Items where authors include "Stewart, PM"

Article

Mahida, RY, Lax, S, Bassford, CR et al. (9 more authors) (2023) Impaired alveolar macrophage 11β-hydroxysteroid dehydrogenase type 1 reductase activity contributes to increased pulmonary inflammation and mortality in sepsis-related ARDS. Frontiers in Immunology, 14. 1159831. ISSN 1664-3224

Othonos, N, Pofi, R, Arvaniti, A et al. (28 more authors) (2023) 11β-HSD1 inhibition in men mitigates prednisolone-induced adverse effects in a proof-of-concept randomised double-blind placebo-controlled trial. Nature Communications, 14 (1). 1025. ISSN 2041-1723

Elhassan, YS, Iqbal, F, Arlt, W et al. (7 more authors) (2023) COVID-19-related adrenal haemorrhage: Multicentre UK experience and systematic review of the literature. Clinical Endocrinology. ISSN 0300-0664

Morgan, SA, Gathercole, LL, Hassan-Smith, ZK et al. (3 more authors) (2022) 11β-HSD1 contributes to age-related metabolic decline in male mice. Journal of Endocrinology, 255 (3). pp. 117-129. ISSN 0022-0795

Limumpornpetch, P, Morgan, AW orcid.org/0000-0003-1109-624X, Tiganescu, A orcid.org/0000-0003-3688-2204 et al. (4 more authors) (2022) The effect of endogenous Cushing's syndrome on all-cause and cause-specific mortality: A systematic review and meta-analysis. Journal of Clinical Endocrinology and Metabolism, 107 (8). dgac265. pp. 2377-2388. ISSN 0021-972X

Abbas, A, Schini, M, Ainsworth, G orcid.org/0000-0002-9952-8440 et al. (7 more authors) (2022) Effect of AZD4017, a Selective 11β-HSD1 Inhibitor, on Bone Turnover Markers in Postmenopausal Osteopenia. Journal of Clinical Endocrinology and Metabolism. ISSN 0021-972X

Ajjan, RA, Hensor, EMA, Del Galdo, F et al. (13 more authors) (2022) Oral 11β-HSD1 inhibitor AZD4017 improves wound healing and skin integrity in adults with type 2 diabetes mellitus: a pilot randomised controlled trial. European Journal of Endocrinology. ISSN 0804-4643

Morgan, SA, Berryman, DE, List, EO et al. (3 more authors) (2022) Regulation of 11β-HSD1 by GH/IGF-1 in key metabolic tissues may contribute to metabolic disease in GH deficient patients. Growth Hormone and IGF Research, 62. 101440. ISSN 1096-6374

Stewart, PM orcid.org/0000-0002-1749-9640, Mirmira, RG and Kaiser, UB (2021) Environmental Pollution, Climate Change, and a Critical Role for the Endocrinologist. Journal of Clinical Endocrinology and Metabolism, 106 (12). pp. 3381-3384. ISSN 0021-972X

Espiard, S, McQueen, J, Sherlock, M et al. (10 more authors) (2021) Improved Urinary Cortisol Metabolome in Addison Disease: A Prospective Trial of Dual-Release Hydrocortisone. Journal of Clinical Endocrinology and Metabolism, 106 (3). pp. 814-825. ISSN 0021-972X

Threapleton, DE orcid.org/0000-0002-5884-3372, Snart, CJP, Keeble, C orcid.org/0000-0003-1633-8842 et al. (18 more authors) (2021) Maternal iodine status in a multi-ethnic UK birth cohort: Associations with child cognitive and educational development. Paediatric and Perinatal Epidemiology, 35 (2). pp. 236-246. ISSN 0269-5022

Threapleton, DE orcid.org/0000-0002-5884-3372, Waiblinger, D, Snart, CJP et al. (18 more authors) (2021) Prenatal and Postpartum Maternal Iodide Intake from Diet and Supplements, Urinary Iodine and Thyroid Hormone Concentrations in a Region of the United Kingdom with Mild-to-Moderate Iodine Deficiency. Nutrients, 13 (1). 230. ISSN 2072-6643

