Virus. Molecular Therapy - Oncolytics, 9. C. pp. 1-12. ISSN 2372-7705

Samson, A orcid.org/0000-0002-3081-7850, Bentham, MJ orcid.org/0000-0003-2439-3198, Scott, K orcid.org/0000-0002-5790-9579 et al. (15 more authors) (2018) Oncolytic reovirus as a combined antiviral and anti-tumour agent for the treatment of liver cancer. Gut, 67 (3). pp. 562-573. ISSN 0017-5749

Kottke, T, Evgin, L, Shim, KG et al. (12 more authors) (2017) Subversion of NK-cell and TNFα Immune Surveillance Drives Tumor Recurrence. Cancer Immunology Research, 5 (11). pp. 1029-1045. ISSN 2326-6066

Cockle, JV, Brüning-Richardson, A orcid.org/0000-0002-9862-9805, Scott, KJ orcid.org/0000-0002-5790-9579 et al. (13 more authors) (2017) Oncolytic Herpes Simplex Virus Inhibits Pediatric Brain Tumor Migration and Invasion. Molecular Therapy - Oncolytics, 5. pp. 75-86. ISSN 2372-7705

Ilett, E, Kottke, T, Thompson, J et al. (12 more authors) (2017) Prime-boost using separate oncolytic viruses in combination with checkpoint blockade improves anti-tumor therapy. Gene Therapy, 24 (1). pp. 21-30. ISSN 0969-7128

Kottke, T, Shim, KG, Alonso-Camino, V et al. (12 more authors) (2016) Immunogenicity of self tumor associated proteins is enhanced through protein truncation. Molecular Therapy - Oncolytics, 3. 16030.

Sun, CW, Willmon, C, Wu, L-C et al. (5 more authors) (2016) Sickle Cells Abolish Melanoma Tumorigenesis in Hemoglobin SS Knockin Mice and Augment the Tumoricidal Effect of Oncolytic Virus In Vivo. Frontiers in Oncology, 6 (166). ISSN 2234-943X

Cockle, JV, Rajani, K, Zaidi, S et al. (11 more authors) (2016) Combination viroimmunotherapy with checkpoint inhibition to treat glioma, based on location-specific tumor profiling. Neuro-Oncology, 18 (4). pp. 518-527. ISSN 1523-5866

Rajani, K, Parrish, C, Kottke, T et al. (10 more authors) (2016) Combination therapy with reovirus and anti-PD-1 blockade controls tumor growth through innate and adaptive immune responses. Molecular Therapy, 24 (1). pp. 166-174. ISSN 1525-0016

Roulstone, V, Pedersen, M, Kyula, J et al. (14 more authors) (2015) BRAF- and MEK-targeted small molecule inhibitors exert enhanced antimelanoma effects in combination with oncolytic reovirus through ER stress. Molecular Therapy, 23 (5). pp. 931-942. ISSN 1525-0016

Roulstone, V, Khan, K, Pandha, HS et al. (8 more authors) (2015) Phase I trial of cyclophosphamide as an immune modulator for optimizing oncolytic reovirus delivery to solid tumors. Clinical Cancer Research, 21 (6). 1305 - 1312. ISSN 1078-0432

Seth, R, Khan, AA, Pencavel, TD et al. (8 more authors) (2015) Adenovirally Delivered Enzyme Prodrug Therapy with Herpes Simplex Virus-Thymidine Kinase in Composite Tissue Free Flaps Shows Therapeutic Efficacy in Rat Models of Glioma. Plastic and Reconstructive Surgery, 135 (2). 475 - 487. ISSN 0032-1052

Zaidi, S, Blanchard, M, Shim, K et al. (13 more authors) (2015) Mutated BRAF emerges as a major effector of recurrence in a murine melanoma model after treatment with immunomodulatory agents. Molecular Therapy, 23 (5). 845 - 856. ISSN 1525-0016

Ilett, E orcid.org/0000-0002-9875-0322, Kottke, T, Donnelly, O et al. (10 more authors) (2014) Cytokine Conditioning Enhances Systemic Delivery and Therapy of an Oncolytic Virus. Molecular Therapy, 22 (10). pp. 1851-1863. ISSN 1525-0016

Alonso-Camino, V, Rajani, K, Kottke, T et al. (12 more authors) (2014) The Profile of Tumor Antigens Which Can be Targeted by Immunotherapy Depends Upon the Tumor's Anatomical Site. Molecular Therapy, 22 (11). 1936 - 1948. ISSN 1525-0016

