Items where authors include "Speirs, V"

Article

Sunderland, A, Williams, J, Andreou, T et al. (8 more authors) (2023) Biglycan and reduced glycolysis are associated with breast cancer cell dormancy in the brain. Frontiers in Oncology, 13. 1191980. ISSN 2234-943X

Liu, P, Roberts, S, Shoemaker, JT et al. (3 more authors) (2023) Validation of a 3D perfused cell culture platform as a tool for humanised preclinical drug testing in breast cancer using established cell lines and patient-derived tissues. PLOS ONE, 18 (3). e0283044. ISSN 1932-6203

Volpato, M orcid.org/0000-0002-7851-4533, Cummings, M, Shaaban, AM et al. (9 more authors) (2020) Downregulation of 15-hydroxyprostaglandin dehydrogenase during acquired tamoxifen resistance and association with poor prognosis in ERα-positive breast cancer. Exploration of Targeted Anti-tumor Therapy, 2020 (1). pp. 355-371. ISSN 2692-3114

Kather, JN, Heij, LR, Grabsch, H orcid.org/0000-0001-9520-6228 et al. (25 more authors) (2020) Pan-cancer image-based detection of clinically actionable genetic alterations. Nature Cancer, 1 (8). pp. 789-799. ISSN 2662-1347

Westbrook, JA, Wood, SL, Cairns, DA orcid.org/0000-0002-2338-0179 et al. (14 more authors) (2019) Identification and validation of DOCK4 as a potential biomarker for risk of bone metastasis development in patients with early breast cancer. The Journal of pathology, 247 (3). pp. 381-391. ISSN 0022-3417

Coulson-Gilmer, C, Humphries, MP, Sundara Rajan, S et al. (14 more authors) (2018) Stanniocalcin 2 expression is associated with a favourable outcome in male breast cancer. The Journal of Pathology: Clinical Research, 4 (4). pp. 241-249. ISSN 2056-4538

Lees, T, Cullinane, A, Condon, A et al. (3 more authors) (2018) Characterising the adipose-inflammatory microenvironment in male breast cancer. Endocrine-Related Cancer, 25 (7). pp. 773-781. ISSN 1351-0088

Pollard, J, Burns, PA, Hughes, TA orcid.org/0000-0003-1169-3386 et al. (7 more authors) (2018) Differential Expression of MicroRNAs in Breast Cancers from Four Different Ethnicities. Pathobiology, 85 (4). pp. 220-226. ISSN 1015-2008

Cheang, MCU, Bliss, JM, Viale, G et al. (12 more authors) (2018) Evaluation of applying IHC4 as a prognostic model in the translational study of Intergroup Exemestane Study (IES): PathIES. Breast Cancer Research and Treatment, 168 (1). pp. 169-178. ISSN 0167-6806

Alhodhodi, A, Alkharobi, H, Humphries, M et al. (5 more authors) (2017) Oestrogen receptor β (ERβ) regulates osteogenic differentiation of human dental pulp cells. Journal of Steroid Biochemistry and Molecular Biology, 174. pp. 296-302. ISSN 0960-0760

Wilson, H and Speirs, V orcid.org/0000-0002-0602-4666 (2017) Attitudes of female staff and students from two United Kingdom Medical Schools towards donating normal healthy breast tissue and blood samples for biomedical research. Breast Cancer Research and Treatment, 166 (2). pp. 651-652. ISSN 0167-6806

Baldacchino, S, Wastall, LM, Saliba, C et al. (6 more authors) (2017) CIP2A expression predicts recurrences of tamoxifen-treated breast cancer. Tumour Biology, 39 (10). ISSN 1010-4283

Di Benedetto, A, Ercolani, C, Mottolese, M et al. (13 more authors) (2017) Analysis of the ATR-Chk1 and ATM-Chk2 pathways in male breast cancer revealed the prognostic significance of ATR expression. Scientific Reports, 7. 8078. ISSN 2045-2322

Roberts, S and Speirs, V orcid.org/0000-0002-0602-4666 (2017) Advances in the development of improved animal-free models for use in breast cancer biomedical research. Biophysical Reviews, 9 (4). pp. 321-327. ISSN 1867-2450

Di Benedetto, A, Mottolese, M, Sperati, F et al. (12 more authors) (2017) Association between AXL, Hippo transducers and survival outcomes in male breast cancer. Journal of Cellular Physiology, 232 (8). pp. 2246-2252. ISSN 0021-9541

Kamal, M, Holliday, DL, Morrison, EE et al. (3 more authors) (2017) Loss of CSMD1 expression disrupts mammary duct formation while enhancing proliferation, migration and invasion. Oncology Reports, 38 (1). pp. 283-292. ISSN 1021-335X