Hardy, RS, Botfield, H, Markey, K et al. (16 more authors) (2021) 11βHSD1 Inhibition with AZD4017 Improves Lipid Profiles and Lean Muscle Mass in Idiopathic Intracranial Hypertension. Journal of Clinical Endocrinology and Metabolism, 106 (1). pp. 174-187. ISSN 0021-972X

Sherlock, M, Scarsbrook, A orcid.org/0000-0002-4243-032X, Abbas, A et al. (4 more authors) (2020) Adrenal Incidentaloma. Endocrine Reviews, 41 (6). pp. 775-820. ISSN 0163-769X

Cromie, KJ orcid.org/0000-0002-2859-5291, Threapleton, DE orcid.org/0000-0002-5884-3372, Snart, CJP et al. (20 more authors) (2020) Maternal iodine status in a multi-ethnic UK birth cohort: associations with autism spectrum disorder. BMC Pediatrics, 20 (1). 544. ISSN 1471-2431

Dineen, R, Behan, L-A, Kelleher, G et al. (12 more authors) (2020) The contribution of serum cortisone and glucocorticoid metabolites to detrimental bone health in patients receiving hydrocortisone therapy. BMC Endocrine Disorders, 20. 154.

Snart, CJP, Threapleton, DE orcid.org/0000-0002-5884-3372, Keeble, C orcid.org/0000-0003-1633-8842 et al. (18 more authors) (2020) Maternal iodine status, intrauterine growth, birth outcomes and congenital anomalies in a UK birth cohort. BMC Medicine, 18. 132. ISSN 1741-7015

Kaiser, UB, Mirmira, RG and Stewart, PM orcid.org/0000-0002-1749-9640 (2020) Our Response to COVID-19 as Endocrinologists and Diabetologists. The Journal of Clinical Endocrinology & Metabolism, 105 (5). pp. 1299-1301. ISSN 0021-972X

Mebrahtu, TF orcid.org/0000-0003-4821-2304, Morgan, AW orcid.org/0000-0003-1109-624X, West, RM orcid.org/0000-0001-7305-3654 et al. (2 more authors) (2020) Oral glucocorticoids and incidence of hypertension in people with chronic inflammatory diseases: a population-based cohort study. Canadian Medical Association Journal, 192 (12). E295-E301. ISSN 0008-4409

Markey, K, Mitchell, J, Botfield, H et al. (22 more authors) (2020) 11β-Hydroxysteroid dehydrogenase type 1 inhibition in idiopathic intracranial hypertension: a double-blind randomized controlled trial. Brain Communications, 2 (1). fcz050.

Mebrahtu, T orcid.org/0000-0003-4821-2304, Morgan, AW orcid.org/0000-0003-1109-624X, Keeley, A et al. (3 more authors) (2019) Dose dependency of iatrogenic glucocorticoid excess and adrenal insufficiency and mortality: a cohort study in England. Journal of Clinical Endocrinology and Metabolism, 104 (9). jc.2019-00153. pp. 3757-3767. ISSN 0021-972X

Crowley, RK, Woods, CP, Hughes, BA et al. (9 more authors) (2019) Increased central adiposity and decreased subcutaneous adipose tissue 11β‐hydroxysteroid dehydrogenase type 1 are associated with deterioration in glucose tolerance—A longitudinal cohort study. Clinical Endocrinology, 91 (1). pp. 72-81. ISSN 0300-0664

Stewart, PM orcid.org/0000-0002-1749-9640 (2019) Modified-Release Hydrocortisone: Is It Time to Change Clinical Practice? Journal of the Endocrine Society, 3 (6). pp. 1150-1153. ISSN 2472-1972

Snart, CJP, Keeble, C, Taylor, E et al. (10 more authors) (2019) Maternal Iodine Status and Associations with Birth Outcomes in Three Major Cities in the United Kingdom. Nutrients, 11 (2). 441. ISSN 2072-6643

Dineen, R, Stewart, PM orcid.org/0000-0002-1749-9640 and Sherlock, M (2019) Factors impacting on the action of glucocorticoids in patients receiving glucocorticoid therapy. Clinical Endocrinology, 90 (1). pp. 3-14. ISSN 0300-0664

