Items where authors include "Ponnambalam, S"

Article

Divan, A, Alzahrani, A, Shaik, F et al. (4 more authors) (2023) A research‐led flexible cell biology practical for biological sciences undergraduate and postgraduate degree courses. Biochemistry and Molecular Biology Education, 51 (4). pp. 394-401. ISSN 1470-8175

Jade, D, Alzahrani, A, Critchley, W orcid.org/0000-0002-2707-4080 et al. (2 more authors) (2023) Identification of FDA-approved drugs against SARS-CoV-2 RNA-dependent RNA polymerase (RdRp) through computational virtual screening. Structural Chemistry, 34. pp. 1005-1019. ISSN 1040-0400

Critchley, WR orcid.org/0000-0002-2707-4080, Smith, GA, Zachary, IC et al. (2 more authors) (2023) The E2 ubiquitin-conjugating enzymes UBE2D1 and UBE2D2 regulate VEGFR2 dynamics and endothelial function. Journal of Cell Science, 136 (10). jcs260657. ISSN 0021-9533

Alsayejh, B, Kietsiriroje, N, Almutairi, M et al. (4 more authors) (2022) Plasmin Inhibitor in Health and Diabetes: Role of the Protein as a Therapeutic Target. TH open : companion journal to thrombosis and haemostasis, 6 (4). e396-e407. ISSN 2512-9465

Pechlivani, N orcid.org/0000-0001-5041-5763, Kearney, KJ orcid.org/0000-0002-0387-6812, Tiede, C et al. (7 more authors) (2022) Affinity purification of fibrinogen using an Affimer column. Biochimica et Biophysica Acta (BBA) - General Subjects, 1866 (5). 130115. ISSN 0304-4165

Critchley, WR orcid.org/0000-0002-2707-4080, Fearnley, GWF, Abdul-Zani, I et al. (5 more authors) (2022) Monitoring VEGF-Stimulated Calcium Ion Flux in Endothelial Cells. Methods in Molecular Biology, 2475. pp. 113-124. ISSN 1064-3745

Dai, Z-T, Xiang, Y, Zhang, X-Y et al. (7 more authors) (2021) Regulation of follistatin-like 3 expression by miR-486-5p modulates gastric cancer cell proliferation, migration and tumor progression. Aging, 13 (16). pp. 20302-20318. ISSN 1945-4589

Dai, Z-T, Xiang, Y, Wang, Y et al. (7 more authors) (2021) Prognostic value of members of NFAT family for pan-cancer and a prediction model based on NFAT2 in bladder cancer. Aging, 13. ISSN 1945-4589

Shaik, F, Cuthbert, GA, Homer-Vanniasinkam, S et al. (3 more authors) (2020) Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy. Biomolecules, 10 (12). 1673. pp. 1-25. ISSN 2218-273X

Cuthbert, GA, Shaik, F, Harrison, MA orcid.org/0000-0002-7826-7472 et al. (2 more authors) (2020) Scavenger Receptors as Biomarkers and Therapeutic Targets in Cardiovascular Disease. Cells, 9 (11). p. 2453. ISSN 2073-4409

King, RJ, Schuett, K, Tiede, C orcid.org/0000-0003-0280-4005 et al. (10 more authors) (2020) Fibrinogen interaction with complement C3: a potential therapeutic target to reduce thrombosis risk. Haematologica. ISSN 0390-6078

Fearnley, GW, Latham, AM, Hollstein, M et al. (2 more authors) (2020) ATF-2 and Tpl2 regulation of endothelial cell cycle progression and apoptosis. Cellular Signalling, 66. 109481. ISSN 0898-6568

Fearnley, GW, Abdul-Zani, I, Latham, AM et al. (5 more authors) (2019) Tpl2 is required for VEGF-A-stimulated signal transduction and endothelial cell function. Biology Open, 8 (5). bio034215. ISSN 2046-6390