Humphries, MP orcid.org/0000-0003-1306-7012, Rajan, SS, Droop, A orcid.org/0000-0001-7695-7480 et al. (29 more authors) (2017) A Case Matched Gender Comparison Transcriptomic Screen Identifies eIF4E and eIF5 as Potential Prognostic and Tractable Biomarkers in Male Breast Cancer. Clinical Cancer Research, 23 (10). pp. 2575-2583. ISSN 1078-0432

Holen, I, Speirs, V orcid.org/0000-0002-0602-4666, Morrissey, B orcid.org/0000-0003-2369-276X et al. (1 more author) (2017) In vivo models in breast cancer research: progress, challenges and future directions. Disease Models and Mechanisms, 10 (4). pp. 359-371. ISSN 1754-8403

Humphries, MP orcid.org/0000-0003-1306-7012, Sundara Rajan, S, Honarpisheh, H et al. (18 more authors) (2017) Characterisation of male breast cancer: a descriptive biomarker study from a large patient series. Scientific Reports, 7. 45293. ISSN 2045-2322

Morrissey, B, Blyth, K, Carter, P et al. (4 more authors) (2017) The Sharing Experimental Animal Resources, Coordinating Holdings (SEARCH) Framework: Encouraging Reduction, Replacement, and Refinement in Animal Research. PLoS Biology, 15 (1). e2000719. ISSN 1544-9173

Di Benedetto, A, Mottolese, M, Sperati, F et al. (12 more authors) (2016) HMG-CoAR expression in male breast cancer: relationship with hormone receptors, Hippo transducers and survival outcomes. Scientific Reports, 6. 35121. ISSN 2045-2322

Speirs, V orcid.org/0000-0002-0602-4666, Morrissey, B, Holen, I et al. (4 more authors) (2016) SEARCHBreast: An online resource designed to increase the efficiency of using materials derived from breast cancer studies in animals. Journal of Pathology, 240 (1). p. 120. ISSN 0022-3417

Carter, P, Blyth, K, Holen, I et al. (4 more authors) (2016) The SEARCHBreast Portal: A Virtual Bioresource to Facilitate the Sharing of Surplus Animal Materials Derived from Breast Cancer Studies. Open Journal of Bioresources, 3 (1). ISSN 2056-5542

Di Benedetto, A, Mottolese, M, Sperati, F et al. (12 more authors) (2016) The Hippo transducers TAZ/YAP and their target CTGF in male breast cancer. Oncotarget, 7 (28). pp. 43188-43198. ISSN 1949-2553

Morrissey, B, Holen, I, Chelala, C et al. (4 more authors) (2016) Introducing SEARCHBreast: a virtual resource to facilitate sharing of surplus animal material developed for breast cancer research. npj Breast Cancer, 2 (1). 16020. ISSN 2374-4677

Roberts, GC orcid.org/0000-0003-4687-6940, Morris, PG, Moss, MA et al. (6 more authors) (2016) An Evaluation of Matrix-Containing and Humanised Matrix-Free 3-Dimensional Cell Culture Systems for Studying Breast Cancer. PLoS ONE, 11 (6). e0157004. ISSN 1932-6203

Hawsawi, Y, Humphries, MP orcid.org/0000-0003-1306-7012, Wright, A et al. (8 more authors) (2016) Deregulation of IGF-binding proteins -2 and -5 contributes to the development of endocrine resistant breast cancer in vitro. Oncotarget, 7 (22). pp. 32129-32143. ISSN 1949-2553

Morrissey, B, Blyth, K, Carter, P et al. (4 more authors) (2016) SEARCHBreast: a new online resource to make surplus material from in vivo models of breast cancer visible and accessible to researchers. Breast Cancer Research, 18. 59. ISSN 1465-5411

Blyth, K, Carter, P, Morrissey, B et al. (4 more authors) (2016) SEARCHBreast: a new resource to locate and share surplus archival material from breast cancer animal models to help address the 3Rs. Breast Cancer Research and Treatment, 156 (3). pp. 447-452. ISSN 0167-6806

Westbrook, JA, Cairns, DA orcid.org/0000-0002-2338-0179, Peng, J et al. (10 more authors) (2016) CAPG and GIPC1: Breast Cancer Biomarkers for Bone Metastasis Development and Treatment. JNCI: Journal of the National Cancer Institute, 108 (4). ISSN 0027-8874