Sherlock, M and Stewart, PM orcid.org/0000-0002-1749-9640 (2019) The Short Synacthen Test and Its Utility in Assessing Recovery of Adrenal Function in Patients With Central Adrenal Insufficiency. Journal of Clinical Endocrinology and Metabolism, 104 (1). pp. 17-20. ISSN 0021-972X

Doig, CL, Fletcher, RS, Morgan, SA et al. (6 more authors) (2017) 11β-HSD1 Modulates the Set Point of Brown Adipose Tissue Response to Glucocorticoids in Male Mice. Endocrinology, 158 (6). pp. 1964-1976. ISSN 0013-7227

Gunnarsson, C, Ryan, MP, Marelli, C et al. (4 more authors) (2017) Health Care Burden in Patients With Adrenal Insufficiency. Journal of the Endocrine Society, 1 (5). pp. 512-523.

Weigel, M, Hahner, S, Sherlock, M et al. (8 more authors) (2017) Immediate versus modified release hydrocortisone in mitotane-treated patients with adrenocortical cancer. Clinical Endocrinology, 86 (4). pp. 499-505. ISSN 0300-0664

Hassan-Smith, ZK, Jenkinson, C, Smith, DJ et al. (7 more authors) (2017) 25-hydroxyvitamin D3 and 1,25-dihydroxyvitamin D3 exert distinct effects on human skeletal muscle function and gene expression. PLoS ONE, 12 (2). e0170665.

Hardy, RS, Doig, CL, Hussain, Z et al. (11 more authors) (2016) 11β-Hydroxysteroid dehydrogenase type 1 within muscle protects against the adverse effects of local inflammation. Journal of Pathology, 240 (4). pp. 472-483. ISSN 0022-3417

Stewart, PM orcid.org/0000-0002-1749-9640, Biller, BMK, Marelli, C et al. (3 more authors) (2016) Exploring Inpatient Hospitalizations and Morbidity in Patients With Adrenal Insufficiency. Journal of Clinical Endocrinology & Metabolism, 101 (12). pp. 4843-4850. ISSN 0021-972X

Woods, CP, Crowley, RK, Gathercole, LL et al. (6 more authors) (2016) Changes in adipose tissue gene expression profile and fat mass are associated with deteriorating glucose tolerance. Irish Journal of Medical Science, 185 (Supplement 7). S372-S372. ISSN 0021-1265

Crowley, RK, O’Reilly, MW, Bujalska, IJ et al. (5 more authors) (2016) SFRP2 Is Associated with Increased Adiposity and VEGF Expression. PLoS ONE, 11 (9). e0163777. ISSN 1932-6203

Larner, DP, Morgan, SA, Gathercole, LL et al. (7 more authors) (2016) Male 11β-HSD1 knockout mice fed trans-fats and fructose are not protected from metabolic syndrome or non-alcoholic fatty liver disease. Endocrinology, 157 (9). pp. 3493-3504. ISSN 0013-7227

Clayton, RN, Jones, PW, Reulen, RC et al. (9 more authors) (2016) Mortality in patients with Cushing's disease more than 10 years after remission: A multicentre, multinational, retrospective cohort study. The Lancet Diabetes and Endocrinology, 4 (7). pp. 569-576. ISSN 2213-8587

Morgan, SA, Hassan-Smith, ZK, Doig, CL et al. (3 more authors) (2016) Glucocorticoids and 11β-HSD1 are major regulators of intramyocellular protein metabolism. Journal of Endocrinology, 229 (3). pp. 277-286. ISSN 0022-0795

Woods, CP, Argese, N, Chapman, M et al. (9 more authors) (2015) Adrenal suppression in patients taking inhaled glucocorticoids is highly prevalent and management can be guided by morning cortisol. European Journal of Endocrinology, 173 (5). pp. 633-642. ISSN 0804-4643

Dancer, RCA, Parekh, D, Lax, S et al. (19 more authors) (2015) Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS). Thorax, 70 (7). 617 - 624. ISSN 0040-6376

Nanus, DE, Filer, AD, Yeo, L et al. (8 more authors) (2015) Differential glucocorticoid metabolism in patients with persistent versus resolving inflammatory arthritis. Arthritis Research and Therapy, 171. 121. ISSN 1478-6354

