Items where authors include "O'Brien, Peter"

Article

Seling, Nico, Atobe, Masakazu, Kasten, Kevin et al. (4 more authors) (2023) α-Functionalisation of Cyclic Sulfides Enabled by Lithiation Trapping. Angewandte Chemie International Edition. e202314423. ISSN 1433-7851

FitzGerald, Edward A., Vagrys, Darius, Opassi, Giulia et al. (13 more authors) (2023) Multiplexed experimental strategies for fragment library screening against challenging drug targets using SPR biosensors. SLAS Discovery. ISSN 2472-5552

Jones, S. Paul, Firth, James D., Wheldon, Mary C. et al. (11 more authors) (2022) Exploration of piperidine 3D fragment chemical space : synthesis and 3D shape analysis of fragments derived from 20 regio- and diastereoisomers of methyl substituted pipecolinates. RSC Medicinal Chemistry. pp. 1614-1620. ISSN 2632-8682

Klein, Hanna F., Hamilton, David J., de Esch, Iwan J.P. et al. (2 more authors) (2022) Escape from planarity in fragment-based drug discovery : A synthetic strategy analysis of synthetic 3D fragment libraries. Drug discovery today. pp. 2484-2496. ISSN 1359-6446

Hamilton, David J., Beemsterboer, Marieke, Carter, Caroline M. et al. (6 more authors) (2022) Puckering the Planar Landscape of Fragments : Design and Synthesis of a 3D Cyclobutane Fragment Library. ChemMedChem. e202200113. ISSN 1860-7187

Gomez-Angel, Andres R., Donald, James R. orcid.org/0000-0002-2176-4902, Firth, James D. et al. (4 more authors) (2021) Synthesis and functionalisation of a bifunctional normorphan 3D building block for medicinal chemistry. Tetrahedron. 131961. ISSN 0040-4020

Kwong, Alice, Firth, James D., Farmer, Thomas J. orcid.org/0000-0002-1039-7684 et al. (1 more author) (2021) Rapid “high” temperature batch and flow lithiation-trapping of N-Boc pyrrolidine. Tetrahedron. 131899. ISSN 0040-4020

Makraki, Eleni, Darby, John F. orcid.org/0000-0003-2754-6348, Carneiro, Marta G. et al. (6 more authors) (2020) Fragment-derived modulators of an industrial β-glucosidase. The Biochemical journal. pp. 4383-4395. ISSN 1470-8728

O'Brien, Peter orcid.org/0000-0002-9966-1962, Downes, Thomas D, Jones, S Paul et al. (15 more authors) (2020) Design and Synthesis of 56 Shape Diverse 3-D Fragments. Chemistry : A European Journal. ISSN 1521-3765

Ho, Hon Eong orcid.org/0000-0003-1037-2505, Pagano, Angela, Rossi-Ashton, James A. et al. (7 more authors) (2020) Visible-light-induced intramolecular charge transfer in the radical spirocyclisation of indole-tethered ynones. Chemical Science. pp. 1353-1360. ISSN 2041-6539

Ho, Hon Eong orcid.org/0000-0003-1037-2505, James, Michael J orcid.org/0000-0003-2591-0046, O'Brien, Peter orcid.org/0000-0002-9966-1962 et al. (2 more authors) (2018) Ag(I)-Catalyzed Synthesis of Azabicyclic Alkaloid Frameworks from Ketimine-Tethered Ynones : Total Synthesis of Indolizidine 209D. Organic Letters. pp. 1439-1443. ISSN 1523-7052

Firth, James D, Canipa, Steven J, O'Brien, Peter orcid.org/0000-0002-9966-1962 et al. (1 more author) (2018) Gram-Scale Synthesis of the (-)-Sparteine Surrogate and (-)-Sparteine. Angewandte Chemie International Edition. pp. 223-226. ISSN 1433-7851

Firth, James D, O'Brien, Peter orcid.org/0000-0002-9966-1962 and Ferris, Leigh (2017) General Procedures for the Lithiation/Trapping of N-Boc Piperazines. The Journal of organic chemistry. pp. 7023-7031. ISSN 1520-6904

Clarke, Aimee K, James, Michael J orcid.org/0000-0003-2591-0046, O'Brien, Peter orcid.org/0000-0002-9966-1962 et al. (2 more authors) (2016) Silica-Supported Silver Nitrate as a Highly Active Dearomatizing Spirocyclization Catalyst : Synergistic Alkyne Activation by Silver Nanoparticles and Silica. Angewandte Chemie International Edition. pp. 13798-13802. ISSN 1433-7851

James, Michael J. orcid.org/0000-0003-2591-0046, O'Brien, Peter orcid.org/0000-0002-9966-1962, Taylor, Richard J K orcid.org/0000-0002-5880-2490 et al. (1 more author) (2016) Selective Synthesis of Six Products from a Single Indolyl α-Diazocarbonyl Precursor. Angewandte Chemie International Edition. pp. 9671-9675. ISSN 1433-7851

Liddon, John T R orcid.org/0000-0002-5287-9817, James, Michael J. orcid.org/0000-0003-2591-0046, Clarke, Aimee K. et al. (3 more authors) (2016) Catalyst-driven scaffold diversity : selective synthesis of spirocycles, carbazoles and quinolines from indolyl ynones. Chemistry : A European Journal. 8777–8780. ISSN 1521-3765

Chambers, Sarah J, Coulthard, Graeme, Unsworth, William Paul orcid.org/0000-0002-9169-5156 et al. (2 more authors) (2016) From Heteroaromatic acids and Imines to Azaspirocycles : Stereoselective Synthesis and 3D Shape Analysis. Chemistry : A European Journal (Weinheim an der Bergstrasse, Germany). pp. 6496-6500. ISSN 1521-3765