Items where authors include "Tucker, Julie Ann"

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Article

Miller, Duncan C., Reuillon, Tristan, Molyneux, Lauren et al. (23 more authors) (2022) Parallel Optimisation of Potency and Pharmacokinetics Leading to the Discovery of a Pyrrole Carboxamide ERK5 Chemical Tool. JOURNAL OF MEDICINAL CHEMISTRY. pp. 6513-6540. ISSN 0022-2623

Al-Khawaldeh, Islam, Alyassiri, Mohammed, Aldred, Greg et al. (29 more authors) (2021) An alkynylpyrimidine-based covalent inhibitor that targets a unique cysteine in NF-κB-inducing kinase (NIK). JOURNAL OF MEDICINAL CHEMISTRY. 10001–10018. ISSN 0022-2623

Tucker, Julie Ann orcid.org/0000-0002-6119-676X and Martin, Mathew P. (2021) Recent Advances in Kinase Drug Discovery Part I: the Editors’ Take. International Journal of Molecular Sciences. pp. 1-6. ISSN 1422-0067

Cook, Simon, Tucker, Julie Ann orcid.org/0000-0002-6119-676X and Lochhead, Pamela (2020) Small molecule ERK5 kinase inhibitors paradoxically activate ERK5 signalling: be careful what you wish for... Biochemical Society transactions. ISSN 1470-8752

Lochhead, Pamela, Tucker, Julie Ann orcid.org/0000-0002-6119-676X, Tatum, Natalie et al. (8 more authors) (2020) Paradoxical activation of the protein kinase-transcription factor ERK5 by ERK5 kinase inhibitors. Nature Communications. 1383. ISSN 2041-1723

Wilmes, Stephan, Hafer, Maximillian, Vuorio, Joni et al. (15 more authors) (2020) Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations. Science. pp. 643-652. ISSN 0036-8075

Tucker, Julie Ann orcid.org/0000-0002-6119-676X, Myers, Stephanie M., Miller, Duncan C. et al. (27 more authors) (2019) Identification of a novel orally bioavailable ERK5 inhibitor with selectivity over p38α and BRD4. European Journal of Medicinal Chemistry. pp. 530-543. ISSN 0223-5234

Waszkowycz, Bohdan, Smith, Kate M., McGonagle, Alison E. et al. (17 more authors) (2018) Cell-active Small Molecule Inhibitors of the DNA-damage Repair Enzyme Poly(ADP-ribose) Glycohydrolase (PARG) : Discovery and Optimization of Orally Bioavailable Quinazolinedione Sulfonamides. JOURNAL OF MEDICINAL CHEMISTRY. pp. 10767-10792. ISSN 0022-2623

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