Patel, F, Achuthan, R, Hyklova, L et al. (2 more authors) (2016) Management of breast cancer in an Asian man with post-traumatic stress disorder: a case report. Journal of Medical Case Reports, 10 (77). ISSN 1752-1947

Avgustinova, A, Iravani, M, Robertson, D et al. (8 more authors) (2016) Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness. Nature Communications, 7. 10305. ISSN 2041-1723

Booth, ME, Nash, CE, Roberts, NP et al. (4 more authors) (2015) 3-D tissue modelling and virtual pathology as new approaches to study ductal carcinoma in situ. Alternatives to Laboratory Animals, 43 (6). pp. 377-383. ISSN 0261-1929

Romanska, HM, Potemski, P, Krakowska, M et al. (8 more authors) (2015) Lack of CD151/integrin alpha 3 beta 1 complex is predictive of poor outcome in node-negative lobular breast carcinoma: opposing roles of CD151 in invasive lobular and ductal breast cancers. British Journal of Cancer, 113 (9). pp. 1350-1357. ISSN 0007-0920

Di Lauro, L, Barba, M, Pizzuti, L et al. (8 more authors) (2015) Androgen receptor and antiandrogen therapy in male breast cancer. Cancer Letters, 368 (1). pp. 20-25. ISSN 0304-3835

Smith, L, Baxter, EW, Chambers, PA et al. (8 more authors) (2015) Down-Regulation of miR-92 in Breast Epithelial Cells and in Normal but Not Tumour Fibroblasts Contributes to Breast Carcinogenesis. PLoS ONE, 10 (10). e0139698. ISSN 1932-6203

Speirs, V (2015) Animal research: Share surplus animal tissue. Nature, 522 (7555). p. 156. ISSN 0028-0836

Humphries, MP, Jordan, VC and Speirs, V (2015) Obesity and male breast cancer: Provocative parallels? BMC Medicine, 13 (1). 134. ISSN 1741-7015

Booth, M, Treanor, D, Roberts, N et al. (3 more authors) (2015) Three dimensional reconstruction of ductal carcinoma in situ using virtual slides. Histopathology, 66 (7). 966 - 973. ISSN 0309-0167

Downey, CL, Simpkins, SA, Holliday, DL et al. (5 more authors) (2015) Reponse to: comment on, 'Tumour-stroma ratio (TSR) in oestrogen-positive breast cancer patients'. British Journal of Cancer, 112 (11). 1833 - 1834. ISSN 0007-0920

Speirs, V, Viale, G, Mousa, K et al. (14 more authors) (2015) Prognostic and predictive value of ERβ1 and ERβ2 in the Intergroup Exemestane Study (IES) - first results from PathIES. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. ISSN 0923-7534

Di Lauro, L, Pizzuti, L, Barba, M et al. (10 more authors) (2015) Role of gonadotropin-releasing hormone analogues in metastatic male breast cancer: Results from a pooled analysis. Journal of Hematology and Oncology, 8 (1). 53. ISSN 1756-8722

Rea, D, Francis, A, Hanby, AM et al. (9 more authors) (2015) Inflammatory breast cancer: Time to standardise diagnosis assessment and management, and for the joining of forces to facilitate effective research. British Journal of Cancer, 112 (9). 1613 - 1615. ISSN 0007-0920

Nash, CE, Mavria, G, Baxter, EW et al. (7 more authors) (2015) Development and characterisation of a 3D multi-cellular in vitro model of normal human breast: a tool for cancer initiation studies. Oncotarget.

Langlands, FE, Dodwell, D, Hanby, AM et al. (6 more authors) (2014) PSMD9 expression predicts radiotherapy response in breast cancer. Molecular Cancer, 13. 73. ISSN 1476-4598

Hawsawi, Y, El-Gendy, R, Twelves, C et al. (2 more authors) (2013) Insulin-like growth factor - Oestradiol crosstalk and mammary gland tumourigenesis. BBA - Reviews on Cancer, 1836 (2). 345 - 353. ISSN 0304-419X

Verghese, ET, Drury, R, Green, CA et al. (10 more authors) (2013) MiR-26b is down-regulated in carcinoma-associated fibroblasts from ER-positive breast cancers leading to enhanced cell migration and invasion. The Journal of Pathology, 231 (3). pp. 388-399. ISSN 0022-3417

Shaaban, AM, Green, AR, Karthik, S et al. (9 more authors) (2008) Nuclear and Cytoplasmic Expression of ER 1, ER 2, and ER 5 Identifies Distinct Prognostic Outcome for Breast Cancer Patients. Clinical Cancer Research, 14 (16). pp. 5228-5235. ISSN 1078-0432