López-García, M orcid.org/0000-0003-3833-8595, Nowicka, M, Bendtsen, C et al. (3 more authors) (2018) Quantifying the phosphorylation timescales of receptor–ligand complexes: a Markovian matrix-analytic approach. Open Biology, 8 (9). 180126. ISSN 2046-2441

Critchley, WR, Pellet-Many, C, Ringham-Terry, B et al. (3 more authors) (2018) Receptor Tyrosine Kinase Ubiquitination and De-Ubiquitination in Signal Transduction and Receptor Trafficking. Cells, 7 (3). 22. ISSN 2073-4409

Bridgewood, C, Fearnley, GW, Berekmeri, A et al. (6 more authors) (2018) IL-36 gamma Is a Strong Inducer of IL-23 in Psoriatic Cells and Activates Angiogenesis. Frontiers in Immunology, 9. ARTN 200. ISSN 1664-3224

Smith, GA, Fearnley, G, Abdul Zani, I et al. (4 more authors) (2017) Ubiquitination of basal VEGFR2 regulates signal transduction and endothelial function. Biology Open, 6 (10). pp. 1404-1415. ISSN 2046-6390

Tiede, C orcid.org/0000-0003-0280-4005, Bedford, R, Heseltine, SJ et al. (43 more authors) (2017) Affimer proteins are versatile and renewable affinity reagents. eLife, 6. e24903. ISSN 2050-084X

Peng, H, Hao, Y, Mousawi, F orcid.org/0000-0003-2267-2652 et al. (6 more authors) (2016) Purinergic and Store‐Operated Ca²⁺ Signaling Mechanisms in Mesenchymal Stem Cells and Their Roles in ATP‐Induced Stimulation of Cell Migration. Stem Cells, 34 (8). pp. 2102-2114. ISSN 1066-5099

Fearnley, GW, Smith, GA, Abdul Zani, I et al. (9 more authors) (2016) VEGF-A isoforms program differential VEGFR2 signal transduction, trafficking and proteolysis. Biology Open, 2016 (5). pp. 571-583. ISSN 2046-6390

Smith, GA, Howell, G, Phillips, C et al. (3 more authors) (2016) Extracellular and Luminal pH Regulation by Vacuolar H⁺-ATPase Isoform Expression and Targeting to the Plasma Membrane and Endosomes. Journal of Biological Chemistry, 291 (16). pp. 8500-8515. ISSN 0021-9258

Windheim, M, Höning, S, Leppard, KN et al. (4 more authors) (2016) Sorting motifs in the cytoplasmic tail of the immunomodulatory E3/49K protein of species D adenoviruses modulate cell surface expression and ectodomain shedding. Journal of Biological Chemistry, 291 (13). pp. 6796-6812. ISSN 0021-9258

Smith, GA, Fearnley, GW, Zani, IA et al. (4 more authors) (2016) VEGFR2 trafficking, signaling and proteolysis is regulated by the ubiquitin isopeptidase USP8. Traffic, 17 (1). pp. 53-65. ISSN 1398-9219

De Siqueira, J, Abdul Zani, I, Russell, DA et al. (3 more authors) (2015) Clinical and Preclinical Use of LOX-1-Specific Antibodies in Diagnostics and Therapeutics. Journal of Cardiovascular Translational Research, 8 (8). pp. 458-465. ISSN 1937-5387

Yang, Z, Kirton, HM, MacDougall, DA et al. (9 more authors) (2015) The Golgi apparatus is a functionally distinct Ca2+ store regulated by the PKA and Epac branches of the β1-adrenergic signaling pathway. Science Signaling, 8 (398). ra101. ISSN 1945-0877

Smith, GA, Fearnley, GW, Tomlinson, DC et al. (2 more authors) (2015) The cellular response to vascular endothelial growth factors requires co-ordinated signal transduction, trafficking and proteolysis. Bioscience Reports, 35 (5). e00253. ISSN 0144-8463