Jennings, V, Ilett, EJ orcid.org/0000-0002-9875-0322, Scott, K orcid.org/0000-0002-5790-9579 et al. (10 more authors) (2014) Lymphokine-activated killer and dendritic cell carriage enhances oncolytic reovirus therapy for ovarian cancer by overcoming antibody neutralization in ascites. International Journal of Cancer, 134 (5). pp. 1091-1101. ISSN 0020-7136

Kottke, T, Boisgerault, N, Diaz, RM et al. (12 more authors) (2013) Detecting and targeting tumor relapse by its resistance to innate effectors at early recurrence. Nature Medicine, 19. 1625 - 1631. ISSN 1078-8956

Boisgerault, N, Kottke, T, Pulido, J et al. (11 more authors) (2013) Functional Cloning of Recurrence-specific Antigens Identifies Molecular Targets to Treat Tumor Relapse. Molecular Therapy, 21 (8). 1507 - 1516. ISSN 1525-0016

Donnelly, O, Vile, R, Pandha, H et al. (2 more authors) (2012) The hitchhiker's guide to virotherapy. Oncotarget, 3 (8). pp. 735-736. ISSN 1949-2553

Hall, K, Scott, KJ, Rose, A et al. (9 more authors) (2012) Reovirus-mediated cytotoxicity and enhancement of innate immune responses against acute myeloid leukemia. BioResearch Open Access, 1 (1). pp. 3-15. ISSN 2164-7844

Kottke, T, Errington, F orcid.org/0000-0003-2155-534X, Pulido, J et al. (12 more authors) (2011) Broad antigenic coverage induced by vaccination with virus-based cDNA libraries cures established tumors. Nature Medicine, 17 (7). pp. 854-859. ISSN 1078-8956

Heinemann, L, Simpson, GR, Boxall, A et al. (8 more authors) (2011) Synergistic effects of oncolytic reovirus and docetaxel chemotherapy in prostate cancer. BMC Cancer, 11 (1). ARTN 221. ISSN 1471-2407

Steele, L, Errington, F orcid.org/0000-0003-2155-534X, Prestwich, R et al. (7 more authors) (2011) Pro-inflammatory cytokine/chemokine production by reovirus treated melanoma cells is PKR/NF-κB mediated and supports innate and adaptive anti-tumour immune priming. Molecular Cancer, 10 (1). 20. ISSN 1476-4598

Galivo, F, Diaz, RM, Wongthida, P et al. (5 more authors) (2010) Single-cycle viral gene expression, rather than progressive replication and oncolysis, is required for VSV therapy of B16 melanoma. Gene Therapy, 17 (2). pp. 158-170. ISSN 1476-5462

Merrick, AE, Errington, F orcid.org/0000-0003-2155-534X, Milward, K et al. (8 more authors) (2005) Immunosuppressive effects of radiation on human dendritic cells: reduced IL-12 production on activation and impairment of naïve T-cell priming. British Journal of Cancer, 92 (8). pp. 1450-1458. ISSN 0007-0920

Proceedings Paper

Schuelke, M, Evgin, L, Kottke, T et al. (8 more authors) (2016) Balancing Anti-Tumor Efficacy with Local Inflammatory Toxicity for the Treatment of Diffuse Intrinsic Pontine Glioma and Other Brain Tumors. In: Molecular Therapy. 19th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 04-07 May 2016, Washington DC, USA. Nature Publishing Group , S77-S77.

Kottke, T, Rommelfanger, D, Shim, KG et al. (8 more authors) (2016) Escape from Tumor Dormancy Following Gene- or Viro-Therapies Is Mediated by Acquisition of a Phenotype in Which Innate Immune Surveillance Actively Drives Tumor Cell Recurrence. In: Molecular Therapy. 19th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 04-07 May 2016, Washington DC, USA. Nature Publishing Group , S296-S296.

Kottke, T, Shim, KG, Evgin, L et al. (13 more authors) (2016) Immunogenicity of Self Tumor Associated Antigens Is Enhanced Through Protein Truncation. In: Molecular Therapy. 19th Annual Meeting of the American-Society-of-Gene-and-Cell-Therapy (ASGCT), 04-07 May 2016, Washington DC, USA. Nature Publishing Group , S28-S28.

Alonso-Camino, V, Rajani, K, Kottke, T et al. (11 more authors) (2014) The Profile of Tumor Antigens Which Can Be Targeted By Immunotherapy Depends Upon the Tumor's Anatomical Site. In: Molecular Therapy. 7th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT), 21-24 May 2014, Washington, DC, USA. Nature Publishing Group , S200-S200.