Items where authors include "Stead, LF"

Article

Barry, A, Samuel, SF, Hosni, I et al. (14 more authors) (2023) Investigating the effects of arginine methylation inhibitors on microdissected brain tumour biopsies maintained in a miniaturised perfusion system. Lab on a Chip, 23 (11). pp. 2664-2682. ISSN 1473-0197

Ajaib, S, Lodha, D, Pollock, S et al. (14 more authors) (2023) GBMdeconvoluteR accurately infers proportions of neoplastic and immune cell populations from bulk glioblastoma transcriptomics data. Neuro-Oncology. ISSN 1522-8517

Barrow, R, Wilkinson, JN, He, Y et al. (4 more authors) (2022) SpheroidAnalyseR—an online platform for analyzing data from 3D spheroids or organoids grown in 96-well plates. Journal of Biological Methods, 9 (4). e163. ISSN 2326-9901

Varn, FS, Johnson, KC, Martinek, J et al. (47 more authors) (2022) Glioma progression is shaped by genetic evolution and microenvironment interactions. Cell, 185 (12). pp. 2184-2199. ISSN 0092-8674

Tanner, G orcid.org/0000-0001-9706-3590, Westhead, DR orcid.org/0000-0002-0519-3820, Droop, A et al. (1 more author) (2021) Benchmarking pipelines for subclonal deconvolution of bulk tumour sequencing data. Nature Communications, 12 (1). 6396. ISSN 2041-1723

Golebiewska, A, Hau, AC, Oudin, A et al. (38 more authors) (2020) Patient-derived organoids and orthotopic xenografts of primary and recurrent gliomas represent relevant patient avatars for precision oncology. Acta Neuropathologica, 140. pp. 919-949. ISSN 0001-6322

Al Amri, WS, Baxter, DE, Hanby, AM orcid.org/0000-0001-7966-1570 et al. (4 more authors) (2020) Identification of candidate mediators of chemoresponse in breast cancer through therapy-driven selection of somatic variants. Breast Cancer Research and Treatment, 183 (3). pp. 607-616. ISSN 0167-6806

Struve, N, Binder, ZA, Stead, LF orcid.org/0000-0002-9550-4150 et al. (19 more authors) (2020) EGFRvIII upregulates DNA mismatch repair resulting in increased temozolomide sensitivity of MGMT promoter methylated glioblastoma. Oncogene, 39 (15). pp. 3041-3055. ISSN 0950-9232

Al Amri, WS, Allinson, LM, Baxter, DE orcid.org/0000-0001-8830-6802 et al. (7 more authors) (2020) Genomic and expression analyses define MUC17 and PCNX1 as predictors of chemotherapy response in breast cancer. Molecular Cancer Therapeutics, 19 (3). pp. 945-955. ISSN 1535-7163

Barthel, FP, Johnson, KC, Varn, FS et al. (86 more authors) (2019) Longitudinal Molecular Trajectories of Diffuse Glioma in Adults. Nature, 576. pp. 112-120. ISSN 0028-0836

da Silva, B, Irving, BK orcid.org/0000-0002-7963-5038, Polson, ES orcid.org/0000-0003-1250-7338 et al. (13 more authors) (2019) Chemically induced neurite-like outgrowth reveals a multicellular network function in patient-derived glioblastoma cells. Journal of Cell Science, 132 (19). jcs228452. ISSN 0021-9533

Tanner, G, Westhead, DR orcid.org/0000-0002-0519-3820, Droop, A orcid.org/0000-0001-7695-7480 et al. (1 more author) (2019) Simulation of heterogeneous tumour genomes with HeteroGenesis and in silico whole exome sequencing. Bioinformatics, 35 (16). pp. 2850-2852. ISSN 1367-4803

Stead, LF orcid.org/0000-0002-9550-4150 and Verhaak, RGW (2019) Doomed from the TERT? A Two-Stage Model of Tumorigenesis in IDH-Wild-Type Glioblastoma. Cancer Cell, 35 (4). pp. 542-544. ISSN 1535-6108

Droop, A orcid.org/0000-0001-7695-7480, Bruns, A orcid.org/0000-0002-6970-4036, Tanner, G et al. (12 more authors) (2018) How to analyse the spatiotemporal tumour samples needed to investigate cancer evolution: A case study using paired primary and recurrent glioblastoma. International Journal of Cancer, 142 (8). pp. 1620-1626. ISSN 0020-7136