Crowley, RK, Hughes, B, Gray, J et al. (7 more authors) (2014) Longitudinal changes in glucocorticoid metabolism are associated with later development of adverse metabolic phenotype. European Journal of Endocrinology, 171 (4). pp. 433-442. ISSN 0804-4643

Doig, CL, Bashir, J, Zielinska, AE et al. (3 more authors) (2014) TNFα-mediated Hsd11b1 binding of NF-κB p65 is associated with suppression of 11β-HSD1 in muscle. Journal of Endocrinology, 220 (3). 389 - 396. ISSN 0022-0795

Green, AI, Sherlock, M, Stewart, PM et al. (2 more authors) (2014) Extensive experience in the management of macroprolactinomas. Clinical Endocrinology, 81 (1). 85 - 92. ISSN 0300-0664

McNelis, JC, Manolopoulos, KN, Gathercole, LL et al. (4 more authors) (2013) Dehydroepiandrosterone exerts antiglucocorticoid action on human preadipocyte proliferation, differentiation, and glucose uptake. American Journal of Physiology - Endocrinology and Metabolism, 305 (9). E1134 - E1144. ISSN 0193-1849

Lavery, GG, Idkowiak, J, Sherlock, M et al. (12 more authors) (2013) Novel H6PDH mutations in two girls with premature adrenarche: 'apparent' and 'true' CRD can be differentiated by urinary steroid profiling. European Journal of Endocrinology, 168 (2). K19 - K26. ISSN 0804-4643

Hardy, RS, Hülso, C, Liu, Y et al. (9 more authors) (2013) Characterisation of fibroblast-like synoviocytes from a murine model of joint inflammation. Arthritis Research and Therapy, 15 (1). ARTN R24. ISSN 1478-6354

Hardy, R, Juarez, M, Naylor, A et al. (7 more authors) (2012) Synovial DKK1 expression is regulated by local glucocorticoid metabolism in inflammatory arthritis. Arthritis Research and Therapy, 14 (5). ARTN R226. ISSN 1478-6354

Abrahams, L, Semjonous, NM, Guest, P et al. (4 more authors) (2012) Biomarkers of hypothalamic-pituitary-adrenal axis activity in mice lacking 11β-HSD1 and H6PDH. Journal of Endocrinology, 214 (3). 367 - 372. ISSN 0022-0795

Ahasan, MM, Hardy, R, Jones, C et al. (16 more authors) (2012) Inflammatory regulation of glucocorticoid metabolism in mesenchymal stromal cells. Arthritis and Rheumatism, 64 (7). 2404 - 2413. ISSN 0004-3591

Ahmed, A, Rabbitt, E, Brady, T et al. (10 more authors) (2012) A switch in hepatic cortisol metabolism across the spectrum of non alcoholic fatty liver disease. PLoS ONE, 7 (2). ARTN e29531. ISSN 1932-6203

Stewart, PM, Bryan, S, Dukes, P et al. (3 more authors) (2012) What happens to clinical training fellows? A retrospective study of the 20 years outcome of a Medical Research Council UK cohort. BMJ Open, 2 (4). ARTN e001792. ISSN 2044-6055

Tiganescu, A orcid.org/0000-0003-3688-2204, Walker, EA, Hardy, RS et al. (2 more authors) (2011) Localization, age- and site-dependent expression, and regulation of 11β-hydroxysteroid dehydrogenase type 1 in skin. Journal of Investigative Dermatology, 131 (1). pp. 30-36. ISSN 0022-202X

Rahman, TJ, Walker, EA, Mayosi, BM et al. (6 more authors) (2011) Genotype at the P554L variant of the hexose-6 phosphate dehydrogenase gene is associated with carotid intima-medial thickness. PLoS ONE, 6 (8). ARTN e23248. ISSN 1932-6203

Gathercole, LL, Morgan, SA, Bujalska, IJ et al. (3 more authors) (2011) Regulation of lipogenesis by glucocorticoids and insulin in human adipose tissue. PLoS ONE, 6 (10). e26223. ISSN 1932-6203

