Items where authors include "Philippou, H"

Article

Hardy, LJ, Bohinc, D, Bane, KL et al. (9 more authors) (2023) Glycated albumin modulates the contact system with implications for the kallikrein-kinin and intrinsic coagulation systems. Journal of Thrombosis and Haemostasis, 21 (4). pp. 814-827. ISSN 1538-7933

Heal, SL, Hardy, LJ, Wilson, CL et al. (4 more authors) (2022) Novel interaction of properdin and coagulation factor XI: Crosstalk between complement and coagulation. Research and Practice in Thrombosis and Haemostasis, 6 (4). e12715. ISSN 2475-0379

Foster, H, Wilson, C, Gauer, JS orcid.org/0000-0002-0835-639X et al. (8 more authors) (2022) A Comparative Assessment Study of Known Small-molecule GPVI Modulators. ACS Medicinal Chemistry Letters, 13 (2). pp. 171-181. ISSN 1948-5875

McPherson, HR, Duval, C orcid.org/0000-0002-4870-6542, Baker, SR et al. (10 more authors) (2021) Fibrinogen αC-subregions critically contribute blood clot fibre growth, mechanical stability, and resistance to fibrinolysis. eLife, 10. e68761. ISSN 2050-084X

Bentley, R, Hardy, LJ, Scott, LJ et al. (3 more authors) (2021) Drugs in phase I and II clinical development for the prevention of stroke in patients with atrial fibrillation. Expert Opinion on Investigational Drugs, 30 (10). pp. 1057-1069. ISSN 1354-3784

Duval, C orcid.org/0000-0002-4870-6542, Baranauskas, A, Feller, T et al. (14 more authors) (2021) Elimination of fibrin γ-chain cross-linking by FXIIIa increases pulmonary embolism arising from murine inferior vena cava thrombi. Proceedings of the National Academy of Sciences, 118 (27). e2103226118. ISSN 0027-8424

Kearney, KJ orcid.org/0000-0002-0387-6812, Butler, J, Posada, OM et al. (10 more authors) (2021) Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI. Proceedings of the National Academy of Sciences, 118 (3). e2014810118. ISSN 0027-8424

Shi, Y, Gauer, JS orcid.org/0000-0002-0835-639X, Baker, SR et al. (3 more authors) (2021) Neutrophils can Promote Clotting via FXI and Impact Clot Structure via Neutrophil Extracellular Traps in a Distinctive Manner in vitro. Scientific Reports, 11. 1718. ISSN 2045-2322

Philippou, H (2021) New Rapid and Cost-Effective Tool for Monitoring DOACs. Thrombosis and Haemostasis, 121 (01). 007. ISSN 0340-6245

Foster, H, Wilson, C, Philippou, H et al. (1 more author) (2020) Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis. Journal of Medicinal Chemistry, 63 (21). pp. 12213-12242. ISSN 0022-2623

Gauer, JS orcid.org/0000-0002-0835-639X, Riva, N, Page, EM et al. (4 more authors) (2020) Effect of anticoagulants on fibrin clot structure: A comparison between vitamin K antagonists and factor Xa inhibitors. Research and Practice in Thrombosis and Haemostasis, 4 (8). pp. 1269-1281. ISSN 2475-0379

Anokhin, BA, Dean, WL, Smith, KA orcid.org/0000-0001-5695-7117 et al. (4 more authors) (2020) Proteolytic and nonproteolytic activation mechanisms result in conformationally and functionally different forms of coagulation factor XIII A. The FEBS Journal, 287 (3). pp. 452-464. ISSN 1742-464X

Ghaithi, R, Mori, J, Nagy, Z et al. (7 more authors) (2019) Evaluation of the Total Thrombus-Formation System (T-TAS): application to human and mouse blood analysis. Platelets, 30 (7). pp. 893-900. ISSN 0953-7104

Singh, S, Dodt, J, Volkers, P et al. (6 more authors) (2019) Structure functional insights into calcium binding during the activation of coagulation factor XIII A. Scientific Reports, 9. 11324. ISSN 2045-2322

Philippou, H (2019) Heavy chain of FXII: not an innocent bystander! Blood, 133 (10). pp. 1008-1009. ISSN 0006-4971

Macrae, FL orcid.org/0000-0002-7092-0422, Duval, C orcid.org/0000-0002-4870-6542, Papareddy, P et al. (13 more authors) (2018) A fibrin biofilm covers blood clots and protects from microbial invasion. Journal of Clinical Investigation, 128 (8). pp. 3356-3368. ISSN 0021-9738

Hethershaw, EL orcid.org/0000-0002-4366-278X, Adamson, PJ, Smith, KA orcid.org/0000-0001-5695-7117 et al. (7 more authors) (2018) The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit. Journal of Thrombosis and Haemostasis, 16 (7). pp. 1391-1401. ISSN 1538-7933

Mangin, PH, Onselaer, MB, Receveur, N et al. (16 more authors) (2018) Immobilized fibrinogen activates human platelets through glycoprotein VI. Haematologica, 103 (5). pp. 898-907. ISSN 0390-6078

Ichinose, A, Kohler, HP and Philippou, H (2017) Recommendation for ISTH/SSC Criterion 2015 for autoimmune acquired factor XIII/13 deficiency. Thrombosis and Haemostasis, 116 (04). pp. 772-774. ISSN 0340-6245

Bridge, KI, Bollen, L, Zhong, J et al. (7 more authors) (2017) Thrombin-Activatable Fibrinolysis Inhibitor in Human Abdominal Aortic Aneurysm Disease. Journal of Thrombosis and Haemostasis, 15 (11). pp. 2218-2225. ISSN 1538-7933