Samson, A orcid.org/0000-0002-3081-7850, Scott, KJ orcid.org/0000-0002-5790-9579, Taggart, D et al. (36 more authors) (2018) Intravenous delivery of oncolytic reovirus to brain tumor patients immunologically primes for subsequent checkpoint blockade. Science Translational Medicine, 10 (422). eaam7577. ISSN 1946-6234

Hurst, CD orcid.org/0000-0001-7719-1325, Alder, O orcid.org/0000-0002-7975-9727, Platt, FM et al. (15 more authors) (2017) Genomic Subtypes of Non-Invasive Bladder Cancer with Distinct Metabolic Profile and Female Gender Bias in KDM6A Mutation Frequency. Cancer Cell, 32 (5). pp. 701-715. ISSN 1535-6108

Humphries, MP orcid.org/0000-0003-1306-7012, Rajan, SS, Droop, A orcid.org/0000-0001-7695-7480 et al. (29 more authors) (2017) A Case Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic and Tractable Biomarkers in Male Breast Cancer. Clinical Cancer Research, 23 (10). pp. 2575-2583. ISSN 1078-0432

Webster, PJ, Littlejohns, AT, Gaunt, HJ et al. (17 more authors) (2017) Upregulated WEE1 protects endothelial cells of colorectal cancer liver metastases. Oncotarget, 8 (26). pp. 42288-42299. ISSN 1949-2553

King, HO, Brend, T, Payne, HL et al. (8 more authors) (2017) RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells. Stem Cell Reports, 8 (1). pp. 125-139.

Town, J, Pais, H, Harrison, S et al. (5 more authors) (2016) Exploring the surfaceome of Ewing sarcoma identifies a new and unique therapeutic target. Proceedings of the National Academy of Sciences, 113 (13).

Conway, C, Graham, JL, Chengot, P et al. (6 more authors) (2015) Elucidating drivers of oral epithelial dysplasia formation and malignant transformation to cancer using RNAseq. Oncotarget, 6 (37). pp. 40186-40201.

Smith, L, Baxter, EW, Chambers, PA et al. (8 more authors) (2015) Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis. PLoS ONE, 10 (10). e0139698. ISSN 1932-6203

Stead, LF, Thygesen, H, Westhead, DR et al. (1 more author) (2015) Using common variants to indicate cancer genes. International Journal of Cancer, 136 (1). 241 - 245. ISSN 0020-7136

Stead, LF, Egan, P, Devery, A et al. (8 more authors) (2013) An integrated inspection of the somatic mutations in a lung squamous cell carcinoma using next-generation sequencing. PLoS One, 8 (11). ARTN e78823. ISSN 1932-6203

Conference or Workshop Item

Struve, N, Binder, ZA, Stead, LF orcid.org/0000-0002-9550-4150 et al. (18 more authors) (2019) CBMT-16: EGFRvIII Expression Confers Chemosensitivity by Increasing DNA Mismatch Repair Protein Expression and Replication Stress. In: 24th Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology, 22-24 Nov 2019, Phoenix, Arizona, USA.

Barthel, F, Johnson, KC, Frederick Jr, V et al. (10 more authors) (2019) GENE-28. Longitudinal Molecular Trajectories of Diffuse Glioma in Adults. In: 24th Annual Scientific Meeting and Education Day of the Society for Neuro-Oncology, 20-24 Nov 2019, Phoenix, Arizona, USA.

Bruns, A-F, Rippaus, N, Droop, A et al. (8 more authors) (2019) Chromatin remodelling to facilitate treatment resistance in glioblastoma. In: British Neuro-Oncology Society Annual Meeting 2019 (BNOS 2019), 03-05 Jul 2019, London, UK.

Rippaus, N, Manning, J, Droop, A et al. (9 more authors) (2019) OS9.5 Evidence that adult glioblastoma adapts to standard therapy though chromatin remodeling. In: 14th Meeting of the European Association of Neuro-Oncology, 19-22 Sep 2019, Lyon, France.

Proceedings Paper

Close, HJ, Wurdak, H, Short, SC et al. (4 more authors) (2014) Natural killer cell recognition of glioblastoma. In: Immunology. British Society for Immunology Annual Congress 2014, 01-04 Dec 2014, Brighton, UK. Wiley , 138 - 138.