Gathercole, LL, Morgan, SA, Bujalska, IJ et al. (2 more authors) (2011) Short-and long-term glucocorticoid treatment enhances insulin signalling in human subcutaneous adipose tissue. Nutrition and Diabetes, 1 (1). e3. ISSN 2044-4052

Sinclair, AJ, Burdon, MA, Nightingale, PG et al. (10 more authors) (2010) Low energy diet and intracranial pressure in women with idiopathic intracranial hypertension: prospective cohort study. BMJ (Online), 341 (7764). ARTN c2701. 138 - 138. ISSN 0959-8138

Kaur, K, Hardy, R, Ahasan, MM et al. (10 more authors) (2010) Synergistic induction of local glucocorticoid generation by inflammatory cytokines and glucocorticoids: implications for inflammation associated bone loss. Annals of the Rheumatic Diseases, 69 (6). 1185 - 1190. ISSN 0003-4967

Morgan, SA, Sherlock, M, Gathercole, LL et al. (12 more authors) (2009) 11β-hydroxysteroid dehydrogenase type 1 regulates glucocorticoid- induced insulin resistance in skeletal muscle. Diabetes, 58 (11). 2506 - 2515. ISSN 0012-1797

Stewart, PM and Tomlinson, JW (2009) Selective inhibitors of 11 β-hydroxysteroid dehydrogenase type 1 for patients with metabolic syndrome: is the target liver, fat, or both? Diabetes, 58 (1). 14 - 15. ISSN 0012-1797

Tomlinson, JW, Finney, J, Gay, C et al. (3 more authors) (2008) Impaired glucose tolerance and insulin resistance are associated with increased adipose 11beta-hydroxysteroid dehydrogenase type 1 expression and elevated hepatic 5alpha-reductase activity. Diabetes, 57 (10). 2652 - 2660. ISSN 0012-1797

Bujalska, IJ, Gathercole, LL, Tomlinson, JW et al. (5 more authors) (2008) A novel selective 11β-hydroxysteroid dehydrogenase type 1 inhibitor prevents human adipogenesis. Journal of Endocrinology, 197 (2). 297 - 307. ISSN 0022-0795

Hardy, RS, Rabbitt, EH, Filer, A et al. (7 more authors) (2008) Local and systemic glucocorticoid metabolism in inflammatory arthritis. Annals of the Rheumatic Diseases, 67 (9). 1204 - 1210. ISSN 0003-4967

Bevan, JS, Newell-Price, J, Wass, JAH et al. (8 more authors) (2008) Home administration of lanreotide Autogel (R) by patients with acromegaly, or their partners, is safe and effective. Clinical Endocrinology, 68 (3). 343 - 349. ISSN 0300-0664

Bujalska, IJ, Durrani, OM, Abbott, J et al. (8 more authors) (2007) Characterisation of 11β-hydroxysteroid dehydrogenase 1 in human orbital adipose tissue: a comparison with subcutaneous and omental fat. Journal of Endocrinology, 192 (2). 279 - 288. ISSN 0022-0795

Hardy, RS, Filer, A, Cooper, MS et al. (7 more authors) (2006) Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation. Arthritis Research and Therapy, 8 (4). ARTN R108. ISSN 1478-6354

English, MA, Hughes, SV, Kane, KF et al. (3 more authors) (2000) Oestrogen inactivation in the colon: analysis of the expression and regulation of 17β-hydroxysteroid dehydrogenase isozymes in normal colon and colonic cancer. British Journal of Cancer, 83 (4). 550 - 558. ISSN 0007-0920

Proceedings Paper

Tiganescu, A orcid.org/0000-0003-3688-2204, Farraj, LA, Carr, IM orcid.org/0000-0001-9544-1068 et al. (6 more authors) (2016) 11 beta-hydroxysteroid dehydrogenase type 1 mediates anti-inflammatory, pro-inflammatory and inflammation-independent effects in primary human dermal fibroblasts. In: British Journal of Dermatology. British Skin Foundation, Skin Deep - 20 Years of Research, 20th Anniversary Conference, 13 Oct 2016, London, United Kingdom. Wiley , p. 64.