Fearnley, GW, Wheatcroft, SB and Ponnambalam, S orcid.org/0000-0002-4452-7619 (2015) Detection and Quantification of Vascular Endothelial Growth Factor Receptor Tyrosine Kinases in Primary Human Endothelial Cells. Methods in Molecular Biology, 1332. pp. 49-65. ISSN 1064-3745

Latham, AM, Kankanala, J, Fishwick, CWG et al. (1 more author) (2015) Identification of Receptor Tyrosine Kinase Inhibitors Using Cell Surface Biotinylation and Affinity Isolation. Methods in Molecular Biology, 1332. pp. 121-131. ISSN 1064-3745

Smith, GA, Fearnley, GW, Harrison, MA et al. (3 more authors) (2015) Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease. Journal of Inherited Metabolic Disease, 38 (4). 753 - 763. ISSN 0141-8955

Fearnley, GW, Bruns, AF, Wheatcroft, SB et al. (1 more author) (2015) VEGF-A isoform-specific regulation of calcium ion flux, transcriptional activation and endothelial cell migration. Biology open, 4 (6). 731 - 742.

Zani, IA, Stephen, SL, Mughal, NA et al. (4 more authors) (2015) Scavenger receptor structure and function in health and disease. Cells, 4 (2). 178 - 201. ISSN 2073-4409

Latham, AM, Kankanala, J, Fearnley, GW et al. (6 more authors) (2014) In silico design and biological evaluation of a dual specificity kinase inhibitor targeting cell cycle progression and angiogenesis. PLoS ONE, 9 (11). ARTN e110997. ISSN 1932-6203

Shaw, DJ, Seese, R, Ponnambalam, S et al. (1 more author) (2014) The role of lectin-like oxidised low-density lipoprotein receptor-1 in vascular pathology. Diabetes and Vascular Disease Research, 11 (6). pp. 410-418. ISSN 1479-1641

Cubbon, RM orcid.org/0000-0001-7844-3600, Yuldasheva, NY orcid.org/0000-0001-6213-6358, Viswambharan, H orcid.org/0000-0002-7616-5026 et al. (20 more authors) (2014) Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential. Stem Cells, 32 (10). pp. 2714-2723. ISSN 1066-5099

Fearnley, GW, Odell, AF, Latham, AM et al. (8 more authors) (2014) VEGF-A isoforms differentially regulate ATF-2-dependent VCAM-1 gene expression and endothelial-leukocyte interactions. Molecular Biology of the Cell, 25 (16). 2509 - 2521. ISSN 1059-1524

Jopling, HM, Odell, AF, Pellet-Many, C et al. (6 more authors) (2014) Endosome-to-plasma membrane recycling of VEGFR2 receptor tyrosine kinase regulates endothelial function and blood vessel formation. Cells, 3 (2). 363 - 385. ISSN 2073-4409

Fearnley, GW, Smith, GA, Odell, AF et al. (5 more authors) (2014) Vascular endothelial growth factor A-stimulated signaling from endosomes in primary endothelial cells. Methods in Enzymology, 535. 265 - 292. ISSN 0076-6879

Holloway, ZG, Velayos-Baeza, A, Howell, GJ et al. (4 more authors) (2013) Trafficking of the Menkes copper transporter ATP7A is regulated by clathrin-, AP-2-, AP-1-, and Rab22-dependent steps. Molecular Biology of the Cell, 24 (11). 1735 - 1748. ISSN 1059-1524

Book Section

Saikia, Q, Reeve, H, Alzahrani, A et al. (5 more authors) (2022) VEGFR endocytosis: Implications for angiogenesis. In: Progress in Molecular Biology and Translational Science. Progress in Molecular Biology and Translational Science . Elsevier .

Roper, BWR orcid.org/0000-0002-9897-4254, Al-Sayejh, B, Al-Aufi,, A et al. (7 more authors) (2022) Purification and analysis of circulating lipid particles. In: Methods in Molecular Biology. Methods in Molecular Biology . Springer Nature .