Speirs, V (2003) Breast Cancer Research(Editorship). Breast Cancer Research, 5 (160-161). ISSN 1465-5411

Book Section

Speirs, V orcid.org/0000-0002-0602-4666, Humphries, MP and Shaaban, A (2018) Male Breast Cancer. In: van Krieken, JHJM, (ed.) Encyclopedia of Pathology. Encyclopedia of Pathology . Springer , Cham, Switzerland . ISBN 978-3-319-28845-1

Conference or Workshop Item

Egnuni, T, Speirs, V orcid.org/0000-0002-0602-4666, Chakrabarty, A et al. (3 more authors) (2018) Rho GTPase signaling and role of the Rac1 exchange factor DOCK4 in GBM invasion and vascular growth. In: BNOS 2017, 21-23 Jun 2017, Edinburgh.

Egnuni, T, Speirs, V orcid.org/0000-0002-0602-4666, Chakrabarty, A et al. (4 more authors) (2017) Rho GTPase signalling in cancer cell invasion and angiogenesis in brain tumours. In: BNOS 2016, 29 Jun 2016, Leeds.

Proceedings Paper

Leif, F, Pfänder, P, Murtuza Baker, S et al. (8 more authors) (2019) Nuclear receptor profiling predicts chemical disruptors as risk factors for developing breast cancer. In: Endocrine Abstracts (2019). Society for Endocrinology BES 2019, 11-13 Nov 2019, Brighton, UK. Society for Endicronology .

Elmoursi, M, Forbes, K orcid.org/0000-0002-3745-1337, Stahlschmidt, J et al. (2 more authors) (2017) Placental autophagy regulates trophoblast survival in placental dysfunction during pregnancy complications. In: Placenta. International Federation of Placenta Associations Meeting, 30 Aug - 02 Sep 2017, Manchester, UK. Elsevier , p. 323.

Humphries, MP, Suleman, C, Hanby, A et al. (1 more author) (2016) A comparative study of male versus female breast cancer identifies overexpression of eiF signalling pathways in male breast cancer providing opportunities for a therapeutic window. In: Breast Cancer Research and Treatment. UK Breast Cancer Research Symposium 2016, 22-23 Jul 2016, London, UK. Springer Verlag , p. 188.

Morrissey, B orcid.org/0000-0003-2369-276X, Blyth, K, Carter, P et al. (4 more authors) (2016) SEARCHBreast; making surplus material from in vivo models of breast cancer available for research. In: European Journal of Cancer. 24th Biennial Congress of the European Association for Cancer Research, 09-12 Jul 2016, Manchester, United Kingdom. Elsevier , S198-S198.

Morrissey, B, Blyth, K, Carter, P et al. (4 more authors) (2015) SEARCHBreast Workshop Proceedings: 3D modelling of breast cancer. In: ATLA Alternatives to Laboratory Animals. SEARCHBreast Workshop on 3D Modelling of Breast Cancer, 21 May 2015, London, UK. FRAME , pp. 367-375.

ElMoursi, M, Simpson, NAB orcid.org/0000-0002-0758-7583, Stahlschmidt, J et al. (2 more authors) (2015) Digital pathology analysis reveals enhanced autophagy expression in pre-eclamptic placenta. In: BJOG: An International Journal of Obstetrics and Gynaecology. Blair Bell Research Society, 21-23 Jan 2015. Wiley , E2-E2.

ElMoursi, M, Speirs, V orcid.org/0000-0002-0602-4666, Stahlschmidt, J et al. (2 more authors) (2015) Trophoblast apoptotic burden in fetal growth restriction (FGR) placenta: an image analysis study. In: BJOG: An International Journal of Obstetrics and Gynaecology. Blair Bell Research Society, 21-23 Jan 2015. Wiley , E1-E2.

Grant, G, Gahlaut, R, Abraham, S et al. (9 more authors) (2015) The role of dock4 in cancer cell invasion and angiogenesis in breast cancer brain metastates. In: Neuro-Oncology. Meeting of the British-Neuro-Oncology-Society, 01-03 Jul 2015, Nottingham, UK. Oxford University Press , p. 10.

Hawsawi, YM, Jove, M, Humphries, M et al. (5 more authors) (2015) Role of Insulin like Growth Factor Binding Proteins and Tamoxifen Resistance in Breast Cancer Epithelial Cells. In: Journal of Pathology. Dublin Pathology 2015. 8th Joint Meeting of the British Division of the International Academy of Pathology and the Pathological Society of Great Britain & Ireland, 23-25 Jun 2015, Dublin, Ireland. Wiley , S19-S19.