Onselaer, M-B, Hardy, AT, Wilson, C et al. (11 more authors) (2017) Fibrin and D-dimer bind to monomeric GPVI. Blood Advances, 1 (19). pp. 1495-1504. ISSN 2473-9529

Byrnes, JR, Wilson, C, Boutelle, AM et al. (4 more authors) (2016) The interaction between fibrinogen and zymogen FXIII-A₂B₂ is mediated by fibrinogen residues γ390-396 and the FXIII-B subunits. Blood, 128 (15). pp. 1969-1978. ISSN 0006-4971

Thomas, A, Biswas, A, Dodt, J et al. (5 more authors) (2016) Coagulation Factor XIIIA Subunit Missense Mutations Affect Structure and Function at the Various Steps of Factor XIII Action. Human Mutation, 37 (10). pp. 1030-1041. ISSN 1059-7794

Lau, YC, Hardy, LJ, Philippou, H et al. (2 more authors) (2016) Altered fibrin clot structure in patients with atrial fibrillation and worsening renal function. Thrombosis and Haemostasis, 116 (3). pp. 408-409. ISSN 0340-6245

Gupta, S, Biswas, A, Akhter, MS et al. (7 more authors) (2016) Revisiting the mechanism of coagulation factor XIII activation and regulation from a structure/functional perspective. Scientific Reports, 6. 30105. ISSN 2045-2322

Mouapi, KN, Bell, JD, Smith, KA et al. (3 more authors) (2016) Ranking reactive glutamines in the fibrinogen αC region that are targeted by blood coagulant factor XIII. Blood, 127 (18). pp. 2241-2248. ISSN 0006-4971

Duval, C orcid.org/0000-0002-4870-6542, Ali, M, Chaudhry, WW et al. (3 more authors) (2016) Factor XIII A-Subunit V34L Variant Affects Thrombus Cross-Linking in a Murine Model of Thrombosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 36 (2). pp. 308-316. ISSN 1079-5642

Domingues, MM, Macrae, FL orcid.org/0000-0002-7092-0422, Duval, C orcid.org/0000-0002-4870-6542 et al. (7 more authors) (2016) Thrombin and fibrinogen γ' impact clot structure by marked effects on intrafibrillar structure and protofibril packing. Blood, 127 (4). pp. 487-495. ISSN 0006-4971

Konings, J, Hoving, LR, Ariens, RS orcid.org/0000-0002-6310-5745 et al. (7 more authors) (2015) The role of activated coagulation factor XII in overall clot stability and fibrinolysis. Thrombosis Research, 136 (2). pp. 474-480. ISSN 0049-3848

Duval, C, Allan, P, Connell, SDA et al. (3 more authors) (2014) Roles of fibrin α- and γ-chain specific cross-linking by FXIIIa in fibrin structure and function. Thrombosis and Haemostasis, 111 (5). 842 - 850. ISSN 0340-6245

Hethershaw, EL orcid.org/0000-0002-4366-278X, Cilia La Corte, AL, Duval, C orcid.org/0000-0002-4870-6542 et al. (4 more authors) (2014) The effect of blood coagulation factor XIII on fibrin clot structure and fibrinolysis. Journal of Thrombosis and Haemostasis, 12 (2). pp. 197-205. ISSN 1538-7933

Westbury, SK, Duval, C, Philippou, H et al. (8 more authors) (2013) Partial deletion of the αC-domain in the Fibrinogen Perth variant is associated with thrombosis, increased clot strength and delayed fibrinolysis. Thrombosis and Haemostasis, 110 (6). 1135 - 1144. ISSN 0340-6245

Smith, EL, Cardinali, B, Ping, L et al. (2 more authors) (2013) Elimination of coagulation factor XIII from fibrinogen preparations. Journal of Thrombosis and Haemostasis, 11 (5). pp. 993-995. ISSN 1538-7933

Book Section

Philippou, H, Duval, C and Ariëns, RA (2011) Factor XIII. In: Marder, VJ, Aird, WC, Bennett, JS and Schulman, S, (eds.) Hemostasis and Thrombosis: Basic Principles and Clinical Practice. Hemostasis and Thrombosis: Basic Principles and Clinical Practice . Lippincott Williams & Wilkins , 272 - 285. ISBN 9781608319060

Conference or Workshop Item

Cherrington, S, Hardy, L, Francis, RJ et al. (6 more authors) (2020) M1 Protein from Group A Streptococcus Regulates Fibrin Clot Formation, Structure and Fibrinolytic Potential. In: 28th Congress of the International Society on Thrombosis and Haemostasis, 12-14 Jul 2020, Milan, Italy (Online).

Proceedings Paper

Singh, S, Montazeri, N, Ivaskevicius, V et al. (7 more authors) (2018) M-­FPMED01-­005­ (298) | Prevalence ­of ­mild factor ­XIII ­deficiency­phenotype:­ Current ­update to ­the ­WFH ­sponsored ­CRGP ­study. In: Haemophilia. WFH 2018 World Conference, 20-24 May 2018, Glasgow, Scotland. Wiley , p. 40.

Mouapi, KN, Bell, J, Smith, K orcid.org/0000-0001-5695-7117 et al. (3 more authors) (2017) Fibrinogen alpha C (233-425): A model protein for characterizing cross-linking by the transglutaminase factor XIII. In: 253rd ACS National Meeting. 253rd ACS National Meeting, 02-06 Apr 2017, San Francisco, California. ACS publications .